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Zithrocin (Azithromycin)
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Zithrocin

Zithrocin belongs to a group of Macrolide Antibiotics useful for treating numerous infections caused by bacteria like middle ear infections, traveler's diarrhea. Along with other medications, it is sometimes used for malaria. It is also used to treat a number of intestinal infections and sexually transmitted infections including gonorrhea and chlamydia. Administration of the medicine takes place either by mouth or intravenously with doses once per day.

Other names for this medication:
Altezym, Amovin, Azalid, Azatril, Azibiot, Azirox, Azithrox, Azitrin, Azitro, Binozyt, Disithrom, Gramokil, Hemomycin, Kromicin, Magnabiotic, Misultina, Nifostin, Pretir, Rozith, Tanezox, Zaret, Zedd, Zemycin, Zibac, Zithrocin, Zithromycin, Zithrox, Zitroneo

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Also known as: Azithromycin

Description

Zithrocin (Zithrocin tablets and Zithrocin for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Zithrocin has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Zithrocin is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Zithrocin, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Zithrocin is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Zithrocin for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Use Zithrocin as directed by your doctor.

Take Zithrocin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

Do not take an antacid that has aluminum or magnesium in it within 1 hour before or 2 hours after you take Zithrocin.

Zithrocin works best if it is taken at the same time each day.

To clear up your infection completely, use Zithrocin for the full course of treatment. Keep using it even if you feel better in a few days.

Ask your health care provider any questions you may have about how to use Zithrocin.

Overdose

If you take an overdose of Zithrocin you should visit your doctor or health care provider immediately. Symptoms of Zithrocin overdosage include discomfort in the stomach, diarrhea, retching and nausea.

Storage

Store Zithrocin below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zithrocin out of the reach of children and away from pets.

Side effects

The most common side effects associated with Zithrocin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use this medication if you have ever had jaundice or liver problems caused by taking azithromycin. You should not use azithromycin if you are allergic to it or to similar drugs such as erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), clarithromycin (Biaxin), telithromycin (Ketek), or troleandomycin (Tao).

There are many other medicines that can interact with azithromycin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Take this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Azithromycin will not treat a viral infection such as the common cold or flu.

Avoid taking an antacid within 2 hours before or after you take azithromycin. Some antacids can make it harder for your body to absorb azithromycin.

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This study measures trauma experiences of Rwandan women and identifies predictors associated with posttraumatic stress disorder (PTSD) and depressive symptoms. Nevertheless, few attempts have been made to estimate the properties of such mutations, and those studies that have been performed have been extremely labor intensive, relying on long-term, laboratory mutation-accumulation experiments. A vast literature has evolved regarding the epidemiology of most of the common cancers in women. Opticokinetic postnystagmus: a proposed new method of semeiological research in otoneurological practice (preliminary note). Concerning the relationship between dystrophia myotonica and peroneal muscular atrophy. We also use replica-exchange molecular dynamics simulations to elucidate the energetic landscape dictating the formation of stacked PTCDI structures. Simultaneous extraction of Cr(III) and Cr(VI) with a dithiocarbamate reagent followed by HPLC separation for chromium speciation. The compliance to the management of diabetes was better in patients with good knowledge. The incorporation of 32Pi into the 47 and 20 kDa polypeptides in platelets activated by wheat germ agglutinin (WGA) was studied. Knock-out of AIP1 in cells increases and overexpression of AIP1 reduces cellular PIP(2) levels.

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The role in plants of posttranslational modification of proteins with O-linked N-acetylglucosamine and the evolution and function of O-GlcNAc transferases responsible for this modification are reviewed. Carbon-14 biolabelling of wine polyphenols in Vitis vinifera cell suspension cultures. Satiation quantities of starches produced immediate and large decreases in the frequency of ruminating compared to ruminating under standard meal sizes. Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators. As NMR failed to define sufficiently rough constraints to ensure a convergence of a refinement process for such short and flexible peptides, the conformational space was first searched using the MCMM method.

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This modified procedure is useful for responding to subsequent additional ischemia in the area of the anterior cerebral artery and should be considered one of the optimal procedures for treating moyamoya disease. Uronic acid and uronic acid-hydroxyproline ratio in human aorta, myocardium, and skin. The level of virus-specific T-cell and macrophage recruitment in porcine reproductive and respiratory syndrome virus infection in pigs is independent of virus load. The authors review the recent continuous ambulatory peritoneal dialysis (CAPD) mortality literature and suggest that mortality can be improved by increasing the quantity of peritoneal dialysis delivered. ECM-mimicking nanostructured biomaterials have been shown to actively regulate cellular responses including attachment, proliferation, differentiation and matrix deposition. Based on these results, it is suggested that this sand fly is the most likely vector in the study area, suggesting the existence of a previously unknown sand fly-parasite association. The effects of silymarin on bronchoconstriction induced by antigen challenge and on post-antigen challenge hyperresponsiveness to substance P were evaluated in sensitized guinea-pigs. Carotid artery disease: natural history, diagnosis, and therapy. Complications with impaction, soiling, megarectosigmoid, and adverse responses to rectal enemas are inevitable and associated with long-term psychosocial dysfunction. Short tears (less than 2.5 centimeters) were associated with greater strength and range of motion than were long tears.

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Gene expression profiles are likely characteristic of subtypes of sarcomas and may be useful in diagnosis and classification of this heterogeneous group of tumors. Comparison of ultrasonographic transurethral and laparoscopic guided oocytes retrieval. The results support the role of p53 as an independent predictor of local failure in patients with squamous cell carcinoma of the head and neck who are treated by radical radiotherapy, suggesting that it may predict radioresistance. After 3 months, a greater mean reduction in synovial lining volume had occurred in response to intra-articular steroid alone compared to combined Sm-153 PHYP/steroid injection. Growth was determined by estimating the numbers of colony-forming units and colony diameter, as well as bacterial cell mass. Since functional nuclear complexes of beta-catenin with transcription factors have been identified recently, the knowledge of level and distribution of beta-catenin in sporadic colorectal tumors will give important insights into the intracellular mechanism of sporadic colorectal tumor initiation and progression. The significant changes of the cerebellum were complete or partial destruction of the cortex, deficiency of granules and/or Purkinje cells, clumping of the remaining granule cells, and an irregular cavity formation in the terminal portion of the folium. Performing more studies with larger sample sizes is necessary to confirm these results. Clinical features of Chlamydia pneumoniae acute respiratory infection. Mutational analysis of all cell lines revealed wild-type EGFR, KRAS, BRAF, and PI3K.

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The results demonstrate that this simple and efficient method can determine biotin concentration in the range of 10 pg to 50 ng/ml. Despite the lack of consensus of the role of spasticity in the observed motor disability in cerebral palsy (CP), alleviation of spasticity remains a primary focus in the clinical management of these patients. Alcohol and drug use, abuse, and dependence among welfare recipients. We provide evidence for the presence of an algD-independent promoter in this region which transcribes at least algL and algA, and which is regulated in a manner that differs from that of the algD promoter. Factors associated with physician interventions to address adolescent smoking. Determination of the stenotic aortic valve area in adults using Doppler echocardiography. The greatest improvement in the higher risk children were associated with fitness and home nutrition programmes. Smoothelin is a specific marker for smooth muscle neoplasms of the gastrointestinal tract. ELPs, for the first time, were successfully used as carriers for CTL vaccines. Blood shear stress in the laminar flow region was inversely correlated with the rate of thrombus formation and cell proliferation, and the percentage of smooth muscle a actin-positive cells.

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The reaction rate could be reduced but only slightly by increasing the ratio of PC to retinol. During the third stage (in males older than 175, and in females older than 60-70 days) the m. It was treated successfully by eliminating the Chap Stick and petroleum jelly, respectively, as well as by microincision and expression of the comedones. We investigated the expression of SDF-1alpha and its corresponding receptor, CXCR4, in human endometrial carcinoma (EMCA) tissues and the function of SDF-1alpha on EMCA cells with its regulation by CD26/DPPIV. Computer-controlled ventilation at Waterschei in the Kempen coal mines.

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This suggests that other polymerases can substitute for certain functions of polymerase epsilon. It was also assumed that patients diagnosed with AF received anticoagulant therapy, that some AF patients developed ischaemic stroke, and that some on anticoagulant therapy developed intracranial or gastrointestinal haemorrhage. The Eurodiab study: what has this taught us about diabetic peripheral neuropathy?. Unlike the poorly controlled patients, UBM parameters in group 1 were comparable to those in the controls. We found that naloxone-precipitated withdrawal of morphine-dependent rats increased c-Fos immunoreactivity (IR) in CRH positive neurons in the paraventricular hypothalamus.

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Protein tyrosine phosphatases (PTPs) are involved in the regulation of many aspects of cellular activity including proliferation, differentiation, metabolism, migration, and survival. A catheter attached to an osmotic minipump is inserted into the right superior vesical artery and advanced to the junction of the right common iliac artery. In addition, clioquinol concentrations in liver, kidney and brain of S-rats at 9 h after the administration were more than twice those of the R-rats. Nicotinamide methyltransferase (EC 2.1.1.1) has been purified over 1300-fold from porcine liver. The European Economic Community (EEC) is promoting a network of locally funded centers in the nine EEC countries, surveying a total of approximately 140,800 births per year for selected congenital malformations and multiple births. The study demonstrated that a 1-yr TCC program for low-risk patients with CABS could favorably enhance cardiorespiratory function. Interestingly, inactivation of ANF produced only a single major degradation product, which was isolated and purified. Reduced conversion of dehydroepiandrosterone into estrogens in women having hypogonadotropic hypogonadism associated with weight loss.

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Effects of the lipidosterolic extract of Serenoa repens (Permixon) on human prostatic cell lines. Following aspiration of PFCL, Fluid Air Exchange was done in all the cases and surgery completed uneventfully. Further, the influence on young people of peers and parents was also apparent. Hypothetical versus real preferences: results from an opportunistic field experiment. The paper is related to an analysis of the diurnal rhythm of mood in 87 adolescents suffering from circular schizophrenia. There also appeared to be an association between a familial haplotype and the immunologic defects. The experience has shown porous polyethylene reconstruction to be very efficient, with low morbidity and good cosmetic outcomes. MAC-IR appeared as numerous dots in clusters which co-localized with anti-NeuN labelled neurons in the injury border zone. Twelve adults who were first-degree relatives of patients with schizophrenia were evaluated for the presence of negative symptoms and neuropsychological deficits (in attention and working memory, long-term verbal memory and executive functions). We found that nardilysin (N-arginine dibasic convertase, also known as Nrd1 and NRDc), a metalloendopeptidase enhancer of protein ectodomain shedding, is a critical regulator of these processes.

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However, no significant difference was observed for IL-2 or interferon-gamma (IFN-gamma) production. Isosorbide dinitrate, a donor of nitric acid, lowers mean maternal BP and reduces the Doppler impedance in the umbilical and uterine arteries. A functional range of motion in the elbow and shoulder was regained in all but six patients, and they had severe skeletal or soft-tissue injuries in the same extremity. Taking into account the latest data described in the specialized literature, the authors present a clinical case of secondary traumatic glaucoma which was determined by a cystical shaped epithelial invasion of the anterior chamber. Vitamin E requirements of adult Standardbred horses evaluated by tissue depletion and repletion. We retrospectively reviewed 22 consecutive patients with A-pattern strabismus and mild-to-moderate superior oblique overaction on whom posterior tenectomy of the superior oblique at the scleral insertion was performed between January 1988 and August 1994. Gender differences in HIV-related self-reported knowledge, attitudes, and behaviors among college students. A research to develop a predicting system of mammalian subacute toxicity.

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Idiopathic twin aneurysm of right pulmonary artery diagnosed in a case 17 years after a successful surgical repair of ventricular septal defect. A simple surface electromyography (EMG) activation detection algorithm was developed for improved numerical definition of initiation and deactivation of muscle activity during periodic motion when maximum voluntary contractions are impractical to obtain. Clinical empiricism has recognized resistant breast cancer as a privileged target for docetaxel (Taxotere). Further studies are needed to evaluate the prognostic utility of PET/CT in the follow-up of head and neck cancer. when all the changes impact on individuals, either providers of care, or the patients themselves, then the issues are of concern on the personal level. PDGF-BB can promote the proliferation of tendon cells in a definite range of concentration and time. Previously, we developed a program (titled Bonfire) to facilitate digitization of neurite morphology and subsequent Sholl analysis and to assess changes to root, intermediate, and terminal neurites. The latter results belong with a program of interdisciplinary research applications of the new microprobe, which include studies of e.g., the monolayer lateral distribution of intercalant in SbCl5 intercalated graphite and of silicate minerals and iron distribution in sections of chondrules and their rims (components of chondrites, a class of stony meteorites). Offspring of rat dams that engage in high frequencies of high-arched-back nursing and pup-licking (High-LG) show attenuated stress responses compared to those engaging in lower frequencies (Low-LG). Intracavernous internal carotid artery (ICA) aneurysms can extend into the sella and simulate pituitary adenomas.

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The aim of this study was to investigate ERK activation (phosphorylation) in spinal dorsal horn neurons after acute uterine cervical distension. To optimize cofactor and substrate transit to UGT without compromising P450 activity, the pore-forming peptide alamethicin was used for microsomal perforation. Despite infrequent respiratory symptoms, histopathologic changes were identified in the lungs of 15 of 16 children dying of Rocky Mountain spotted fever (RMSF). Significant differences also emerged for DBP, BMI and AFA between the mean values of children positive for one parent and those negative for both parents and for BMI and AFA between the means of children positive for one parent and those positive for both parents. This result is interpreted as a stimulation of emission coupled to specific eigenmodes of a directional band gap. Does extraocular proprioception influence the development of visual processes and the oculomotor system?. ODC activity was initially high in the developing heart (150 pmol X mg protein-1 X 30 min-1) and decreased with age. Future study is required to confirm these results in larger, independent populations. Identifying distinct profiles of autism spectrum disorder in tuberous sclerosis complex can help optimize treatment across the life span.

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Polymorphism in one phocid species, the southern elephant seal (Mirounga leonina), was comparable to that seen in human populations, while the other phocid, the northern elephant seal (Mirounga angustirostris), has been through a severe population bottleneck and exhibited much less variation at this locus. Bacterial products released within the gut lumen may alter the course of inflammatory bowel lesions. In order to investigate the development of movement speed in relation to movement organization, children of 5, 6, 7, 8 and 9 years of age and adults carried out a reciprocal tapping task, in which time pressure biaxin drugs and distance were manipulated. Therefore it appears to be a mixture of aragonite and calcite whereas Biocoral is pure aragonite. Although wandering spleen is a rare clinical entity, the possibility of torsion should be kept in mind in the differential diagnosis of acute abdomen. The contribution of pneumolysin to the pathogenicity of Streptococcus pneumoniae. Do handball throws always exhibit a proximal-to-distal segmental sequence?. Barriers to treatment adherence included drug side effects, a perceived lack of provider support, patient financial constraints, conflicts with the timing of treatment services, alcoholism and social stigma.

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Present situation of medical care for foreigners at medical facilities in Chiba City. TEOAEs become compressively nonlinear as the MR increases, and this property is commonly exploited by obtaining a derived nonlinear response (DNLR) which reduces the MR artifact. Failure to excise the mesorectum completely has the potential to leave gross or microscopic residual disease that may in theory predispose to local failure. The model and the formula constitute a first attempt to ascertain the net present benefit of team supervision. Some morphological changes both in the heart itself and neurohormonal systems regulating it are dealt with. Goadsporin, a chemical substance which promotes secondary metabolism and Morphogenesis in streptomycetes. Immune thrombocytopenia after alpha-interferon therapy in patients with cancer. In nematodes in which protein carbonyls increased with age, one of the carbonylated proteins was identified as vitellogenin, an egg-yolk protein.

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Cyanoacetamide MCR (III): three-component Gewald reactions revisited. Total costs included direct medical costs for vaccination, physician visits, and treatment as well as indirect costs. Granulocyte colony-stimulating factor (G-CSF) and interleukin (IL)-8 in sera from patients with Staphylococcus aureus septicemia. Erythroderma associated with mixed lymphocyte-endothelial cell interaction and cleocin 150 mg 4 times a day Staphylococcus aureus infection. Induction of activator protein (AP)-1 and nuclear factor-kappaB by CD28 stimulation involves both phosphatidylinositol 3-kinase and acidic sphingomyelinase signals.

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Analysis of a multiphasic radiographic examination for detecting reflux esophagitis. We previously have characterized a pathogenic mtDNA mutation in the tRNAAsn gene. The non-glycosylated protein pre-placental lactogen was also cleaved to its mature form by tunicamycin membranes. To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours. Eighteen patients (8 sporadic cases and 10 siblings from 5 different families) between the age of 4 and 36 years with posterior microphthalmos. The caecal supernatants from germ-free, antibiotic-treated and control mice were compared with respect to their content of low-molecular-weight substances (less than 3500 mol. PHV occurred somewhat earlier in twin boys than in the controls. We believe that the unenhanced high-resolution fast spin-echo technique provides a cost-effective method for the diagnosis of acoustic schwannoma.

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Effect of gramicidin C on oxidative phorphorylation and respiration in rat liver mitochondria. The randomised controlled trial sets the gold standard of clinical research. No effects on radiosensitivity were seen in RT112 cells (expressing a functionally defective p53) at low caffeine doses (2 mM), but at higher doses (4 mM and 10 mM) caffeine caused both abrogation of radiation-induced G2 arrest and radiosensitization. The appearance of mRNA for the membrane form of mu precedes the appearance of mu secreted form mRNA. The hypothesis that the presence of cholelithogenic bile during the early stages of cholesterol gallstone formation promotes gallbladder absorption of water and electrolytes was tested in a prairie zithromax dosing kids dog gallstone model. E2F4 accumulated in the nucleus at the end of the S phase, remained nuclear during mitosis, and disappeared at the end of cytokinesis. A series of experiments performed with the two immuneprecipitation techniques, reducing or nonreducing electrophoretic conditions, and addition of preformed mock BA-1 immuneprecipitate to BA-1-Sepharose immuneprecipitates convincingly demonstrated that the previously described 55 and 65 kilodalton components were artifacts caused by co-migration of CD24 with IgG and IgM heavy chains, respectively. The barley BI-1 is a suppressor of nonspecific background resistance and mlo-mediated penetration resistance to the biotrophic fungal pathogen Blumeria graminis f. Alternatively, a light-sensitive diode connected to an oscilloscope can be used to determine the decay rate of the signal from an individual slit. These changes in vocal properties suggest that the vocalizations are important for mutual assessment of competitive abilities in females.

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accurate positioning and patency of the stent-grafts was ascertained by direct vision angioscopy in all cases. Our observations suggest that cardiac cells possess an innate capacity to re-establish complex, three-dimensional, cardiac organization in vitro. Recent evidence suggests that oxidation of low-density lipoprotein (LDL) may play an important role in the pathogenesis of atherosclerosis. Analysis on the epidemiology of syphilis in Guangdong province from 1995 - 1999 and the strategy for syphilis control. Even so, most myeloma patients will not be cured by high-dose therapy, but new strategies such as repeated autografting and post-graft alpha-interferon maintenance treatment seem to add additional advantages with respect to survival and freedom of disease progression. The analysis of author keywords helps in drawing the research trends in a special perspective. They probably constitute the entire chs multigenic family of this fungus, as revealed by careful analysis of six euascomycetes genomes.

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