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Zibac

Zibac is used to treat certain bacterial infections, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, sinuses, skin, throat, and reproductive organs.

Other names for this medication:
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Also known as: Azithromycin

Description

Zibac is in a group of drugs called macrolide antibiotics. Zibac fights bacteria in the body. Zibac is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Zibac may also be used for purposes other than those listed in this medication guide.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Zibac Tablets and other antibacterial drugs, Zibac Tablets should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Zibac Tablets are a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.

Zibac is an antibiotic used to treat bacterial infections of the nose, throat, lungs, bronchitis, ear, skin, soft tissues, and sexually transmitted genital and urinary infections.

Zibac is a semi-synthetic macrolide antibiotic of the azalide class. Like other macrolide antibiotics, Zibac inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Dosage

It is important that your child completes the course of antibiotic. This means that they must take the medicine for the number of days that the doctor has told you to, or until all the medicine has been taken. If you stop giving the antibiotic too soon, the troublesome bacteria that are left will start to multiply again, and may cause another infection. There is also a risk that these bacteria will be resistant to (no longer be killed by) the first antibiotic. This means that it might not work next time, and your child might need a different antibiotic, which might not work as well or cause more side-effects.

Children are sometimes sick (vomit) or get diarrhoea when taking antibiotics. Encourage them to drink water to replace the fluid they have lost. If it is severe or your child is drowsy, contact your doctor.

Do not give your child any medicine to stop the diarrhoea unless your doctor has told you to, as this can make things worse.

Try to give the medicine at about the same times each day, to help you remember, and to make sure that there is the right amount of medicine in your child’s body to kill the bacteria.

Only give this medicine to your child for their current infection.

Never save medicine for future illnesses. Give old or unused antibiotics to your pharmacist to dispose of.

Only give the antibiotic to the child for whom it was prescribed. Never give it to anyone else, even if their condition appears to be the same, as this could do harm.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Zibac overdose may include nausea, vomiting, diarrhea, and stomach discomfort.

Storage

Store Zibac below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zibac out of the reach of children and away from pets.

Side effects

The most common side effects associated with Zibac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure have been reported, some of which have resulted in death. Discontinue Zibac immediately if signs and symptoms of hepatitis occur.

The presence of other medical problems may affect the use of Zibac. Make sure you tell your doctor if you have any other medical problems, especially: allergy to any macrolide and ketolide antibiotic or liver disease with prior Zibac use or bacteremia (blood infection) or cystic fibrosis or infections, nosocomial or hospital-acquired or weak immune system or bradycardia (slow heartbeat) or hypokalemia (low potassium in the blood) or hypomagnesemia (low magnesium in the blood)

Not recommended in patients with these conditions: congestive heart failure or diarrhea or heart disease or Heart rhythm problems (e.g., prolonged QT interval), history of or Myasthenia gravis (severe muscle weakness).

Use with caution. May make these conditions worse: kidney disease, severe or liver disease. The effects may be increased because of slower removal of the medicine from the body.

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Following discharge with antihistamine therapy, he returned a month later with a visible enlargement of the right lateral neck and bilateral cervical adenopathy. It is concluded on the basis of data from the Framingham study and other large prospective studies that the rate of development of cardiovascular disease rises rapidly in relation to even modest amounts of adiposity. Here, we report a monoallelic expression pattern of the non-coding GC-elements flanking chromosomal internal var genes, and transcript from the active one was required for activation of the var gene in the same array. Providing PA advice and prescribing to reduce BP were perceived to be facilitated by similar diabetes-related behaviours (e.g., discussing cholesterol). This polyprotein system has many applications both as a research tool and for metabolic engineering and protein factory applications of plant biotechnology. The aim of the study was to conduct a systematic literature review to investigate the nature of cardiovascular disease health disparities among Afro-Caribbean origin populations and identify current knowledge gaps. Ten patients with total and one with partial anomalous pulmonary venous connection were studied by two-dimensional Doppler color flow-mapping echocardiography. The synergism deriving from EGFR and ErbB-2 blockade is mediated by several different alterations in the activation of signaling proteins and in the expression of cell cycle regulatory proteins, including transcriptional and posttranscriptional regulation of p27(kip1) expression. Systematic in vitro studies of osmotic shocks were performed by applying the ISM to agitated culture samples of H. HCN1 was almost exclusively expressed in SAN, emphasizing its utility as a new specific molecular marker of the human SAN and as a potential target of specific treatments intended to modify sinus rhythm.

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Changes in vascular permeability and dermal mucopolysaccharides in the female rat after parathyroidectomy. Isolation of cilia from porcine tracheal epithelium and extraction of dynein arms. Colocalisation of matrix metalloproteinase-9-mRNA and protein in human colorectal cancer stromal cells. Experiences with workflows for automating data-intensive bioinformatics. Ancient DNA reveals traces of Iberian Neolithic and Bronze Age lineages in modern Iberian horses. Personal exposure, behavior, and work site conditions as determinants of blood lead among bridge painters. Formation and degradation of urea derivatives in the azide method of peptide synthesis.

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We suggest that transient presynaptic changes within the dorsal striatum following disruption of the ventral striatum may mediate some general aspects of loss and recovery of behavior related to the time course of 6-hydroxydopamine neurotoxicity. Both in vitro and in vivo data showed that LUADT1 knockdown significantly inhibited proliferation of LUAD cells and induced cell cycle arrest at the G0-G1 phase. Cardiac arrest (CA) can produce complex changes in somatosensory evoked potentials (SSEPs). Meiotic pairing in the nematode Caenorhabditis elegans is facilitated by chromosomal sites known as pairing centers that are tethered to the nuclear envelope. Fusarium kernel rot disease starburst symptomatology was characterized fully for the first time. Treatment with tetracyclines is effective if begun in the early stages of infection. Thrombosis of the right internal jugular vein caused by a catheter in the subclavian vein.

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