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Vagizol

Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

Other names for this medication:
Aminidazole, Anazol, Aristogyl, Dequazol, Etron, Flagicure, Giardyl, Menilet, Metco, Metrolag, Metrolotion, Metronidazol, Metronidazols, Metroson, Metrozin, Mtronidazole, Nidazole, Orvagil, Robaz, Rosaced, Rosasol, Rozacrme, Rozagel, Trogyl, Vagimid, Vandazole

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Also known as: Metronidazole

Description

Vagizol (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Vagizol is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

Vagizol 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Vagizol and 250 on the other side; bottles of 50, 100, and 2,500. Vagizol 500-mg tablets are oblong, blue, film coated, with Vagizol debossed on one side and 500 on the other side; bottles of 50, 100, and 500.

Overdose

Single oral doses of Vagizol, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Vagizol has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Vagizol overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Vagizol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Metronidazole is mainly metabolised by hepatic oxidation. Substantial impairment of Metronidazole clearance may occur in the presence of advanced hepatic insufficiency. The risk/benefit ratio of using Metronidazole to treat trichomoniasis in such patients should be carefully considered. Plasma levels of Metronidazole should be closely monitored.

Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Liver function tests must be performed just prior to the start of therapy, throughout and after end of treatment until liver function is within normal ranges, or until the baseline values are reached. If the liver function tests become markedly elevated during treatment, the drug should be discontinued.

Patients with Cockayne syndrome should be advised to immediately report any symptoms of potential liver injury to their physician and stop taking metronidazole.

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This study was undertaken to identify Non Ulcer Dyspepsia (NUD) in young patients presenting with peptic ulcer like symptoms. The results suggest that the mutation of Abcg5 in SHRSPs, compared with Wistar rats, did not influence the ability for intestinal sitosterol absorption regardless of the dose. Longer CPB time, higher intraoperative blood loss, and reoperation are associated factors with the development of this disease. Gadolinium (Gd)-enhanced three-dimensional magnetic resonance angiography (MRA) is a more recent development that affords better spatial resolution. Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein noroxin 400 mg precio . A case of chlorpromazine poisoning during treatment of a patient with severe tetanus. Occlusion maneuver to detect the relative contribution of the rib cage and abdomen to tidal volume using respiratory inductive plethysmography in infants. Air toxic emissions from snowmobiles in Yellowstone National Park. Two such agents, interleukin-11 (IL-11) and thrombopoietin (TPO), have demonstrated promise in clinical trials. Therefore, by computed tomography this tumor cannot be differentiated from other primary or secondary adrenal tumors.

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Diagnostic and treatment of pulmonary embolism related acute pulmonary artery hypertension. There was a significant reduction of 65.0 and 70.5 per cent in rulide antibiotic dose malaria incidence in ZeroFly plastic sheeting area as compared to untreated plastic sheet and no sheet area respectively. Furthermore, there is some evidence to suggest that females may exploit the galleries of other females, at least under epidemic conditions. LSD (0.1 and 0.2 mg/kg) produced strong contralateral turning, indicating that it is a potent dopamine receptor agonist, while BOL (5 mg/kg), a non-hallucinogenic congener of LSD, was found to be a weak dopamine receptor agonist. The results reveal a diversity of ninhydrin-positive components present in the preparations, including free and peptide-bound amino acids, as well as other unidentified components, but not including any of the commonly occurring indoles, indoleamines or catecholeamines. In the experimental set-up, BALB/c mice were primed with intraperitoneal injections of recombinant Phl p 5a (rPhl p 5a) and subsequently aerosol challenged with the nebulized allergen. in the metabolism of iodinated compounds like erythrosine, a widely used colouring agent for certain foods. Such future research is a cornerstone for health promotion in the pursuit of reproductive health informed by omics systems sciences. The role of amino acid 106 and the sequence surrounding it for dimer-tetramer transition was confirmed by cloning the putative interface fragment of human TK1 and investigating its oligomerization pattern.

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