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Vagizol (Metronidazole)

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Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

Other names for this medication:
Aminidazole, Anazol, Aristogyl, Dequazol, Etron, Flagicure, Giardyl, Menilet, Metco, Metrolag, Metrolotion, Metronidazol, Metronidazols, Metroson, Metrozin, Mtronidazole, Nidazole, Orvagil, Robaz, Rosaced, Rosasol, Rozacrme, Rozagel, Trogyl, Vagimid, Vandazole

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Also known as: Metronidazole


Vagizol (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Vagizol is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Vagizol 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Vagizol and 250 on the other side; bottles of 50, 100, and 2,500. Vagizol 500-mg tablets are oblong, blue, film coated, with Vagizol debossed on one side and 500 on the other side; bottles of 50, 100, and 500.


Single oral doses of Vagizol, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Vagizol has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Vagizol overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Vagizol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Metronidazole is mainly metabolised by hepatic oxidation. Substantial impairment of Metronidazole clearance may occur in the presence of advanced hepatic insufficiency. The risk/benefit ratio of using Metronidazole to treat trichomoniasis in such patients should be carefully considered. Plasma levels of Metronidazole should be closely monitored.

Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Liver function tests must be performed just prior to the start of therapy, throughout and after end of treatment until liver function is within normal ranges, or until the baseline values are reached. If the liver function tests become markedly elevated during treatment, the drug should be discontinued.

Patients with Cockayne syndrome should be advised to immediately report any symptoms of potential liver injury to their physician and stop taking metronidazole.

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Nucleostemin- and Oct 3/4-positive stem/progenitor cells exhibit disparate anatomical and temporal expression during rat Achilles tendon healing. Autoregulation of mariner transposase activity by overproduction and dominant-negative complementation. Direct visual resolution of gene copy number in the human photopigment gene array. In both men and women, the ages for the onset and completion of puberty were also normal. The theory that attention-deficit/hyperactivity disorder (ADHD) stems from a deficit in an executive behavioral inhibition process has been little studied in adults, where the validity of ADHD is in debate.

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We report a case of 58 year old Caucasian male who presented with a 5 month history of increased frequency of urination, nocturia and weight loss without any fever or hematuria. Intriguingly, expression of the human cell-cycle inhibitor p21 or its Drosophila homolog dacapo (dap) can suppress both Dp53-induced cell death and differentiation defects in Drosophila eyes. A kinetic study of the reaction was performed by changing some parameters, such as reaction buffer pH, reaction buffer concentration and the initial concentration of BSA. Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands. Familiarity with the grief process allows the physician to intervene when necessary and to facilitate the normal sequence of grieving which, if thwarted, has serious ramifications. As the field of hair transplantation changes radically almost month to month, one goal remains essentially unchanged-satisfy the patient. We developed a Teflon plunge electrode system (Teflon plunge) with important advantages over currently used electrodes.

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The Social Context of Depression Symptomology in Sexual Minority Male Youth: Determinants of Depression in a Sample of Grindr Users. Descriptive, cross-sectional study, collecting medical histories in accordance with Mexican Official Standard NOM-004-SSA3-2012, and classifying respondents into age groups. Lineweaver-Burk plots for inhibition of plasmepsin II by LCu(CH(3)COO)(2) and LCuCl(2) show that the inhibition is competitive with respect to the substrate. infusion) is the most convenient and effective and has demonstrated an excellent safety profile with long-term use. Moreover, p-IgA and S-IgA enhance TNF-alpha release by HAM through an alternative pathway distinct from ERK1/2. Spontaneous and mitomycin C-induced sister chromatid exchanges (SCEs) in ceftin generic dosage lymphocytes were analyzed in 24 non-smokers and 24 sex- and age-matched smokers. The vitality of the tissues used was not impaired by the nanoparticles. Severe closed head injuries include epidural hematomas, acute subdural hematomas, intracerebral hematomas, intraventricular hematomas, subarachnoid hemorrhages, and diffuse axonal injuries. A newly developed human immunoglobulin preparation for intravenous use, SM-4300, had been studied in the field of surgery.

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This study was undertaken to identify Non Ulcer Dyspepsia (NUD) in young patients presenting with peptic ulcer like symptoms. The results suggest that the mutation of Abcg5 in SHRSPs, compared with Wistar rats, did not influence the ability for intestinal sitosterol absorption regardless of the dose. Longer CPB time, higher intraoperative blood loss, and reoperation are associated factors with the development of this disease. Gadolinium (Gd)-enhanced three-dimensional magnetic resonance angiography (MRA) is a more recent development that affords better spatial resolution. Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein noroxin 400 mg precio . A case of chlorpromazine poisoning during treatment of a patient with severe tetanus. Occlusion maneuver to detect the relative contribution of the rib cage and abdomen to tidal volume using respiratory inductive plethysmography in infants. Air toxic emissions from snowmobiles in Yellowstone National Park. Two such agents, interleukin-11 (IL-11) and thrombopoietin (TPO), have demonstrated promise in clinical trials. Therefore, by computed tomography this tumor cannot be differentiated from other primary or secondary adrenal tumors.

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