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Vagimid (Metronidazole)

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Vagimid eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Acuzole, Anabact, Anaeromet, Biozyl, Deflamon, Elyzol, Flagystatine, Flanizol, Flazol, Ginkan, Medazol, Menilet, Metco, Metrofusin, Metronex, Novazole, Orvagil, Perilox, Polibiotic, Robaz, Rosiced, Rovamet, Servizol, Trichazole, Trichex, Trichomonacid, Trichopol

Similar Products:
Noroxin, Chloromycetin, Zithromax, Duricef, Biaxin, Sumycin

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Also known as: Metronidazole


Vagimid (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Vagimid is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Vagimid 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Vagimid and 250 on the other side; bottles of 50, 100, and 2,500. Vagimid 500-mg tablets are oblong, blue, film coated, with Vagimid debossed on one side and 500 on the other side; bottles of 50, 100, and 500.


Single oral doses of Vagimid, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Vagimid has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Vagimid overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Vagimid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


As a rule, the usual duration of therapy with i.v Metronidazole or other imidazole derivatives is usually less than 10 days. This period may only be exceeded in individual cases after a very strict benefit-risk assessment. Only in the rarest possible case should the treatment be repeated. Limiting the duration of treatment is necessary because damage to human germ cells cannot be excluded.

Intensive or prolonged Metronidazole therapy should be conducted only under conditions of close surveillance for clinical and biological effects and under specialist direction. If prolonged therapy is required, the physician should bear in mind the possibility of peripheral neuropathy or leucopenia. Both effects are usually reversible.

In case of prolonged treatment, occurrence of undesirable effects such as paraesthesia, ataxia, dizziness and convulsive crises should be checked. High dose regimes have been associated with transient epileptiform seizures.

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Selective tyrosine kinase inhibitor imatinib (STI571) in haematological and oncological disease. Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1. Logistics as the tool of regulation and development of potential of health care system of the State Frontier Service of Ukraine. Exploration of the model allowed us to characterize various group properties, including spatial distribution, size, growth, rate of birth, lifespan, and persistence in the presence of synaptic turnover. F in a dose of 25 micrograms protected 2 of the 9 children, in a dose of 50 mg protected 4 of the 9 and in doses of 100 and 200 micrograms protected all children. Behavior of serum magnesium in infants in relation to various types of feeding. The largest number of eggs undergoing fertilization at both temperatures occurred after storage for 1 and 2 hours with the number decreasing over the remaining 6 hours. We take into account the influence of the ECM on cell motion and more particularly the alignment process along the fibers.

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The application of Immuno-gold and silver stainning to detecting OLP and DL. The resultant combined monitoring approach emphasizes the strengths of each technique and minimizes their weaknesses. cenocepacia infections in patients with cystic fibrosis referred to our pulmonary transplant centre and is associated with poor transplant outcomes using standard treatment regimens. Study of the electrokinetic properties of reconstituted sarcoplasmic reticulum vesicles. Tsc2 protein is expressed in the mammary ducts, salivary glands, gastric glands, parathyroid, small and large intestine, ovary and uterus. Two cases of reticulate acropigmentation of Dohi are reported, both patients demonstrating the typical features of this disorder. Good agreement with measured values is achieved only by using such assumptions. Traumatic and iatrogenic neurological complications after supracondylar humerous fractures in children. In order to find new potent source of bioactive molecules, we studied the cytotoxic activity of the essential oils from the flowers and leaves of Callistemon citrinus. However, phosphorylation of this site turns over rapidly and mediates 14-3-3 binding to Rictor and mTORC2, providing possibility for altered interactions of the complex.

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ATP-binding site of human brain hexokinase as studied by molecular modeling and site-directed mutagenesis. Most of the behaviors that were significantly correlated with age and body weight for the males were also correlated in the same direction with FSH and testosterone levels and testicular volume, but not with DHA or DHAS levels. High antigen valence is required to achieve stable binding to cells and subsequent activation, which is consistent with estimated Ti-FL association constants of less than 3 X 10(5) l/mol. A new skeleton method of identification of 13 peeled snake-drugs. lactis strain in microfiltration fermentation is 1,000-fold higher than obtained using the wild-type.

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Human platelet lipoxygenase activity toward several eicosaenoic acids was measured in intact cells as well as in subcellular fractions (cytosol and membranes). 16 patients eventually required surgery and only one patient defaulted on follow-up. Furthermore, a synthetic dimer of marmycin A and the lysosome-targeting agent artesunate exhibited a synergistic activity against the invasive MDA-MB-231 cancer cell line. However, identical substitutions occur at only 15 of these sites, and each protein also differs from the consensus at five (boar) or ten (rat) additional locations that are not shared. Administration of thiorphan alone at a dose of 25 micrograms/mouse or in combination with bestatin (50 micrograms) or captopril (5 mg/mouse) decreased the number of spontaneous metastases in lungs of Lewis lung carcinoma bearing mice. Significance of cardiotachography for diagnosis of existing conditions in the newborn infant. To describe the clinical, immunohistochemical and prognostic features, as well as outcomes of a large series of patients with orbital and periorbital diffuse large B-cell lymphoma (DLBCL). Mostly, reports have concentrated on applications relative to congenital deformities. The data come from a larger study focused on the empowerment of DCWs in NHs. There was an association between preterm birth and alcohol intake when consumption occurred 2 or more times per month.

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Levels in breast milk samples were 36.2-314 ng ml-1 and 0-333 ng ml-1 for meperidine and normeperidine, respectively. Echocardiographic pulmonic valvular motion in idiopathic hypertrophic subaortic stenosis. Thus, in the avian telencephalon, there is a separation of visual motion and spatial-pattern perception as there is in the mammalian telencephalon. N-(1-Deoxy-D-fructos-1-yl) fumonisin B(1) was synthesized by reacting fumonisin B(1) with an excess of D-glucose in methanol and heating for 6 h at 64 degrees C. Endoscopic implantation of a biopolymer in the lower esophageal sphincter for gastroesophageal reflux: a pilot study. A balloon angioplasty catheter was used to dilate the femoral vein puncture site before placement of a Greenfield vena caval filter in nine patients. A new technique of abdominal aortic aneurysmectomy in renal transplant patients is described. The results reveal that the laboratory studies usually reported in the literature to explain the fate of pesticides in amended soils are insufficient to explain azoxystrobin behaviour under real conditions.

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Perceived spatial organization of cutaneous patterns on surfaces of the human body in various positions. Previous literature has shown that compression plating is a reliable technique for achieving rigid fixation and fusion in adults. We have generated mice in which ephrinB2 is specifically deleted in the endothelium and endocardium of the developing vasculature and heart. Only a few of those sampled did not experience additional relapses--a pessimistic finding at 12-year follow-up. In acute myeloid leukemia (66 cases studied), the proteins were expressed in most cases in a high percentage of cells, especially BAX and CPP32, without correlation with hematological characteristics. Trial quality assessments and data extraction were undertaken by the reviewer. the results confirm that RA patients have raised levels of antibody to P. Since combination therapy has recently been shown to be superior to monotherapy, antiretrovirals will increasingly be given in combination.

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Absorption of sediment-bound radionuclides through the digestive tract of marine demersal fishes. Short chain fatty acid content decreased in the hippocampus while short chain fatty acid content increased in the striated skeletal muscles. Here, we report a rare association between the syndrome and an overt, major primary antibody deficiency disorder (common variable immune deficiency) which was successfully managed with immunoglobulin replacement therapy. These chronic infections are often asymptomatic but over time may cause biliary thickening, cholangitis, and a predisposition to cholangiocarcinoma. Invisible suffering: breathlessness in and beyond the clinic--a reply. In the neighboring hypothenar region, an unusual abductor digiti minimi was also observed. Indeed, patients often satisfy several sets of categorical criteria simultaneously.

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Assessing the impact of a modified informed consent process in a South African HIV/AIDS research trial. The key rate-limiting functional genes were pytH and pobA, and the relative contributions of these genes to the degradation process were examined with a path analysis. Three new 14beta-benzoyloxy taxoids containing an oxetane ring, namely, 14beta-benzoyloxybaccatin IV (1), 14beta-benzoyloxy-13-deacetylbaccatin IV (2), and 14beta-benzoyloxy-2-deacetylbaccatin VI (3), have been isolated from the leaves and stems of Taxus chinensis. Hierarchical semicrystalline block copolymer nanoparticles are produced in a segmented gas-liquid microfluidic reactor with top-down control of multiscale structural features, including nanoparticle morphologies, sizes, and internal crystallinities. Addition of inhaled salmeterol to inhaled corticosteroids in patients with poorly controlled nocturnal asthma. The MO, BK and especially CAP groups showed histological evidence of vasodilatation and polymorphonuclear leukocyte infiltration in the pulp tissue and a significant increase in plasma extravasation of Evans Blue dye, whereas mineral oil did not induce these changes. Vitamin B12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and up-regulates PP2A, proNGF, and TACE.

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Plasma acidification increases atrial natriuretic peptide as measured by radioimmunoassay. We have found a novel hMLH1 nonsense mutation in a Swiss family with Lynch syndrome, which has been transmitted through at least nine generations. Directly after the 24-h fast an oral glucose tolerance test (OGTT), with measurements of glucose, insulin and IGFBP-1 was performed. Mechanical cardiopulmonary support in children and young adults: extracorporeal membrane oxygenation, ventricular assist devices, and long-term support devices. An increased rate of thrombosis was also found with indwelling femoral vein catheter left in place for more than 24 hours, and infection. The intent of these measurements, along with measurements of the other ozone precursor, NO(x), was to provide an understanding of ozone zithromax breastfeeding category formation and the emissions loading and mix in the urban area. Such bursts occur regularly before onset of the corresponding surface paroxysms in a large proportion of the tested neurons.

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We performed an extraarticular resection of the hip joint including the spina iliaca anterior inferior, resection of the femur, and amputation of the lower leg. In vitro there was a similar loss of glucuronic acid conjugation of oxyclozanide by hepatic microsomes from infected cattle. Both may be considered a prognostic biomarker of CHD development. We examined tibial bone stress, accounting for geometry and applied loads, in runners with stress fracture. Here we studied the molecular mechanisms underlying the inhibitory activity of CD94/NKG2-A on NK cell functions by analyzing its interference on CD16-initiated signaling pathways involved in the control of cytolytic activity. Heat shock induces variably the major heat shock proteins of CV1 clones. The drug was concentrated, at shorter survival times, mainly in the blood stream and in highly vascularized organs.

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Immunoperoxidase studies using a panel of murine monoclonal antibodies demonstrate an antigenic phenotype specific for human renal cancer. Current understanding of photoinactivation is limited with competing hypotheses where the photosensitiser is either photosynthetic pigments or the Mn4CaO5 cluster itself, with little consensus on the mechanisms and consequences of PSII photoinactivation. Limitations and complications of the theory include changes in environment or genetic background, enzymes with sharply defined optima of activity, overdominance, pleiotropy, multifunctional enzymes and branched metabolic pathways. There is a significant association between the development of occupationally induced hand dermatitis and a history of atopy, particularly atopic dermatitis. The GLUT4 mRNA level in the cerebellum changed little in fasted or experimentally induced diabetic rats while those in adipose tissues decreased much. Antibody responses in the lower respiratory tract and male urogenital tract in humans after nasal and oral vaccination with cholera toxin B subunit. Like all professionals, nurses live with the inevitability of change. We report the first observation of subarachnoid hemorrhage in an infant with a urea cycle defect.

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This parasitic association had never been reported in our country or in Europe. Binding modes of a new epoxysuccinyl-peptide inhibitor of cysteine proteases. A patient with myasthenia gravis developed both Addison disease and primary hypothyroidism, with demonstrable anti-adrenal and antithyroid antibodies in her serum. Before the band is discharged, rotating the ligator through 180 degrees while applying suction will cause pain and give warning if the application site is not appropriate. Estrous cycles, decidual cell response and uterine estrogen and progesterone receptor in Fischer 344 virgin aging rats. The separation of the free and bound labeled hormone was performed by the dextran-coated charcoal method. Therapy of thalassemia major with transplant of the bone marrow. Some simple indices for evaluation of the nutritional state of chronic uremic patients treated with periodic hemodialysis.

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A preliminary experiment of cell-cell fusion between a human skin fibroblast cell line from a Lesch-Nyhan syndrome patient and an osteosarcoma cybrid cell line harboring the mitochondrial tRNALeu(UUR)A3243G mutation showed a decrease of A3243G mutant mtDNA in fused cells during passages. Modern studies report the causes of fatigue as either central or peripheral in origin. Mitochondria and mitochondria-tonofilament-desmosomal associations in the mammary gland secretory epithelium of lactating cows. Histologically, five cases were monophasic spindle cell lesions with a lacy appearance in areas with a prominent Alcian blue-positive myxoid stroma. Hence, these data further extend the analogy between the ubiquitin and SUMO pathway. The resulting cytoskeletons were fixed with glutaraldehyde and subjected to the indirect immunofluorescence procedure using monospecific tubulin antibodies. It is suggested that a correlation exists between changes in hippocampal serotonin metabolism and the retrievability of the passive avoidance response. Invasive Haemophilus influenzae disease and epiglottitis among Swiss children from 1980 to 1993: evidence for herd immunity among older age groups.

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Among them, synaptojanin, which associates with tyrosine kinase receptors through an adaptor protein, Ash/Grb2, in response to growth factors, is capable of hydrolyzing PtdIns(4,5)P2 bound to actin regulatory proteins, resulting in actin filament re-organization downstream of tyrosine kinases. A case of unexpected death associated with an aneurysm of the left ventricle caused by nonpenetrating chest trauma is described. Diagnostic value of Gram stain and culture of sputum and endotracheal aspirates in bacteremic pneumococcal pneumonia. cleocin 300 mg capsules Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. A comparison of sensitivities to chromatic and luminance stimuli has been carried out in patients with a past history of optic neuritis. Research is needed to determine the cause of unexplained stillbirth.

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Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation vantin 200 mg oral tablet . Renal COX-1 and COX-2 protein expression and distribution were analysed by Western blot and immunohistochemistry in nine rats with carbon tetrachloride-induced cirrhosis and ascites and 10 control animals. The proliferative state of clonogenic cells in the Lewis lung tumour after treatment with cytotoxic agents. A silicon analogue of vinyllithium: structural characterization of a disilenide. Red blood cells (RBCs) have an extensive antioxidant system designed to eliminate the formation of reactive oxygen species (ROS). It can be useful in anaesthesia and in intensive medicine for different purposes, e.g. Next, the BMP-4 plasmids were injected into mouse calf muscles, and transcutaneous electroporation was applied.

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The exigency of a critical incident can instantly transform resource rich environs, to those of austerity. The authors studied toxicological cases between 1989 and 1998 at the 1st Department of Medicine of the Medical and Health Science Centre, at the University of Debrecen, paying special attention to suicidal poisoning cases. The same populations were tested for their ability to bind to resident murine peritoneal macrophages (RPM) in vitro during a 20-min serum-free incubation period. Candidate biomarkers that are currently being investigated include protein surrogates of cell cycle deregulation (such as p16ink4a and minichromosomal maintenance proteins), DNA damage biomarkers (53BP1) in addition to testing for human papillomavirus genotype, gamma tubulin and beta defensin levels. Combined discrete subaortic stenosis, idiopathic hypertrophic subaortic stenosis and tetralogy of Fallot. Collectively, these results define biaxin liquid dosage the requirements of Arp5-Ies6 assembly, which are needed to couple ATP hydrolysis to productive nucleosome movement.

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Compounds 4, 5, and 7-9 were shown to be more active than verapamil in reversing vinblastine resistance in multidrug-resistant KB-V1 cells. Effects of dexamethasone on pulmonary and renal functions in patients undergoing CABG with cardiopulmonary bypass. In the present experiments we have further purified calf thymus extract by means of paper electrophoresis and chromatography on thin-layer cellulose plates. Placebo response rates in psychotic and nonpsychotic depression. The test method is discussed in relation to its applicability to the evaluation and comparison of bearing materials and surfaces, with particular application to total knee replacements. Because hypotension was the most prominent avian response to both CHE and ANP, endogenous vasoactive factor(s) in chicken hearts may function to regulate blood pressure rather than blood volume. The effect of lethal and superlethal doses of ionizing radiation (0.206, 0.309, and 9.288 C/kg) on ATPase activity of rat brain mitochondria has been investigated. Three case scenarios of asthma were given, and the doctors were asked to write a prescription for each case. It is recommended to carefully select a filter for a specific blood component and to perform leuco-depletion procedures under controlled conditions according ceftin antibiotic keflex to validated methods meeting Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP). Tests were made to determine the efficacy of uredofos in either the diet or drinking water for controlling induced Hymenolepis nana and naturally acquired Syphacia obvelata infections in the mouse.

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The most important conclusions of this consensus meeting are discussed in this short article. Comparison of HIV prevalences in community-based and antenatal clinic surveys in rural Mwanza, Tanzania. High-affinity potassium uptake system in Bacillus acidocaldarius showing immunological cross-reactivity with the Kdp system from Escherichia coli. Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model. ECM proteins typically include multiple, independently folded domains whose sequences and arrangement are highly conserved. We also demonstrated that the anti-sigma factor SpoIIAB can bind to sigma G in vitro. In patients cleocin brand with newly diagnosed medulloblastoma considered to have a good prognosis on the basis of low T stage, minimal residual tumor after at least subtotal resection, and no evidence of dissemination after thorough evaluation, there is an increased risk of early relapse associated with lowering the dose of neuraxis radiation from 3,600 cGy in 20 fractions to 2,340 cGy in 13 fractions. The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits. Patterned vertically aligned CNTBAs were synthesized using thermal chemical vapor deposition followed by the deposition of IrO(2) nanocrystals by reactive radio-frequency magnetron sputtering using an Ir target.

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