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Uniklar (Clarithromycin)

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Uniklar is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the ears, sinuses, skin, and throat. Uniklar is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)].

Other names for this medication:
Binoclar, Biotclarcin, Clarimax, Claripen, Claritt, Clariwin, Clarix, Clarogen, Claromac, Claron, Claxid, Cleron, Clonocid, Derizic, Egelif, Euromicina, Ezumycin, Hecobac, Helimox, Infex, Klabion, Klariger, Klarimac, Klarimax, Klarit, Klaritpharma, Klazidem, Klerimed, Klonacid, Kofron, Krobicin, Laricid, Larithro, Lekoklar, Maclar, Rodizim, Rolacin, Uniklar, Xylar, Zeclaren

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Also known as: Clarithromycin


Uniklar (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Uniklar works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Uniklar Filmtab and Uniklar Granules are recommended as the primary agents. Uniklar Filmtab and Uniklar Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Uniklar is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Uniklar therapy should continue if clinical response is observed. Uniklar can be discontinued when the patient is considered at low risk of disseminated infection.


Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Uniklar are:

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Snakes venom proteases from Agkistrodon rhodostoma, Bothrops marajoensis and Bothrops moojeni were further used for the analysis of H1 histones. This study evaluated interpretation of maximal CPET in a young adult cohort with known pulmonary disorders using published reference values compared to age-matched normal controls. In total, 16 enzymes, probably encoded by 18 loci, were studied for 3 populations of the diploid form sampled from 2 localities, and 4 populations of the triploid form from 4 localities. To characterize in vivo changes of adenylate cyclase activity in rabbit ciliary processes during the circadian cycle. Survival was estimated by the Kaplan-Meier method and compared by the log-rank test. The proliferation of SMCs was higher for scaffolds manufactured with glucose and, by day 28, scaffolds manufactured with glucose supported a higher cell population cleocin buy online uk than those processed using NaCl porogen. This study showed that thigh muscle composition, muscle strength, and body fat mass are important determinants of lower-body muscle power production during weight-bearing activity in healthy postmenopausal women. Patients with HIV are living longer now than in the past, and with a better quality of life. Case records of nine patients who developed a total of 14 episodes of TM were retrospectively studied.

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Acute disseminated encephalomyelitis: clinical features and HLA-DR linkage. One tumor existed for at least 15 years, the other for 3 years, both without metastasizing. One had congenital onset and predominant axial weakness, with poor neck control and inability to sit independently at the age of 21 months. Determination of the NH2-terminal sequence of both members of the doublet gave identical results: VTLNPSDPEHCQ. We encountered a case of an interhemispheric arachnoid cyst in a 54-year-old patient who had developed paraparesis. Taking into account their deleting effect on haemodynamic status and immune system, barbituric are levaquin loading dose no longer used as long term sedative agents. Diseases belonging to the circle of the Wiskott-Aldrich syndrome. A set of 13 monoclonal antibodies (MAbs) was generated against HPV-6 L1 virus-like particles (VLPs), screened for reactivity to HPV-6 and HPV-11 L1 VLPs by ELISA, and tested for neutralization of HPV-11 infection.

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Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones. Using plaque reduction neutralization test (PRNT), we examined the neutralizing activity of these mAbs. On multivariable analysis, we also assessed patient- and hospital-level characteristics that are associated with CR referral. Multiple interactions between the splicing substrate and small nuclear ribonucleoproteins in spliceosomes. There is a broad spectrum of lipomatous tumors that involve soft tissues including ordinary lipomas, variants of lipomas, heterotopic lipomas, lipomatosis, hibernomas and liposarcomas. To investigate the long-term efficacy of postoperative interferon-alpha (IFN-alpha) adjuvant therapy in preventing recurrence in non-metastatic renal cell carcinoma treated with radical nephrectomy and to identify related prognostic markers. Such acceleration of cell migration may have a significant impact on the development of treatments to enable faster, more cost-effective wound repair in many different types of tissues. These results suggest that the active metabolite MPC-Keto-H(2) contributes in part to the antihypertensive action of MPC, the delayed distribution of MPC into the effector site, or both.

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MRI of acute cerebral infarcts, increased contrast enhancement with continuous infusion of gadolinium. Patients with non-ST elevation acute coronary syndrome hospitalized in 38 hospitals in China were included in this registry study as part of an international multicentre registry-OASIS. pQDLDHVFLRFamide is a highly conserved crustacean neuropeptide with a structure that places it within the myosuppressin subfamily of the FMRFamide-like peptides. Compared amoxil liquid dosing with myofascial pain syndrome patients, fibromyalgia patients reported significantly more often fatigue, numbness, tingling, gastrointestinal discomfort, and poor sleep. Fifteen patients with post-circumcision squamous cell carcinoma of the penis are discussed (13 were referred from the southwestern region of Saudi Arabia).

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