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Tricofin (Metronidazole)

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Tricofin is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.

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Also known as: Metronidazole


Tricofin (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Tricofin is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


In elderly patients, the pharmacokinetics of metro- nidazole may be altered, and, therefore, monitor- ing of serum levels may be necessary to adjust the metronidazole dosage accordingly.


In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Tricofin overdose, Tricofin infusion should be discontinued. Patients should be treated symptomatically.


Store Tricofin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tricofin out of the reach of children and away from pets.

Side effects

The most common side effects associated with Tricofin are:

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Interaction with Alcohol. Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole.

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In 3,791 horses and ponies submitted to the Department of Internal Disease of Farm Animals of the Faculty of Veterinary Medicine, Utrecht, the faeces were studied for the presence of parasites. The preparation of R-phycoerythrin of the red alga Ceramium rubrum is described. A unique combination of inflammatory cytokines enhances apoptosis of thyroid follicular cells and transforms nondestructive to destructive thyroiditis in experimental autoimmune thyroiditis. A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos. We then performed a combinatorial analysis to identify which fragment combination best reconciled structural and taste distances. The effect of the calcium channel antagonist diltiazem was studied in five patients with severe pulmonary hypertension. Silencing of Foxc2 by RNAi in these cells led to EMT and increased cell migration. Coeliac disease is a treatable, gluten-induced disease that often occurs concurrently with other autoimmune diseases. This mast cell inhibitor is effective in the treatment of vernal keratoconjunctivitis, allergic conjunctivitis, chronic conjunctivitis, and giant papillary conjunctivitis, especially when a history of atopic disorders or moderately low blood IgE levels are present. Thus, we provide an example of a structural motif within the telomerase RNA that is required for telomerase function and identify the domain that is required for telomerase complex formation.

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