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Rotramin (Roxithromycin)

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Rotramin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Rotramin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Azuril, Bazuctril, Biostatik, Claramid, Delos, Infectoroxit, Ladlid, Macrolid, Makrodex, Odonticina, Overal, Redotrin, Rokithrid, Roksimin, Roksolit, Rolid, Romac, Romyk, Roxacine, Roxithromycin, Roxithromycinum, Roxitromicina

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Keflex, Ilosone, Myambutol, Duricef, Chloromycetin, Cipro, Cefixime, Floxin, Amoxil

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Also known as: Roxithromycin


Rotramin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Rotramin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Rotramin is available under several brandnames. Rotramin is not available in the United States. Rotramin is available in Australia, Israel and New Zealand. Rotramin has also been tested to possess antimalarial activity.

Rotramin prevents bacteria from growing, by interfering with their protein synthesis. Rotramin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Rotramin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.


Rotramin is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.


Symptomatic treatment should be provided as required. There is no specific antidote.


Keep the tablets in the foil until it is time to take them.

Keep the tablets/in a cool dry place where the temperature stays below 30 degrees C.

Do not store Rotramin or any other medicine in the bathroom or near a sink.

Do not leave it in the car on hot days or on window sills.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Rotramin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Rotramin if you are allergic to Generic Rotramin components. Try to be careful with Generic Rotramin if you're pregnant or you plan to have a baby, or you are a nursing mother. It can be dangerous to stop Generic Rotramin taking suddenly.

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