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Rolacin (Clarithromycin)

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Rolacin is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections,lyme disease,strep throat,skin infections, H. pyloriinfection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma,chlamydiaand mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Other names for this medication:
Abbotic, Bacterfin, Biclar, Biotclarcin, Clacine, Clarimycin, Claritab, Clarithromycin, Clarix, Clarocin, Claromac, Claromycin, Clarosip, Clatic, Claxid, Cleanomisin, Cleron, Clormicin, Euromicina, Fromilid, Geromycin, Italclar, Karid, Klabet, Klarimax, Klarit, Klarith, Klarithrin, Klazidem, Klerimed, Kleromicin, Klonacid, Larizin, Lekoklar, Macrol, Nutabact, Odycin, Quedox, Rocin, Rodizim

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Also known as: Clarithromycin


Rolacin (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Rolacin works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


Rolacin Filmtab and Rolacin Granules may be given with or without food.

Rolacin XL Filmtab should be taken with food. Swallow Rolacin XL Filmtab whole; do not chew, break or crush Rolacin XL Filmtab.

Triple therapy: Rolacin Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Rolacin Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Rolacin Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Rolacin Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Rolacin Filmtab/omeprazole. The recommended adult dosage is 500 mg Rolacin Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.


Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rolacin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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In some cases, one or two double labeled neurons were detected in the lateral hypothalamic area and nucleus raphe obscurus. Fifty-two dizzy patients with panic disorders and agoraphobia, 30 with panic disorders without agoraphobia, and 20 with depressive disorders underwent otoneurological screening with bithermal caloric stimulation. Ultrasonication or alkaline treatment released a marked amount of insoluble organic matter in a soluble form. Recurrent herpes genitalis, severe impairment of specific cell-mediated immune response and bilateral femoral head necrosis: report of a case. Differentiation of pluripotent stem cells on multiwalled carbon nanotubes. This data indicates that lesions of the LC produce decreased activity of dopaminergic brain neurons as well as supersensitivity of dopaminergic receptors. A case-control study was conducted to see whether a family history of CRC is associated with a higher prevalence of colorectal adenomas. Moderate doses of porcine somatotropin do not increase plasma insulin-like growth factor-I (IGF-I) or IGF binding protein-3. In the North, when winter meets spring, a surge of SAP, DAP and mean AP occurs as well as an increase in heart rate, number of patients with disturbed circadian profile of AP. Possible role of brain stem respiratory neurons in mediating vomiting during cleocin dose kids space motion sickness.

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Gene expression in PBMCs can be used as biomarkers to successfully predict disease outcomes among HIV-infected individuals treated with HAART. The phytochrome gene family cleocin 300 mg tid in grasses (Poaceae): a phylogeny and evidence that grasses have a subset of the loci found in dicot angiosperms. Exposures of 250 or 1000 ppm caused a number of deaths and hemangiosarcoma in the liver starting the ninth month. Origin of magnetic and magnetoelastic tweedlike precursor modulations in ferroic materials. Basic helix-loop-helix (bHLH) is one of the important transcription factors, which is essential for premature neural formation. Although no relationship between eosinophil-derived proteins in serum, NALF or urine and the level of nonspecific bronchial hyperreactivity could be detected, the concentrations of EPX in serum and urine were correlated with variables of pulmonary function. Tetanus remains a leading cause of maternal and neonatal morbidity and mortality in developing countries. Splenic flexure mobilization (SFM), anastomotic leakage, bleeding, and stricture rate were analyzed in this group.

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Reverse-phase high performance liquid chromatographic analysis revealed that alpha-rANP-LI with a low molecular weight in the spinal cord consisted of several components, two major components of which co-migrated with synthetic alpha-rANP (4-28) and alpha-rANP (5-28), whereas little immunoreactivity was eluted at the position of alpha-rANP. This procedure offers an economical alternative to commercial miniprep kits, utilizing silica resins or anion-exchanger matrices and, moreover, is more reliable and consistent with respect to reading lengths and accuracy in automated fluorescence sequencing. In layered preparations, treatment of the intact longitudinal strip with ouabain before layering prevented the relaxation, whereas pretreatment of the strip without endothelium had no effect.(ABSTRACT TRUNCATED AT 250 WORDS). Contact noroxin brand name dermatitis to topical acne drugs: a review of the literature. With early and more widespread use of biological and other innovative therapies, however, outcomes for patients with JIA should improve further. In comparison with both healthy subjects and patients receiving SSRIs, the TCA group displayed an increased movement time, reduced automation of handwriting, lower maximum velocities and reduced acceleration of descending strokes. Symptomatic epidural gas cyst associated with discal vacuum phenomenon.

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Gelonin, a single-chain protein which inactivates eukaryotic ribosomes, becomes split into peptides when incubated with SDS. Changes in N-acetyl-beta-D-glucosaminidase activity in the urine and urinary albumin excretion in magnesium deficient rats. Our purpose was to determine the efficacy of itraconazole for kerion and noninflammatory tinea capitis. To investigate whether antioxidants and copper chelators can modulate the uptake and the toxicity of copper ions in brain astrocytes, we used primary astrocytes as cell culture model. A basis for observer variation in electrocardiographic interpretation. Intervention The Optimising Management of Angina (OMA) programme includes a CDSS guiding investigation and medication decisions for clinicians managing patients with new onset stable angina, based on English national guidelines, introduced through an educational intervention. Isolation of actinomycetes from various soil samples of Ranchi district (Jharkhand) and studies on their antimicrobial activities. This small amount of IL2 was found to be crucial for the observed TRF activity.

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The adsorption of analytes onto the sample surfaces will sacrifice the detection sensitivity. Microvascular endothelial cell transwell membrane migration onto the fibronectin was also blocked by MAb L1A3. The iNOS-inducible phenotype was dominant in somatic cell hybrids generated by the fusion of nonmetastatic and metastatic cells, suggesting that no inhibitors of iNOS expression are norfloxacin 400 mg uses in tamil present in metastatic cells. Tissue-specific, inducible and functional expression of the E alpha d MHC class II gene in transgenic mice. Concerted efforts have recently been made by several laboratories to define the genetic basis of this disease in predisposed mice and humans. IFN-gamma and LPS differentially modulate class II MHC and B7-1 expression on murine renal tubular epithelial cells. The IgG1 antibody 31-9D induces anaemia by erythrocyte sequestration in the spleen and liver, whereas the IgG2a antibody 34-3C triggers erythrophagocytosis (Shibata et al., Int Immunol 1990. Known downstream flowering time genes CO and FT were elevated by DEX treatment, but not other proposed targets HAP3A and TOC1, indicating that the expression of these genes may be less directly regulated by GI. The thiobarbituric acid (TBA) colorimetric method was used to detect the lens malondialdehyde (MDA) content produced by LPO, and electron microscopy was used to observe the ultrastructure of rabbit lens epithelium. These results indicate that protein S-nitrosylation is regulated by the basic and acidic amino acids surrounding the target cysteine.

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Treatment of MCF-7 cells with the antifolate tomudex (TDX) and the DNA damaging agent oxaliplatin also caused up-regulation of each target gene. Eighteen turkeys naturally infected with Leucocytozoon smithi were separated into 3 groups of 6 each and were respectively exposed to conditions of natural, reversed, or continuous light. Estimated gradients are highly dependent on the definition of the vascular lumen, a process aided by the use of sonographic contrast. A possibility of selective evaluation of gastric secretive function. The MT neurons were simulated by first multiplying the outputs of conventional orientation selective V1 neurons and then normalizing the product. People examined in out-patient clinic as symptomatic cases, for health report or during contact examination, number of mycobacteriological and radiological examinations, and tuberculosis cases detected in each year. A delay of 12 hours is suggested between cerebral angiography and explanation, to decrease the combined harmful effects what class of medicine is flagyl of contrast media and ischemia on renal grafts.

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Our technique resulted in only small changes in statistical characteristics of individual subtraction SPET studies, and was acceptable for the purpose of creating composite SISCOM images. Stimulability considerations in the phonological treatment of a child with a persistent disorder of speech-sound production. NSAIDs down-regulate GATA-6 to transcriptionally up-regulate 15-LOX-1 and induce apoptosis in colorectal cancer cells. Clinical symptoms were not significant: bristled hair, conjunctivitis, sneezing and hypertrophy of mandibular and popliteal lymph nodes. Efficacy of oral tegafur-uracil (UFT) as adjuvant therapy as compared with classical cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in early breast cancer: a pooled analysis of two randomized controlled trials (N.SAS-BC 01 trial and CUBC trial). Stereotactic radiotherapy using a fractionated schedule provides a better tumor control rate and a similar rate of deterioration for hearing levels compared to an observation policy. The animals were given one week each of acclimation to the cages, saline, cocaine (19 mg/kg in 1 cc/kg saline), rest, two weeks on LiCl, and a week on LiCl plus the same dose of cocaine. Two gas chromatographic/mass spectrometric assays have been developed: one for the simultaneous quantification of OCB and 10-OH-CB, the other for CB-trans-diol. Corresponding to differences in susceptibility, the zone sizes differed for the two drugs with respect to certain bacterial groups, e.g. Identification of statistically and biologically relevant biomarkers from high-throughput data can be unreliable due to the nature of the data--e.g., high technical variability, small sample size, and high dimension size.

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Our observations strongly suggest that anoxia is a negative environmental signal for adhesion in E. A collaborative care management approach can help primary care providers assist older adults to address psychosocial concerns, cognitive functioning, and depression. Polygenic influences resulting in insulin resistance in the normal population are therefore likely to result in lower birthweight. Cysts were firm, tan, and filled with clear, yellow fluid, or were softer and filled with white, amorphous, marbled material and a smaller amount of clear, yellow fluid. Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers. Antimicrobial activity has been studied for more than 80 compounds. Aspirin reduced plasma concentrations of prostaglandin (PG) F alpha in 11 of 12 children with toddler diarrhoea, and usually, but not always, controlled the symptom. Audit in laboratory medicine may be defined as a process of review and assessment of laboratory performance, and its purpose should be to improve patient care by enhancing laboratory performance and making better use of resources. The morphologic assessment of lymph nodes in ultrasound allows for primary histologic and prognostic evaluation of lymph node metastases. A total of 2358 participants (1292 women, 1066 men) in the Framingham Heart Study who were free of hypertension, were not taking drugs affecting potassium homeostasis, and had serum potassium measured in 1979 to 1983 were followed for longitudinal tracking of BP and development of hypertension at examination 4 years later.

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Global environmental impacts of agricultural expansion: the need for sustainable and efficient practices. Regional differences in cerebral noradrenaline turnover in mice withdrawn from repeated morphine treatment and tolerance to the effects of acute morphine. We tested the expression of IGF-1R and calculated the survival in 61 SCLC patients. To determine the maximum tolerated doses (MTD) and the dose-limiting toxicities (DLTs) of the weekly administration of docetaxel and gemcitabine as first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). Change in the disease name for schizophrenia in Japan and its effect on informed consent given by physicians. Evidence will be provided that the protection of the genome integrity in terminally differentiated cells is achieved by different strategies than in proliferating cells. The relative roles of surgery and angioplasty should become better defined.

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