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Rolacin (Clarithromycin)
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Rolacin

Rolacin is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections,lyme disease,strep throat,skin infections, H. pyloriinfection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma,chlamydiaand mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Other names for this medication:
Abbotic, Bacterfin, Biclar, Biotclarcin, Clacine, Clarimycin, Claritab, Clarithromycin, Clarix, Clarocin, Claromac, Claromycin, Clarosip, Clatic, Claxid, Cleanomisin, Cleron, Clormicin, Euromicina, Fromilid, Geromycin, Italclar, Karid, Klabet, Klarimax, Klarit, Klarith, Klarithrin, Klazidem, Klerimed, Kleromicin, Klonacid, Larizin, Lekoklar, Macrol, Nutabact, Odycin, Quedox, Rocin, Rodizim

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Also known as: Clarithromycin

Description

Rolacin (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Rolacin works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

Rolacin Filmtab and Rolacin Granules may be given with or without food.

Rolacin XL Filmtab should be taken with food. Swallow Rolacin XL Filmtab whole; do not chew, break or crush Rolacin XL Filmtab.

Triple therapy: Rolacin Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Rolacin Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Rolacin Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Rolacin Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Rolacin Filmtab/omeprazole. The recommended adult dosage is 500 mg Rolacin Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rolacin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Gelonin, a single-chain protein which inactivates eukaryotic ribosomes, becomes split into peptides when incubated with SDS. Changes in N-acetyl-beta-D-glucosaminidase activity in the urine and urinary albumin excretion in magnesium deficient rats. Our purpose was to determine the efficacy of itraconazole for kerion and noninflammatory tinea capitis. To investigate whether antioxidants and copper chelators can modulate the uptake and the toxicity of copper ions in brain astrocytes, we used primary astrocytes as cell culture model. A basis for observer variation in electrocardiographic interpretation. Intervention The Optimising Management of Angina (OMA) programme includes a CDSS guiding investigation and medication decisions for clinicians managing patients with new onset stable angina, based on English national guidelines, introduced through an educational intervention. Isolation of actinomycetes from various soil samples of Ranchi district (Jharkhand) and studies on their antimicrobial activities. This small amount of IL2 was found to be crucial for the observed TRF activity.

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Global environmental impacts of agricultural expansion: the need for sustainable and efficient practices. Regional differences in cerebral noradrenaline turnover in mice withdrawn from repeated morphine treatment and tolerance to the effects of acute morphine. We tested the expression of IGF-1R and calculated the survival in 61 SCLC patients. To determine the maximum tolerated doses (MTD) and the dose-limiting toxicities (DLTs) of the weekly administration of docetaxel and gemcitabine as first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). Change in the disease name for schizophrenia in Japan and its effect on informed consent given by physicians. Evidence will be provided that the protection of the genome integrity in terminally differentiated cells is achieved by different strategies than in proliferating cells. The relative roles of surgery and angioplasty should become better defined.

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