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Polymox (Amoxicillin)
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Polymox

Polymox is acceptable for uncomplicated acute sinus infections; however, many doctors prescribe amoxicillin-clavulanate (Augmentin) as the first-line antibiotic to treat a possible bacterial infection of the sinuses. Polymox usually is effective against most strains of bacteria.

Other names for this medication:
Acimox, Alfamox, Almodan, Amoclen, Amopen, Amoram, Amoxi, Amoxicilina, Amoxicillin, Amoxicillinum, Amoxiline, Amoxisol, Amoxypen, Amurol, Bimoxan, Bristamox, Cipmox, Clamoxyl, Flemoxin, Flemoxon, Galenamox, Gimalxina, Hydramox, Larotid, Lupimox, Moxicillin, Novamoxin, Penimox, Polymox, Raylina, Robamox, Sintedix, Solciclina, Sumox, Tolodina, Utimox, Velamox, Wymox

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Also known as: Amoxicillin

Description

Polymox is one of the best forms of antibiotic available today. It is used to treat infections caused by certain bacteria, including: infections of the ear, nose, and throat (pneumonia, bronchitis); infections of the genitourinary tract; infections of the skin and skin structure; infections of the lower respiratory tract; gonorrhea, acute uncomplicated (ano-genital and urethral infections) in male and females.

Polymox is also used before some surgery or dental work to prevent infection. It is also used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. Polymox may also be used for other purposes not listed here.

Polymox acts by inhibiting the synthesis of bacterial cell wall and stopping the growth of bacteria.

Polymox is available in capsules.

Polymox is usually taken every 8 hours (three times a day). It can be taken with or without food.

The chewable tablets should be crushed or chewed thoroughly before they are swallowed. The tablets and capsules should be swallowed whole and taken with a full glass of water.

Take Polymox exactly as directed. Do not take more or less Polymox or take it more often than prescribed by your doctor. Do not stop taking Polymox without talking to your doctor. To clear up your infection completely, continue taking Polymox for the full course of treatment even if you feel better in a few days. Stopping Polymox too soon may cause bacteria to become resistant to antibiotics.

Dosage

Adults: 1 g PO once daily or 500 mg PO twice daily for 10 days. The American Heart Association (AHA) recommends extended-release Polymox as an alternative to penicillin V for rheumatic fever prophylaxis.

Infants, Children, and Adolescents: 25 mg/kg/dose (Max: 500 mg/dose) PO twice daily for 10 days is recommended by the Infectious Diseases Society of America (IDSA). Alternatively, 50 mg/kg/dose PO once daily (Max: 1 g/dose) for 10 days is recommended by The American Heart Association (AHA) as an alternative to penicillin V. For ear/nose/throat infections in general, the FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Polymox are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Polymox.

Crystalluria, in some cases leading to renal failure, has also been reported after Polymox overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Polymox crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Polymox. Polymox may be removed from circulation by hemodialysis.

Storage

Store this medicine at room temperature, away from heat, light, and moisture.

Side effects

The most common side effects associated with Polymox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Children, infants, neonates, premature neonates.

Polymox has been used to treat infections in infants (3 months of age), including neonates and premature neonates. However, dosages must be modified for these age groups compared to infants (3 months of age) because of incompletely developed renal function. Safety and effectiveness of Moxatag extended-release tablets has not been established in neonates, infants, or children (12 years of age).

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Drinking patterns and social consequences: a study of middle-class adolescents in two private pediatric practices. Next-generation sequencing for genetic testing of familial colorectal cancer syndromes. Cognitive and affective functioning is sensitive to changes in thyroid hormones. Therefore, the distribution of QOPs appears to determine the correct site of osteoclastic development. The thermotropic behavior of multilamellar liposomes prepared from mixtures of distearoyllecithin and sulfatide of definite fatty acid composition, has been studied by DTA calorimetry. Most evidence on brain mechanisms involved in dealing with such tasks comes from neuropsychology. Predictive value of thymidylate synthase expression in resected metastases of colorectal cancer. The opposite strategy is predicted for animals which need to see large, fast images. In this report, we demonstrate that protein transfer of glycosyl-phosphatidylinositol (GPI)-anchored costimulatory molecules into tumor cell membranes could be used as an alternative to gene transfer for tumor immunotherapy.

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The p75 neurotrophin receptor (p75(NTR)) regulates a wide range of cellular functions, including apoptosis, neuronal processes remodeling, and synaptic plasticity. Reproducibility of phase-contrast microscope measurements of percentage motile microorganisms in samples removed from the dorsum of the tongue. Studies on the binding of cortisol-4-14C by human leucocytes in vitro. Quick Fabrication of Large-area Organic Semiconductor Single Crystal Arrays with a Rapid Annealing Self-Solution-Shearing Method. Cardiomyocyte apoptosis has been found in congestive heart failure, but its clinical significance has been difficult to study. Chronic polyradiculoneuropathy is different from acute form mainly by evolution. Late clinical and angiographic followup have revealed satisfactory results and no changes in caliber of vein graft.

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Quantitative analysis of segmental wall motion during maximal upright dynamic exercise: variability in normal adults. This prospective FDR cohort will be a valuable resource for evaluating the relationship between genetic and epidemiologic factors and the development of RA-related autoimmunity. Cardiac output and arterial pressure decreased during bypass, but changed little when extracorporeal flow (EF) was increased from 1/10 to 3/4 of control cardiac output. Five cases that satisfied the criteria proposed by the National Institutes of Health were examined. Physicians counseling parents of infants with persistent crying should recognize the infant characteristics associated with increased crying. Butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) at concentrations of 100 ppm (0.45 and 0.55 mM, respectively) produced a marked leakage of lactic dehydrogenase (LDH) from cultured myocardial and endotheloid cells into the culture medium. A computerized MEDLINE search was conducted of the literature 1981 to 1997. Probe pressure during ultrasound image acquisition causes prostate displacement, which is correlated to the amount of probe displacement from initial contact. Endometrial transplantation as a method of treatment of some forms of amenorrhea and sterility.

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To acquire the most meaningful understanding of human arthritis, it is essential to select the disease model and methodology translatable to human conditions. In 3 patients, exercise provoked a PADBP rise above 30 mm Hg, possibly an evidence of early myocardial contractility disturbance. A retrospective study was carried out to assess the performance of routine ultrasound screening in women with pre-existing diabetes (Types 1 and 2) within a tertiary institution. Total protein extracted from inflamed rat uveal tissue displayed no significant gelatinolytic modulation throughout the time course of EIU. The binding reaction of aminopyrine with microsomal cytochrome P-450 was also modified by cyanide, and an abnormal aminopyrine-induced difference spectrum of microsomes by cyanide, and an abnormal aminopyrine-induced difference spectrum of microsomes appeared when cyanide was added to the reaction mixture. Plasma-Derived Fibronectin Stimulates Chondrogenic Differentiation of Human Subchondral Cortico-Spongious Progenitor Cells in Late-Stage Osteoarthritis. Multiparametric imaging is meant to identify nonreversible lesions and predict on admission the minimum final infarct volume, a strong predictor of outcome.

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