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Nifostin (Azithromycin)

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Nifostin is an antibiotic medication. It is commonly given to children for the treatment of a wide range of bacterial infections targeting the ear, eyes, nose, throat, lungs, skin, and gastrointestinal tract.

Other names for this medication:
Arzomicin, Azadose, Azenil, Azifast, Azimax, Aziphar, Azirox, Azithin, Azithro, Azithrocine, Azithrox, Azitrim, Azitrix, Azitrocin, Azitrolit, Azitrom, Azomycin, Disithrom, Doyle, Fabramicina, Goxil, Gramokil, Inedol, Iramicina, Kromicin, Neofarmiz, Nifostin, Opeazitro, Orobiotic, Respazit, Ribotrex, Ricilina, Tanezox, Toraseptol, Tremac, Ultreon, Vinzam, Zaret, Zifin, Zinfect, Zirocin, Zithrin, Zithromac, Zithrox, Zitrocin, Zitromax, Zival, Zocin

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Also known as: Azithromycin


Nifostin is used to treat bacterial infections in many different parts of the body. It is also used to prevent Mycobacterium avium complex (MAC) disease in patients infected with the human immunodeficiency virus (HIV).

Nifostin belongs to the class of drugs known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, Nifostin will not work for colds, flu, or other virus infections. Nifostin injection may be used for other problems as determined by your doctor.

Nifostin is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Nifostin is used in certain patients with the following medical condition: Trachoma (treatment).


You should take Nifostin orally with a full glass of water 1 hour before or 2 hours after food. Take Nifostin at the same time every day. Nifostin treats different types of bacterial infections and can be used both by adults and by children. For children: The dosage is dependent upon the child's weight. In treatment of otitis media, take Nifostin for 1-5 days. For adults: To treat pneumonia or throat/tonsil infection, the recommended dose is two 250 mg tablets on the first day and then one 250 mg tablet once a day for 4 more days. For the prevention of MAC (mycobacterium avium complex), the recommended dosage of Nifostin is 1,200 mg per week. For the treatment of skin or infections, the recommended dosage is two 250 mg tablets on the first day and one 250 mg tablet for another 4 days.


If you overdose Nifostin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Nifostin overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.


Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Nifostin Tablet.

Side effects

The most common side effects associated with Nifostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure have been reported, some of which have resulted in death. Discontinue Nifostin immediately if signs and symptoms of hepatitis occur.

The presence of other medical problems may affect the use of Nifostin. Make sure you tell your doctor if you have any other medical problems, especially: allergy to any macrolide and ketolide antibiotic or liver disease with prior Nifostin use or bacteremia (blood infection) or cystic fibrosis or infections, nosocomial or hospital-acquired or weak immune system or bradycardia (slow heartbeat) or hypokalemia (low potassium in the blood) or hypomagnesemia (low magnesium in the blood)

Not recommended in patients with these conditions: congestive heart failure or diarrhea or heart disease or Heart rhythm problems (e.g., prolonged QT interval), history of or Myasthenia gravis (severe muscle weakness).

Use with caution. May make these conditions worse: kidney disease, severe or liver disease. The effects may be increased because of slower removal of the medicine from the body.

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