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Momicine

Momicine is an antibiotic. It's widely used to treat chest infections such as pneumonia, infections of the nose and throat such as sinus infection (sinusitis), skin infections, Lyme disease, and some sexually transmitted infections.

Other names for this medication:
Azicin, Azilide, Azimakrol, Azinix, Azinom, Azitrotek, Azitrox, Azrolid, Aztrin, Disithrom, Doromax, Goxil, Magnabiotic, Medimacrol, Neblic, Orobiotic, Penalox, Sitrox, Texis, Triamid, Trozocina, Vectocilina, Zedd, Zentavion, Zimax, Zithrox, Zitrocin, Zitrofar

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Omnicef, Avelox, Suprax, Chloromycetin, Cefixime

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Also known as: Azithromycin

Description

Momicine (Momicine tablets and Momicine for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Momicine has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Momicine is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Momicine, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Momicine is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Momicine for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

You should take Momicine orally with a full glass of water 1 hour before or 2 hours after food. Take Momicine at the same time every day. Momicine treats different types of bacterial infections and can be used both by adults and by children. For children: The dosage is dependent upon the child's weight. In treatment of otitis media, take Momicine for 1-5 days. For adults: To treat pneumonia or throat/tonsil infection, the recommended dose is two 250 mg tablets on the first day and then one 250 mg tablet once a day for 4 more days. For the prevention of MAC (mycobacterium avium complex), the recommended dosage of Momicine is 1,200 mg per week. For the treatment of skin or infections, the recommended dosage is two 250 mg tablets on the first day and one 250 mg tablet for another 4 days.

Overdose

If you take an overdose of Momicine you should visit your doctor or health care provider immediately. Symptoms of Momicine overdosage include discomfort in the stomach, diarrhea, retching and nausea.

Storage

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Momicine Tablet.

Side effects

The most common side effects associated with Momicine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Momicine if you are allergic to azithromycin and other macrolides. Do not take Momicine at the same time as taking antacids containing magnesium or aluminum. Exercise caution with Momicine if you are pregnant or are a nursing mother. If you have liver or kidney disease, Long QT syndrome or heart rhythm problems, consult your doctor before taking Momicine. Exercise caution if you are also taking cyclosporine (Neoral, Sandimmune), anticoagulants ('blood thinners') such as warfarin (Coumadin), terfenadine (Seldane), digoxin (Lanoxin), dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar), phenytoin (Dilantin), medications that suppress your immune system, nelfinavir (Viracept). Exercise caution with Momicine usage if you are allergic to erythromycin (E.E.S., E-Mycin, Erythrocin), dirithromycin (Dynabac), clarithromycin (Biaxin) or azithromycin. Avoid excessive exposure to sunlight as Momicine makes skin sensitive to sunlight. Take care to protect skin from the sun. It can be dangerous to stop taking Momicine suddenly.

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Female BALB/c mice were immunized with human melanoma (Mewo) cells containing ganglioside GD3 as a surface antigen. Alpha(1D)-adrenergic receptor insensitivity is associated with alterations in its expression and distribution in cultured vascular myocytes. Here, we present data showing that three ALPs, 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine, hexadecylphosphocholine, and the novel compound octadecyl-(1,1-dimethyl-piperidinio-4-yl)-phosphate (D-21266) induce time- and dose-dependent apoptosis in the human leukemia cell lines U937 and Jurkat T but cefpodoxime 100 mg vidal not in normal vascular endothelial cells. These cells possess a uniquely limiting mitochondrial aconitase (m-aconitase) that minimizes citrate oxidation and thus permits citrate to accumulate. On review of the 100 chest radiographs, no embolized seeds were found. Endoscopy and routine duodenal biopsy were in use throughout the study period. Dose levels of 30 mg/kg and higher removed 93 per cent of mucosal stages of Trichonema spp., while doses of 60 mg/kg removed 83 per cent and 89 per cent of the migrating larvae of S.

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Integrating diet therapy and dietary counseling: an alternative education technique. Natural history of acute regional myocardial ischaemia revealed by infrared thermography in the canine heart. The role of T suppressor cells in the induction of specific unresponsiveness. Bayley developmental assessment showed a mental age of 12 months and a motor age of 9 months. The results of EBCT scans should be interpreted in the light of other available evidence, including such information as age, sex, the presence of risk factors for coronary disease, and the results of other tests such as ECG stress tests and imaging procedures. The synthesis of phosphatidylcholine by adult rat lung alveolar type II epithelial cells in primary culture. Parameters of acute pancreatitis, such as serum amylase (AMS) and plasma myeloperoxidase (MPO) activities, were assayed using spectrophotometry. Owing to the highly conserved nature of its active site, Influenza B virus neuraminidase (NA) has emerged as a major target for the design of novel anti-influenza drugs. Thrombophilic familial protein S deficiency is known to be amplified by estrogen replacement therapy. Clinical characteristics and treatment outcomes of microscopic polyangiitis combined with autoimmune hemolytic anemia.

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Separation and identification of phosphatidylcholine regioisomers by combining liquid chromatography with a fusion of collision-and ozone-induced dissociation. To study the effects of melatonin on primary rat cortico-hippocampal neurotoxicity induced by amyloid beta-peptide 25-35. Treatment with estradiol or progesterone alone did not markedly influence the level of uterine adrenergic transmitter, whereas combined estradiol and progesterone administration caused a clear-cut reduction in uterine noradrenaline. To determine if SV5 could be used as a vector for controlled killing of tumor cells, a recombinant SV5 (rSV5-TK) was constructed to encode the herpes simplex virus thymidine kinase (TK) gene. The virome is dominated by rare genes, many of which might be contained within virus-like entities such as gene transfer agents. One polypeptide derived from the constant region was separated from the main component by high performance liquid chromatography. A table is described with which the mobility within the grasping area of each finger can be tested and documented without joint measuring.

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Recognition of hereditary nonpolyposis colorectal cancer (HNPCC)-related endometrial carcinoma from sporadic carcinoma by histologic features as compared with colonic cases. Increased Ald might be an important pathogenesis for AF formation and progression, spironolactone and perindopril could attenuate atrial remodeling and improve atrial function by reducing plasma and tissue Ald levels in this model. The experiments showed that subcutaneous injections of morphine (0.5-8 mg/kg) induced CPP in a dose-dependent manner in mice. The aim of this paper is to review the different means of achieving foetal malnutrition and its consequences even for a next generation, in animal models and to identify key area for further research. Minimal access thyroid surgery, using various techniques, is increasingly being reported. We have shown that the treatment of astrocytes with a mixture of Tat and cytokines leads to a respiratory burst that is abrogated by apocynin, an NADPH oxidase inhibitor. The tablet disintegration was delayed between 5 min and more than 1h in the simulated gastric fed medium compared to a simple buffer. A fragment of the PLU-1 cDNA was identified by differentially screening a fetal brain library with cDNAs prepared from ce-1 cells (a human mammary epithelial cell line overexpressing c-ErbB2) treated or untreated with the antibody 4D5, which inhibits c-ErbB2 phosphorylation. Upon lysis of infected cells at 46 h, the MOMP was rapidly cross-linked, and infectious EBs were released.

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