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Metronidazole

Metronidazole eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Aldezol, Amebidal, Aminidazole, Biozyl, Colpofilin, Deflamon, Filmet, Flagenase, Flagicure, Flagystatin, Flazole, Fortagyl, Geloderm, Ginerella, Imizine, Klion, Medamet, Metrin, Metrol, Metronidazole, Metrozin, Metrozol, Micogyl, Nalox, Nizole, Noritate, Orogyl, Polibiotic, Promuba, Protozol, Rodogyl, Rosazol, Rupezol, Suanatem, Tolbin, Trichostatic, Tricozyl, Unigyl, Vertisal, Wingyl

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Description

Metronidazole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Metronidazole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the pres- ence of the trichomonad be reconfirmed by appro- priate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

Single oral doses of Metronidazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Metronidazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Metronidazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Metronidazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity. Metronidazole Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Metronidazole Tablets is contraindicated during the first trimester of pregnancy.

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Characteristics of the chemotactic response of neoplastic cells to a factor derived from the fifth component of complement. The aim of this study was to analyze our results using a modular endoprosthetic replacement system (MUTARS) for bone tumors of the proximal humerus. TonB interacts with nonreceptor proteins in the outer membrane of Escherichia coli. Review of the literature reveals that such extensive hernias are rare and that their surgical repair is often difficult because of loss of domain. The procedure yields a highly pure myosin devoid of any obvious contaminants, such as tropomyosin and actin. Descriptive statistics were calculated for variables on characteristics by age group. Shared medical equipment and blood-contaminated gloves may constitute a potential route of transmission. The effects of volume loading on a nociceptive reflex, arterial blood pressure and heart rate were studied in spontaneously hypertensive rats (SHRs), Wistar Kyoto normotensive rats (WKYs) and the F1 offspring of a SHR x WKY cross. We used clinical bradykinesia and functional capacity scales, an extensive prefrontal battery and a computerized paradigm of reaction time.

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Improvements to parks may not automatically result in increased use and physical activity, especially when programming decreases. Forty-eight-hour fasted or fed male rats were injected with recombinant rat GH via the portal vein. However, despite documented beneficial effects of RAAS inhibitors in diabetic patients with nephropathy, reversal of the progressive course of this disorder or at least long-term stabilization of renal function are often difficult to achieve, and many patients still progress to end-stage renal disease. These studies suggest that measurement of plasma L-dopa may be useful in the diagnosis of melanoma. This suggests a high androgen and low estrogen synthesis during the period of delayed ovulation.

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We investigated the sensitivity of porcine endogenous retrovirus (PERV) produced from Gal-null and Gal-positive pig cells to inactivation by purified NAb and human serum. CLA reduces body fat accumulation in animal models and has been ascribed significant effects on lipid and glucose metabolism. The findings also suggest that any factors that induce repeated or continuing bladder spasms may contribute to progressive dilatation of the upper urinary tract. Systemic administration of autologous, alloactivated helper-enriched lymphocytes to patients with metastatic melanoma of the lung. Tributyrin- and Rhodamine B-based functional screen of a Bacillus subtilis genomic library led to the identification of a potential lipolytic gene. After the fourth experimental week, however, there was no significant difference between the group treated by UV-B alone and the combination group. Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain.

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Botanical identification of several Echinochloa biotypes collected in Spanish rice fields with control failures of cyhalofop-butyl. The brain weight was 1110 g and the outer surface of the brain was normal. Direct genetic analysis of chorionic villi or amniotic fluid cells is feasible, fast, and specific, and can be regarded as the method of choice for prenatal diagnosis in urea cycle disorders. Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: double-blind, randomized, controlled clinical trial. Problems associated with the use of drugs and alcohol among young students. At the end of 30 days, all groups underwent auditory brainstem response testing after administration of intraperitoneal urethane anaesthesia.

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The purpose of this report is to evaluate evidence for linkage of IgE with polymorphic genetic markers in the candidate region of 5q in four large pedigrees originally selected for studies of atopy. Despite use in many countries of tapered methadone for detoxification from opiate, the evidence of efficacy to prevent relapse and promote lifestyle change has not been systematically evaluated. Feasibility of computerized scheduled gradual reduction for adolescent smoking cessation. Intensity of MR contrast enhancement does not correspond to clinical and electroneurographic findings in acute inflammatory facial nerve palsy. A hypothesis is detailed suggesting that all polypeptides which enter the cilium, both membrane and axonemal, do so in association, first, with cytoplasmic vesicles which exocytose adjacent to the ciliary basal body, and then with the ciliary membrane. However, around 4 to 6 sessions are required to obtain significant lasting hair removal. Accumulating evidence supports that dysregulation of adipose lipolysis and liver de novo lipogenesis (DNL) plays a key role in driving hepatic steatosis.

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Pathway-Based Genome-wide Association Studies Reveal That the Rac1 Pathway Is Associated with Plasma Adiponectin Levels. The physiological significance of primary cilia is underscored by the fact that defects in assembly or function of these organelles lead to a range of severe diseases and developmental disorders. Correlates of memory function in community-dwelling elderly: the importance of white matter hyperintensities. The observed concentration-response curve (CRC) of a ray was compared with that predicted by CA or IA model to qualitatively assess the toxicity interaction of the mixture ray. Effect of fluoride on glycerol production in rat adipocytes in vitro. Fc and iC3b receptors are involved in various biological functions of phagocytic cells, such as immune adherence and phagocytosis of opsonized particles, degranulation and superoxide generation.

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