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Magnabiotic (Azithromycin)

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Magnabiotic is an antibiotic medicine that is used for the treatment of bacterial infections of various parts of the body like ears, throat, lungs, skin, soft tissues, urinary tract, etc. This tablet contains azithromycin as its active component.

Other names for this medication:
Azicine, Azimac, Azimax, Azimed, Azimit, Aziphar, Azithrocin, Azitral, Azitrin, Azitrom, Azitromicina, Azrolid, Aztrin, Bezanin, Binozyt, Cinalid, Clearsing, Ericiclina, Macromax, Medimacrol, Naxocina, Sitrox, Talcilina, Toraseptol, Tromix, Ultrabac, Vectocilina, Zetamax, Zitrolid

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Also known as: Azithromycin


Magnabiotic (Magnabiotic tablets and Magnabiotic for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Magnabiotic has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Magnabiotic is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Magnabiotic, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Magnabiotic is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Magnabiotic for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.


Use Magnabiotic as directed by your doctor.

Take Magnabiotic by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

Do not take an antacid that has aluminum or magnesium in it within 1 hour before or 2 hours after you take Magnabiotic.

Magnabiotic works best if it is taken at the same time each day.

To clear up your infection completely, use Magnabiotic for the full course of treatment. Keep using it even if you feel better in a few days.

Ask your health care provider any questions you may have about how to use Magnabiotic.


Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Magnabiotic overdose may include nausea, vomiting, diarrhea, and stomach discomfort.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Magnabiotic are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Many drugs can interact with Magnabiotic. There is a partial list. Tell your doctor if you are using: arsenic trioxide (Trisenox); cyclosporine (Neoral, Sandimmune); pimozide (Orap); tacrolimus (Prograf); theophylline (Theo-Dur, Theolair, Theochron); warfarin (Coumadin, Jantoven); another antibiotic, especially clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam); an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), or desipramine (Norpramin); anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam); cholesterol-lowering medicines such as lovastatin (Mevacor), atorvastatin (Lipitor), or simvastatin (Zocor); ergot medicine such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray); heart or blood pressure medication such as digoxin (Lanoxin, Lanoxicaps), diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others; heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace); HIV medicines such as nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Invirase); medicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran); medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon); migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig); narcotic medication such as methadone (Methadose, Diskets, Dolophine); a sedative or tranquilizer, such as alprazolam (Xanax), diazepam (Valium), midazolam (Versed), or triazolam (Halcion); or seizure medicine such as carbamazepine (Carbatrol, Tegretol) or phenytoin (Dilantin).

This list is not complete and there are many other drugs that can interact with azithromycin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

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Electrophoretic mobility-shift assays yielded an apparent binding affinity of H-NS binding to curved DNA of approximately 1 microM, whereas binding to rpoS mRNA or DsrA RNA was approximately 3 microM. In addition, we studied the efficacy of deferasirox alone or combined with LAmB in treating immunocompromised mice infected with A. The potential usefulness of these monitors in various clinical situations has been described in case studies. The local changes were evaluated by sequential radiograph, manual palpation, histomorphology, and microradiography. Specifically, we found that alcohol consumption produces a long-lasting enhancement of channel activity and persistent alterations of neuronal morphology in a part of the brain (DMS) that controls alcohol-drinking behaviors. Ultrastructural analysis of interneuronal syncytial perforations. Before treating the anterolateral rotatory instability, it is necessary to identify and treat other commonly associated abnormalities.

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In this respect, this modality is superior to arteriography as a means of evaluating arteriogenic impotence. Probiotic treatments using human-derived microbes, either prophylactic or curative, can be tested within the model. Twelve patients treated with aminohydroxybutylidene diphosphonate and 16 patients treated with dichloromethylene diphosphonate were assessable and were followed up for one to six months. A20 inhibits toll-like receptor 2- and 4-mediated interleukin-8 synthesis in airway epithelial cells. Reducing the costs of management appears an easy target for those seeking to generate savings or to promote better spending in the National Health Service (NHS). In soilless plant cultures, PpDGB-driven profile changes could be observed from the 5th day after the initial treatment. In male pentothal-anesthetized Wistar rats (body weight 200-250 g) ischemia of the right kidney was obtained by clamping (clamp diameter 0.15 mm) the ipsilateral renal artery for varying periods of time (10 min to 6 h) followed by removal and instant freezing of the kidney in isopentane at -165 degrees C and subsequent freeze-substitution in alcohol. Double staining and flow cytometry were used to assay Fc gamma-receptor and beta 2-integrin expression with respect to the mPR3 phenotype. Excision and palatoplasty were performed conjunctively with excellent results. The levels of IL-4, IL-5 and IL-13 declined only in the IT group.

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Increased levels of oxidative stress have been reported in the cerebrospinal fluid (CSF) of patients with various neurodegenerative disorders. Identifying the factors that affect length of stay for patients hospitalized for cardiac surgery and ways to safely and effectively shorten stays could have significant impact on healthcare costs. Actions by actin: reciprocal regulation of cortactin activity by tyrosine kinases and F-actin. Reaction conditions which promote the heme-dependent peroxidase activity of prostaglandin H synthase appear to stimulate the heme-dependent cyclooxygenase activity also present in the synthase, even though the cyclooxygenase requires hydroperoxide for activity. Low endogenous levels of dehydroepiandrosterone (DHEA) and/or its sulfoconjugated derivative DHEA-S have been associated with diseases such as lupus, cancer, and diabetes.

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Twice-weekly, directly observed treatment for HIV-infected and uninfected tuberculosis patients: cohort study in rural South Africa. The dynamics of ponds inhabited by Cyclopidae has been surveyed as far as their densities and their species are concerned. Consistent clinical assignment for nursing students compared to multiple placements. Apoptosis was measured by flow cytometry using annexin V/propidium iodide to determine early and late apoptosis. Control cultures identified in the hospital building water reservoirs the presence of the organism. A total of 14 protein spots showed reproducible changes in expression of at least 1.5-fold when compared to the control and showed a similar expression pattern in both treatments. The role of parental behaviour in the development of food preferences is considered. Factors believed to influence this production choice decision are the cost savings that can be expected from economies of scale or increased competition, the willingness of local officials to trade control for such cost savings, and the political incentives and obstacles to contracting out.

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Therefore, subject-specific finite-element (FE) analysis of a group of rat hearts was implemented for extrapolating a set of initial DT-MRI to the rest of the cardiac cycle. The presence or absence of sperm was found to correlate poorly with the time since intercourse. The effect of a change of acoustic impedance on the TEOAEs, induced by filling the external canal with helium what if i miss one dose of flagyl or sulphur hexafluoride gas, is measured in a group of normal hearing subjects. Clinical features, management and in-hospital outcome of ST elevation myocardial infarction (STEMI) in young adults under 40 years of age. The nucleoside analogue gemcitabine displays therapeutic effects mainly against breast, ovarian and pancreatic cancer. To determine whether autoimmunity against fibrinogen can mediate inflammatory arthritis, we immunized a variety of common mouse strains with fibrinogen and found that DBA/1 and SJL mice developed an inflammatory and erosive arthritis. The causes and prevention of pulmonary hemorrhage in the newborn. The binding of Sema4D to Plex-B1 can trigger the activation of Met tyrosine kinase, thereby promoting cell dissociation and invasive growth.

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The diminution of methamidofos, malathion, and methiocarb in different crops grown in greenhouses has been studied, including the presence of metabolites such as malaoxon, methiocarb sulfoxide, and methiocarb sulfone. Cervical spine x-ray films demonstrated massive anterior degenerative osteophytic spurs between C-3 and C-7. However, the role of respiratory epithelial cells in the production of IL-8 in HP is unknown. By decelerating and stopping the ion pulse of reserpine and substance P from an ESI source in the path of the droplet beam, about 10(4) ion-doped droplets (one ion per droplet) can be recorded, corresponding to a pickup efficiency of nearly 1 out of 1000 ions. In addition changes in PRA, aldosterone, AVP and ANF did not correlate with WI-induced changes in MAP. Employment status, employment conditions, and limiting illness: prospective evidence from the British household panel survey 1991-2001. We report a case of button battery in the nose of a 4-year-old boy presenting with unilateral nasal discharge, and necrosis in the septum and turbinate of the right nasal cavity. Hydrogenation studies involving halobis(phosphine)-rhodium(I) dimers: use of parahydrogen induced polarisation to detect species present at low concentration.

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Level of phosphorylated tau at paired helical filament-1 (PHF-1) epitope was elevated at 1 h, peaked at 6 h, and then decreased at 12 h and 24 h after injection of wortmannin 10 mumol/L. k-means), which group open reading frames (ORFs) based on similar expression levels, are deficient unless the temporal pattern of the expression levels of the ORFs is taken into account. From electric acoustic stimulation to improved sound coding in cochlear implants. ABMT with bcr/abl AS-ODN purged graft can result in quite long duration of MCR and prolonged CP in some patients with CML. Costs and effectiveness of partner counseling and referral services with rapid testing for HIV in Colorado and Louisiana, United States. Evaluation of an epidemic of sporotrichosis in cats: 347 cases (1998-2001).

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There was a significant difference in the plasma FDP levels between the study group and the control group. We have compared the results of the fit to the SEFs of Choung and Fung and Holzapfel et al. The senescence-associated beta-galactosidase histochemistry assay, adapted for use in the primate posterior pole, showed staining of RPE cells in older eyes. The association of the MR with p300, a transcriptional coactivator of GATA4 required for hypertrophic responses, was examined. Activation-induced cell death (AICD) plays a critical role in the maintenance of homeostasis and peripheral tolerance in the immune system, and is mediated by Fas ligand (FasL) expression and the interaction between Fas and FasL. Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani and Mycobacterium tuberculosis were used as test organisms in the in vitro assays. Multicenter trial on the efficacy of HBIG and vaccine in preventing perinatal hepatitis B. The importance of standard parameters is emphasized for the applications of low intensity lasers in biology and medicine.

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Methods of detecting ditolylmethane and the separate determination of ditolylmethane and styrol in their simultaneous presence in the air. Serological investigation on cattle vaccinated with a killed Brucella abortus strain 45/20 adjuvant vaccine. L-tryptophan induces expression of collagenase gene in human fibroblasts: demonstration of enhanced AP-1 binding and AP-1 binding site-driven promoter activity. This mechanism is originated by a translocation between the Y chromosome and one of the autosomes (A7). However, it is possible that this type of developmental defect could occur because of regionalized abnormalities in cellular function and proliferation as occurs in regional odontodysplasia. To evaluate the association of prostatic urethral angle (PUA) with bladder outlet obstruction (BOO) index in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH). In addition, some of the clones appear to encode conserved antigens that are recognized by sera from mice immunized with L. Patients with intra-abdominal testis underwent laparoscopic orchiopexy or orchiectomy. Since the authors began doing liposuction in 1989, they have had several diabetic patients whose insulin or oral diabetic needs have been substantially reduced after noroxin 400 mg fiyat liposuction. Genetically manipulated vectors of human disease: a practical overview.

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Angulated projections are standard in conventional radiography of the cervical spine, but rarely used in magnetic resonance imaging (MRI). To examine glutathione S-transferase M1 (GST M1) gene polymorphism and male infertility in Taiwanese patients with varicocele, 80 young male patients with varicocele (group 1), 62 young male patients with subclinical varicocele (group 2) and 60 normal young males (group 3) were recruited in this study. The reorientation of basal bodies occurs during the beginning of the coordinated beating cycle of the cilia. Both the stimulatory and the inhibitory effects depend on the sustained presence of estrogen. Consistent with the increases in serum ALT activity, histopathologic examination revealed centrilobular necrosis with marked neutrophilic accumulation only in livers of cost of cleocin mice treated with LPS/APAP or with reovirus/APAP. A case of recurrent paroxysmal sneezing in an adolescent girl is reported with a review of the literature.

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The therapy only ensued on intensive care conditions and a spontaneous closure of the fistula was observed in 7 patients, in 2 patients closure ensued after relaparotomy and parenteral hyperalimentation the time before. Two other groups of piglets were treated with dexamethasone (40 mg) alone or with multiple injections of ondansetron (7 injections at 3.5 mg/kg), respectively. To study the antitumor immune effects of ovarian carcinoma vaccine modified with human B7-1 and IFN-gamma genes, we constructed the bicistronic retroviral vector pLXSN, encoding human B7-1 and IFN-gamma. Effectiveness of an ethics course delivered in traditional and non-traditional formats. The effects of cultivation temperature, pH of the culture medium, aeration rate and agitation speed on the production of cholesterol oxidase (CholOx) by the test organism were examined. One difficulty in studying molecular changes of tumours has been the inability to isolate DNA and RNA from a homogeneous cell population. Radiography of injured arms and legs in eight accident and emergency units in para que sirven las pastillas flagyl 500 mg England and Wales. To assess the effectiveness of the simplified medication adherence questionnaire (SMAQ) in identifying non-adherent patients. In the mid-frequency region, around 1 kHz, the organ of Corti with inner and outer hair cells was often conserved while in the lower basal turn, representing frequencies above 3 kHz, the organ of Corti was atrophic and replaced by thin cells.

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In the first investigation, sewage sludge was co-digested with industrial waste from potato processing. Vitellogenin receptors: oocyte-specific members of the low-density lipoprotein receptor supergene family. However, the concentration of thermogenin in isolated mitochondria remained unchanged. The measured data showed that the induced voltage in some frequency was prominent, for example over 2V. The presence of the SpAb was shown to prevent sperm penetration of cervical mucus, to inhibit sperm-zona pellucida interaction, and to interfere with the sperm-egg fusion. So the maneuver of lumbar decompression with fusion is a better choice. Quantitative investigation of bone microvascularization from 3D synchrotron micro-computed tomography in a rat model. It is concluded that the functional disturbance of reflex vasomotion in EAUN is not accompanied by specific ultrastructural lesions nor could neuronal components be immunologically implicated in the disorder. In immunodiffusion tests, F4B mAb produced a stable precipitin band with RRg, while the band developed between the mAb and RRd/TCAh in the cold disappeared when incubated at room temperature.

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This study reinforces the need for gender- and culture-specific approaches to studying the factors that influence smoking among adolescents. The fewest changes in coagulation factors and inhibitors occurred among women taking low-dose estrogen combined with levonorgestrel, indicating that progestogen used in combination modifies the estrogenic effects on the coagulation system. Vascular surgical repair succeeded in 130 to 180 patients, but graft loss occurred in 20 cases and recurrent stenosis in 11. Furthermore, the level of spontaneous induction was similar to that obtained with mitomycin C. Like other antihypertensive agents, prazosin should be given with a diuretic. Versatile description languages such as the Unified Modeling Language (UML) are commonly used in software engineering across different application domains in theory and practice. Psychometric findings in hyperpressure, during the respiration of mixtures with various nitrogen concentrations. Functional changes in the kidneys during the course of tuberculous pyelone-phritis. With this approach we identified a mutation, L346P, which in association with the severe mutation delta F508 or 1677delTA, confers a mild and atypical presentation. The aim of this research was to evaluate the risk factors for new and chronic subclinical intramammary infections (IMI) using the monthly somatic cells count of dairy cows.

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