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Macrobid

Macrobid is used for the treatment of various infections in the body like infections of the throat, sinus, skin, soft tissue, chest (infection of lungs and windpipe). It is also used in the treatment of ulcers in the intestine caused by bacteria known as helicobacter pylori. It is also used for pneumonia as well as for skin infections.

Other names for this medication:
Aeroxina, Althromicin, Binoclar, Cidoclar, Clabact, Clacine, Clarimax, Clariva, Clariwin, Clarix, Clarogen, Claromycin, Clarosip, Clatic, Cleanomisin, Egelif, Ezumycin, Geromycin, Helozym, Infex, Kalecin, Karid, Klarimax, Klarith, Klarithran, Klaritpharma, Kleromicin, Krobicin, Laromin, Lyoclar, Odycin, Onexid, Rocin, Rolacin, Synclar, Taclar, Vikrol, Zeclar, Zeclaren

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Also known as: Clarithromycin

Description

Macrobid (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Macrobid works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Macrobid Filmtab and Macrobid Granules are recommended as the primary agents. Macrobid Filmtab and Macrobid Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Macrobid is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Macrobid therapy should continue if clinical response is observed. Macrobid can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store Macrobid at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Macrobid out of the reach of children and away from pets.

Side effects

The most common side effects associated with Macrobid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Macrobid if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao). Do not take Macrobid if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Macrobid if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane). Do not take Macrobid if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome". Try to be careful with Macrobid usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Avoid consuming alcohol. It can be dangerous to stop Macrobid taking suddenly.

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Treatment of vascular retinal disease with pentoxifylline: a controlled, randomized trial. Tryptic peptides from the two proteins are substantially different, which suggests that there are major differences in their sequences. The affinity of IC binding to E-CR1 was reduced after cleavage of CR1-bound C3b-IC to iC3b-IC by factor I. The annotations for each Fugu scaffold are computed, stored and made publicly available. We have analyzed the functional state and the quaternary structure of the SecYEG translocase by employing cross-linking and blue native gel electrophoresis. Together with water and carbon dioxide plants require 14 essential mineral nutrients to finish their life cycle.

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Studies of temporomandibular joints in children following pelvic delivery. This meta-analysis suggests that plasma MMP-9 concentrations measured 3 months after EVAR are higher in patients that have an endoleak. Among the elderly female population with an episode of PAF, obese women seem to have greater risk for the perpetuation and the stabilization of this arrhythmia due to the enlargement of their atrial size. The increments in infant weight and height in the 3 groups were within the normal range for Egyptian infants. Re: McArdle et al: Early enteral feeding of patients with major burns. Furthermore, 10 health centres out of 15 had adopted the population-based practice, which requires different working methods compared to the old routines. Single pulse waveforms of Taser X26 and Aegis MK63 devices were measured using a resistive load. Iliac bone graft harvest using the percutaneous hollow needle technique results in less blood loss, decreased postoperative pain, and shorter hospital stays compared with the open technique.

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To determine whether postal prompts to patients who have survived an acute coronary event and to their general practitioners improve secondary prevention of coronary heart disease. In this work, the HOMO-LUMO gap of graphene, Ti- or N-doped graphene is investigated by DFT methods. Systolic arterial pressure (SAP) and heart rate (HR) were measured indirectly during 24-hour periods at 3-4 hour intervals. E-cadherin expression in canine mammary carcinomas with regional lymph node metastases. From the newest oral antidiabetics this review tries to emphasize the most important basic pharmacological properties, mechanism of action, therapeutic use. At appropriate doses NGF has no significant side effects in humans. Full term delivery following cryopreservation of human embryos for 7.

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A controlled antibiotic release system to prevent orthopedic-implant associated infections: An in vitro study. Although there are little available data about the frequency of lactase persistence in northern Chinese populations, we compared the allele frequencies with the phenotype frequencies that have been published previously. The study was performed in order to assess and compare the degree of the sensitizing capacities of these chemically related substances. Growth inhibition of Chlorella induced by 3-amino-1,2,4-triazole, and its reversal by purines. Here we review biochemical, genetic, and epigenetic considerations in succinate dehydrogenase loss and present leading models and mysteries associated with this fascinating and important tumor. LPC induced interferon-gamma (IFN-gamma) secretion in peripheral blood mononuclear leucocytes from healthy blood donors. Our experience of this operation and prolonged follow-up of patients, however, confirm that it does not increase risk of persistent or recurrent HPT if a strict selection protocol is observed. Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility. Specificity was also tested against crayfish tissue and some known parasites and bacteria infecting crayfish.

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It was concluded that there is no clinical evidence for increasing the dose of HMG on the day of antagonist administration. Sampling of plasma in the morning and afternoon for up to 12 consecutive days in sighted SCN-lesion rats reveals continuously low luteinizing hormone levels. Twenty-two patients of SARS were randomly selected and paired according to such controlling factors as age, sex and profession into 11 couples. We found that both exogenous NO as well as endogenously produced NO via adenoviral inducible NO synthase gene transfer protected hepatocytes from tumor necrosid factor (TNF) alpha plus actinomycin D (TNFalpha/ActD)-induced apoptosis. A long-term evaluation of alternative treatments to replacement of resin-based composite restorations: results of a seven-year study. The findings showed that acupuncture of voice-related acupoints could bring about improvement in vocal function and healing of vocal fold lesions. Nattokinase (NK), a bacterial serine protease from Bacillus subtilis var. Calcium ionophore A23187 induction of spermidine/spermine N1-acetyltransferase activity in bovine lymphocytes. To evaluate the role of genes from the swine isolates in their pathogenesis, reverse genetics-generated reassortants between the swine human-like H3N1 virus and the seasonal human H3N2 virus were tested in pigs.

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We will review these treatments, their toxicities and how these targeted agents have impacted on mRCC. Studies of pulmonary tuberculosis in persons above fifty years of age. This review has demonstrated needle acupuncture to be of short term benefit with respect to pain, but this finding is based on the results of 2 small trials, the results of which were not able to be combined in meta-analysis. Older adults also suggested a redesign of the interface so that less sophisticated dexterity and motor functions are required. There has been steady progress in the computational analysis of transcription control regions, but current methods of predicting the gene regulatory features of noncoding sequences are still not accurate enough to be useful in automatic genome annotation. In summary, CYP2D6 was found to be the primary P450 responsible for the formation of the major oxidative metabolite of atomoxetine, 4-hydroxyatomoxetine. Today, problems with continuous and localized delivery of specific neurotrophins or combinations thereof into the nervous system appear to be the most important obstacle for more widespread clinical application.

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An unprecedented CoA transferase catalyzes the intramolecular transfer of the CoA moiety to the C4 carboxyl group of mesaconate. Accuracy and predictability of photorefractive keratectomy for astigmatism correction. The techniques of plant improvement have been evolving with the advancement of technology, progressing from crop domestication by Neolithic humans to scientific plant breeding, and now including DNA-based genotyping and genetic engineering. It is released in the extracellular space from HIV-1-infected cells and accumulates in the tissues of patients, even in those successfully treated with highly active antiretroviral therapy. Levels of respiratory gases and indicators of acid-base status in capillary blood analysis in premature infants and infants small for gestational age. The term frailty is used to describe older persons at high risk for adverse health outcomes. The two alternative orientations designed, reduced the constraints for chemical synthesis that depends on the nanosurface to be functionalized.

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Pituitary apoplexy after combined test of anterior pituitary function. Four other pulmonary microsomal polypeptides were characterized and preliminary evidence suggested that they represent unique isozymic forms of P-450 with three of them being related to P-450b. Structure and function of the erythrocyte membranes in healthy newborn infants in the 1st days of life. In this paper, it is demonstrated that T-helper (Th) cell activity for the antibody response to TD antigen is impaired, while other cellular immune responses, e.g. The WT together with AI constitutes a feature extraction engine for localizing the first positive peak and negative valley and hence relative amplitudes. Carnitine protection against adriamycin-induced cardiomyopathy in rats. Clindamycin and gentamicin were administered intravenously after obtaining blood cultures.

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Modification of capillary electrophoresis (CE) capillaries by poly(hydroxyethyl methacrylate) (poly(HEMA), poly(diethylene glycol monomethacrylate) (poly(DEGMA) and poly(triethylene glycol monomethacrylate) (poly(TEGMA), was studied. Unilateral hip excision arthroplasty in lambs resulted in osteochondrosis developing in distal tibiae and metatarsi of the contralateral pelvic limb. In asthma inflammatory cells, particularly eosinophils, migrate into the pulmonary tissue and airway lumen by means of adhesion molecules expressed on resident tissue cells--that is, fibroblasts--and become activated by cytokines and adhesive interactions. By contrast, relocation of calsequestrin to the lumen of the network SR was observed to a variable degree in chemically fixed, suprax antibiotic class ethanol-dehydrated, and Lowicryl-embedded tissue. For A cells there is a linear relation between the size of the peripheral axon and the conduction velocity of the impulses carried by these axons, but the confidence limits are wide. The effect of androgen deprivation on NE differentiation and tumor cell proliferation in the CWR22 model of human CaP was determined by immunohistochemical analysis of the NE cell marker synaptophysin and the cell proliferation marker Ki67. The subjects attended the program for one academic year, on the average.

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Regeneration of rat gastrocnemius muscle after X-ray radiation, mechanical trauma and prolonged infrared laser irradiation. Electromagnetic radiative heat exchange involving graphene nanostrucrures is studied using an atomistic approach based on the coupled dipole method modified by the fluctuation dissipation theorem. The results are mentioned shown, but will be discussed in detail elsewhere. Salivary cooling, escape reaction and heat pain in capsaicin-desensitized rats. Residents reported emotional distress correlated with the loss of a house or intrafamilial illness or mortality.

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A 40-year-old female with metastatic breast cancer developed multiple lung nodules some of them with cavitations. These materials were capable of specifically inhibiting the binding of IgE to rat basophilic leukaemic cells (RBL) in vitro and to rat tissue mast cells in vivo. Immunohistochemistry (IHC) with an antibody against HCV (Rb 246) was also used to analyze HCV viral protein in the tissues. Cannibalism often was favored by density-dependent factors for herbivores that feed in concealed feeding situations (such as stem borers, leafminers), but also by density-independent factors (such as high ambient temperature) for herbivores that feed in exposed feeding situations. We obtained ChAT-immunoreactive staining of amacrine and displaced amacrine cells in the retina and type XIV cells in the tectum, but we obtained no direct immunocytochemical evidence that ganglion cells in the goldfish retina are cholinergic. After 12 months of ERT, MRI was normal in 3/7, showed the same WM lesions in 2/7, and showed worsening of WM lesions in 2/7 patients (from the same family). The results of this study support further investigation of higher doses of cerivastatin given the excellent safety profile at doses up to 0.3 mg. Cysteine residues function in the catalytic cycle of many enzymes, and they form disulfide bonds which contribute to protein structure. ethambutol name brand This article discusses the role of microglia in CNS immunity and highlights key advances made in glioma immunology.

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Randomized clinical trial of Ligasure versus open haemorrhoidectomy. There is a need for a common vehicle to integrate this data and to allow the testing of hypotheses concerning development. The physiology of pupillary responses is introduced, leading to an outline of early pupillometry work, which began with the seminal work of Hess and Polt in the 1960s. This integration will subsequently be used in real-time event stream processing in intelligent patient monitoring devices. This study is the first to clearly determine the relative concentrations of IL-1 beta and IL-6, using enzyme-linked immunosorbent assay quantification. We show the results of analyzing the phages lambda, T7 and fd, and the E. Here, we capitalized on a sequential saccade task in which macaque monkeys acquired repetitive scanning sequences without instruction. In silico analyses were performed to provide further comprehension of the feasibility for predicting successful capsid formation. The maximum depression of activity occurred after 20 mg/kg was administered to the dam.

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This article will discuss the current state of the juvenile justice system, the literature on the use of telemental healthcare (TMH) with delinquent youth, how TMH fits within the generally accepted model of correctional rehabilitation, and special considerations for applying TMH to this population and setting. Our results suggest that total invertebrate what does flagyl tablets look like abundance has a direct influence on spider richness and abundance, whereas the effects of precipitation were mainly indirectly related to most spider assemblage parameters. MiR-548-3p functions as an anti-oncogenic regulator in breast cancer. For their identification the RFLP fingerprinting method was used based on evidence of repeated sequence of IS6110 in the chromosomal DNA of the examined strains of Mycobacterium tuberculosis predigested with restrictive enzyme PvuII. New principles in the assessment of body functional status during sanatorium treatment. Paradoxically, evidence is mounting that structurally intact Runx genes are also oncogenic when overexpressed. Characterization of protease cleavage sites involved in the formation of the envelope glycoprotein and three non-structural proteins of dengue virus type 2, New Guinea C strain.

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Some authors think the pectoral fascia will be broken during the operation because it is thin and weak. Thus it is probable that the YWR accession evolved from a spontaneous hybrid between wild rice and an ancient cultivated strain of domesticated rice. Moreover, cell cycle analysis showed that inhibitors alter the cycle by arresting cells in different phases. Possible changes in oxygenation-associated rate constants between Rubisco forms are discussed. A threshold value at 7.8 mmol/l with a smaller number of women requiring the 75 g oral glucose challenge test may be more acceptable. We reported previously that nuclear factor-kappaB (NF-kappaB) was constitutively activated in ATL cells, although expression of the viral proteins was barely detectable, including Tax, which was known to persistently activate NF-kappaB. Direct Dating and Physico-Chemical Analyses Cast Doubts on the Coexistence of Humans and Dwarf Hippos in Cyprus. Both LA and LM subjects emptied comparable amounts of milk meals having similar osmolarity.

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The olfactory identification performance of T-RS patients was significantly lower than that of normal controls but not significantly different from either affective disorder group. Although much is known about the precision of visual perception in cluttered scenes, relatively little is understood about acting within these environments - the spatial resolution of visuomotor behavior. Northern analysis was used to measure mRNA levels of cathepsins B, H, K, L, and S, and cystatin C in total RNA extracted from knee joints of Del1 mice, using their non-transgenic litter mates as controls. Axonal loss from acute optic neuropathy documented by scanning laser polarimetry. Although many authors agree with the opinion that some of these drugs, above all aerosols of acetylcysteine at convenient dosages, provided they are associated with beta 2-sympathomimetics, may be useful in the tetracycline dosage mrsa treatment of bronchial obstruction due to inspissated mucus in excess in the lumens, many specialists remain reluctant concerning the activity of mucolytics given by mouth. Hyperfiltration as a mechanism of renal damage in human systemic hypertension has not been established. Although the chimeras indicated genotype-specific evolution of M, rapid selection of a compensatory mutant suggested conserved mechanisms of lyssavirus assembly and the requirement for only few adaptive mutations to fit the heterogenotypic M to a RABV backbone.

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The problem of non-specific binding of beta-endorphin during competitive inhibition assays was circumvented through a two-step process levaquin and alcohol interaction in which the plate was first coated with BSA, followed by a second plate coating with poly-lysine (MW4000). The pineal of the troglophilic fish, Chologaster agassizi: an ultrastructural study. Malignant neoplasms induced in rats by extracts from human sarcomatous tissue. The macrophages increased steadily in number during the first 1-2 wk of culture. The human XIST transcript was expressed and could coat the mouse autosome from which it was transcribed, indicating that the factors required for cis association are conserved in mouse ES cells. Results with ciprofloxacin are less conclusive and warrant further investigation. Fos-like immunoreactivity was used to compare the auditory brain stem excitation elicited by bipolar electrical stimulation of the cochlea at various current levels relative to the electrically evoked auditory brain stem response threshold for a 50-micros/phase monophasic pulse. Thermophilic bacteria were present in some of the soils, and a significant portion of the bacterial population was capable of growth at 2 C. The aim of the present study was to investigate the association of negative priming and schizotypal personality using a Stroop-version of the paradigm.

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Coordination changes demonstrated by subjects with hemiparesis performing hand-arm training using the NJIT-RAVR robotically assisted virtual rehabilitation system. Treatment of infectious outbreaks in neutropenic patients with a piperacillin and amikacin combination. A two-hour training session, including five successful light-guided intubations using the TL, was inadequate for producing acceptable success rates during manikin intubations by paramedic students. The effectiveness of the spa and health resort-based treatment with the application of Essentuki-type drinking mineral waters for the management of non-alcoholic fatty liver disease in the patients presenting with type 2 diabetes mellitus. Purification and characterization of diacylglycerol lipase from human platelets. Studies of correlation between AI and PI, between AI and survival, between PI and survival, and between the ratio AI/PI and survival, were performed using the Spearman rank correlation test. Identity (ID) badges and lanyards worn by pediatric health care workers (HCWs) have been shown to be potential vectors of nosocomial bacterial infections.

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Ultrastructural observations on the expression of axonin-1: implications for the fasciculation of sensory axons during axonal outgrowth into the chick hindlimb. Transmission electron microscopy was used to investigate the supramolecular structure of Araneus diadematus (garden spider) cocoon silk. ECG diagnosis of left ventricular hypertrophy associated with a left anterior fascicular block. Ability of sera from mice treated with Ge-132, an organo-germanium compound, to inhibit experimental murine ascites tumors. If a process of dystrophic calcification is also encountered the differential diagnosis can be a challenge even after histological analysis, as it is highlighted by our case. Also, the mutated AQP-2 is functionally divided into two types of abnormality.

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Taking all these data together, it can be concluded that the organism from ostriches is a new species whose proposed name is Entamoeba struthionis n.sp. There were no documented IOL opacifications following penetrating keratoplasty or sole cataract extraction. Adenovirus transforming 19-kD T antigen has an enhancer-dependent trans-activation function and relieves enhancer repression mediated by viral and cellular genes. A series of pyrimido-pyrimidine derivatives were tested for their effect on membrane fluidity-deformability of human red blood cells and on human platelet aggregation. Overexpression of CYP7A in hamsters results in a reduction of serum cholesterol levels, suggesting that the enzyme plays a central role in cholesterol homeostasis. With regard to flagyl causing yeast infection molecular mechanisms, cortical spreading depression upregulates a variety of genes coding for COX-2, TNF-alpha and IL-1beta, galanin or metalloproteinases. Side effects of treatment were few, and those that could be attributed to antibiotic use occurred with equal frequency in the two treatment groups. Transcutaneous ultrasonography showed a vascular tumor of the parapharyngeal space with complete encirclement of the internal carotid artery.

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The high expression of the reporter gene in SRD-2 cells was not observed when the FPP synthase promoter contained a three base pair mutation within an SREBP binding site, termed sterol regulatory element-3 (SRE-3). Following a request from a Governmental Interdepartmental Group, the Health and Safety Executive undertook a polychlorinated dibenzo-p-dioxin (PCDD) and polychorinated dibenzofuran (PCDF) sampling exercise at several work sites in the UK. In 19 patients with Parkinson disease, we studied the relationship of the therapeutic effect of levodopa, or dyskinesia, to the plasma content of DOPA and growth hormone (GH). In this study, we investigated the: 1) pathogenesis and morphology of bone metastases in the MATLyLu rat prostate adenocarcinoma model, and 2) effect of PTHrP overexpression on tumor growth and incidence of bone metastasis. brucei parasites using both minisatellite allele length and MVR mapping are described in full and can be easily adapted to apply to mini-satellites in other parasites. Dopamine agonist induced self-mutilative biting behavior in monkeys with unilateral ventromedial tegmental lesions of the brainstem: possible pharmacological model for Lesch-Nyhan syndrome. Although screening tests to prevent anaphylaxis during anaesthesia have been advocated, such tests are unlikely to have significant impact on reducing the incidence of anaphylaxis during anaesthesia.

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