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Klonacid (Clarithromycin)

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Klonacid is used for the treatment of various infections in the body like infections of the throat, sinus, skin, soft tissue, chest (infection of lungs and windpipe). It is also used in the treatment of ulcers in the intestine caused by bacteria known as helicobacter pylori. It is also used for pneumonia as well as for skin infections.

Other names for this medication:
Biclar, Bicrolid, Binoclar, Bremon, Cidoclar, Clabact, Clabel, Clacina, Clarimac, Clarimycin, Clarix, Clarogen, Claromac, Clarosip, Claxid, Cleanomisin, Egelif, Emimycin, Eracid, Fromilid, Gervaken, Hecobac, Heliclar, Infex, Kalecin, Kalixocin, Klabax, Klabion, Klarit, Kleromicin, Kofron, Krobicin, Likmoss, Macrol, Mononaxy, Monozeclar, Odycin, Rodizim, Rolicytin, Synclar, Taclar

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Also known as: Clarithromycin


Klonacid (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Klonacid works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


Klonacid is available in tablets. Take Klonacid orally. Take Klonacid with full glass of water. Take Klonacid with or without food. Do not crush, chew, or break the Klonacid tablet. Swallow the pill whole. Shake the Klonacid oral suspension well before measuring a dose. Measure the Klonacid oral suspension with a marked measuring spoon or medicine cup. Take Klonacid for for 7 to 14 days. The dosage and the kind of medication depend on the disease and its prescribed treatment. Do not stop taking Klonacid suddenly.


If you overdose Klonacid and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Klonacid overdosage: nausea, vomiting, diarrhea, abdominal discomfort.


Store Klonacid XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Klonacid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Klonacid if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao). Do not take Klonacid if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Klonacid if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane). Do not take Klonacid if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome". Try to be careful with Klonacid usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Avoid consuming alcohol. It can be dangerous to stop Klonacid taking suddenly.

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Distribution of enterotoxigenic staphylococci in rats (Rattus norvrgicus) and biological properties of the isolates. The presence of first rank symptoms (FRS) has been associated with cognitive abnormalities, e.g., deficits in self-monitoring or in the experience of agency, suggesting that a specific network of neural abnormalities might underlie FRS. Alcoholism: medicosocial aspects and outlines of alcoholism prevention. Normal quiescent lymphocytes regulate their ribosome content by selectively degrading newly synthesized 18S ribosomal RNA. Structured, face-to-face interviews were conducted with 62 of 73 key decision makers. Entanglement Measures for Single- and Multireference Correlation Effects.

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The phrenic nerves showed axonal dystrophy at the site of electrode implantation and more severe distal degeneration. All women receiving marital check-ups are issued PHC booklets and then their menstrual dates are recorded regularly. The ocular finding of the patients with Pro216Leu mutation of RDS gene included severe visual loss and diffuse distribution of pigmentary changes with macular degeneration. Antinuclear antibody in the serum was not detected and specific patterns of immunoglobulin deposition in the epidermis or basement membrane zone were lacking. Climate change: Assessing effects on health and wealth of populations. Using a learning criterion in a probabilistic object reversal task, we found a learning stage by age interaction in the dorsolateral prefrontal cortex (dlPFC) during decision making. We show that the B-domain of SEPT9 binds to three sites on F-actin, and the two of these sites overlap with the binding regions of myosin and cofilin. The nature of benzo(a)pyrene-DNA adducts formed in hamster embryo cells depends on the length of time of exposure to benzo(a)pyrene. Adherent cell depletion of the total leucocyte population did not affect the ability to respond in MLR but did ablate the stimulatory capacity of hagfish leucocytes. Horizontal narrowing of palpebral fissure and inversus epicanthal folds are the main clinical feature to be considered when differential diagnosis is difficult between primary forms and blepharophimosis, as ptosis is often an underlying abnormaly in both cases.

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Perfusion lung scintigraphy revealed multisegmental perfusion defects. Discontinuation of treatment after ovulation caused hyperprolactinemia during the luteal phase. Several weather factors, such as temperature, precipitation, wind force and humidity were analyzed in relation to RSV epidemics without disclosing an important relationship. Role of the ventromedial hypothalamus in prolactin-induced hyperphagia in ring doves. This study shows that small biopsy samples of fibres are not necessarily representative of the whole muscle and that there is a need in subsequent studies to define precisely biopsy location. Participants will be recruited from PR assessments, primary care and community rehabilitation programmes. Isolation and preliminary characterization of a Chinese hamster ovary cell line with high-degree resistance to hydrogen peroxide. Furthermore, the spheres exhibited the superparamagnetic characterization when the thickness of the Fe3O4 shell was less than 15 nm. The heart failure syndrome is one the most common chronic diseases in western countries with poor prognosis. IL-8 is associated with stages of COPD, which may serve as an indication for clinical progress.

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We examined the MMR in sinonasal airway mucosa to evaluate its possible role in chronic rhinosinusitis (CS) and nasal polyposis (NPs). A production study was carried out in which ten speakers produced Dutch lexical and reiterant disyllabic minimal stress pairs spoken with and without an accent in a fixed carrier sentence. Two microdialysis probes were inserted into the right and left cortices of a gerbil subjected to a focal cerebral ischemia. Potential role of lamivudine (3TC) in the clearance of chronic hepatitis B virus infection in a patient coinfected with human immunodeficiency virus type. The goal of comparative effectiveness research (CER) articulated by the United States government is to provide information on relative strengths and weakness of medical interventions.

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What attributes guide the deployment of visual attention and how do they do it?. All patients who underwent kidney transplantation in our center between 2009 and 2013 were reviewed. The relationship of microsomal cholesterol and phospholipid fatty acid composition to the activities of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase and acyl-CoA: cholesterol acyltransferase was investigated in male, female virgin and pregnant rats when hepatic cholesterogenesis was stimulated by cholestyramine. These results are discussed in the light of different metabolic pathways of coumartin in both species. Synchronism and diachronism in the evolution of the concept of disease. The fact that this anomaly could be detected by prenatal ultrasound scanning is of value in the counselling of high-risk pregnancies such as this. Laser light was delivered either by a fiber optic probe maintained at a fixed distance, or via a slit lamp system, for intervals of up to 20 minutes. The synovial membrane is postulated to synthesize beta-endorphin. Decreasing assault occurrence on a psychogeriatric ward: an agitation management model. Tissue typing of the family revealed HL-A 27 antigen in two members and HL-A 17 in the other two members.

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In multivariate analyses, a decline in performance status (PS), an increase in ESR, or a decrease in Hb, were related to a decrease in T, fT, E2, or fE2 levels. ECM may indeed play a key role in the up-regulation of hepatocyte functions in MSC/hepatocytes co-culture. At surgical exploration, cerebrospinal fluid leakage resulted from a fistula in the tympanic segment of the left facial canal. Development of a biomaterial that inhibits bacterial adherence and does not allow upstream colonization of bacteria on the catheter drainage system would significantly influence the rate of catheter-acquired urinary tract infection. Differences in DNA that alter the expression or function of proteins that are targeted by drugs can contribute significantly to variation in the responses of individuals. Diabetes mellitus is a complex group of diseases that has hyperglycemia as a common metabolic abnormality. Six of the patients were surgically treated, and macroscopical examination verified the US findings showing disruption on the dorsal side and a partial rupture in the dorsal and mid-tendon. Intraclass correlations (ICC) were computed for the first day and consecutive additional days (compared with the criterion estimate based on the whole week) to determine the minimal number of days required to achieve a reliability ICC of 0.70, 0.80, and 0.90. Fatigue is a common complaint of patients with cholestatic liver disease. On one hand, the proposed RVMs establish a unified framework of classical classifiers because NN, SVM, and SRC can be interpreted as the special cases of RVMs with different definitions of representative vectors.

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Interaction of the steroid substrates, 17 alpha-hydroxyprogesterone and progesterone, with P-450C21 in the liposomes was studied in the equilibrium state by measuring substrate-induced spectral change. Note on the semi-quantitative determination of urinary catecholamines by the Hingerty method. Measurement of poly(ADP-ribose) glycohydrolase activity by high resolution polyacrylamide gel electrophoresis: specific inhibition by histones and nuclear matrix proteins. It is a distinct pathological entity that presents at birth or during infancy as self-limiting expansile intraosseous lesions involving the body of one or more ribs. A dosage of 20 micrograms/2 h for 200 days resulted in a LH to FSH ratio greater than 2. Packed cell volumes (PCV) of lambs given 20,000 sporocysts decreased dramatically from 28 to 38 dpi after which they slowly returned to near pre-inoculation levels by 99 dpi.

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The seven trans membrane helices were positioned using the helices found in the structure of Bacterio Rhodopsine. Bile flow decrease and altered bile composition in streptozotocin-treated rats. The distribution of the noradrenaline (NA)- and dopamine (DA)-containing neuronal structures in the central nervous system of the hedgehog (Erinaceus europaeus), a phylogenetically old mammalian species, was immunocytochemically studied employing antibodies directed against the catecholamines (CA) themselves. There is a need to identify the impotent patient at an early stage in order to offer more effective treatment. Central administration of the amyloid beta-peptide (25-35) and individual features of cognitive behavior of rats. Although infection generated stronger responses than vaccination, the proportion of responders was similar among individuals with low background titers.

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Hepatic IGF1 DNA methylation is influenced by gender but not by intrauterine growth restriction in the young lamb. Macroscopic sectioning showed a smoothly rounded 29 x 21 x 12 cm tumour attached to a normal left adrenal gland, weighing 4050 gr. Thus, in both their sensory and motor aspects, the weapons of bat/moth warfare have frequently evolved into components of courtship systems. Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing. On the observation of a Baker cyst in a patient with neurofibromatosis the possibility of malignant degeneration must be kept in mind and an operation carried out immediately.

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Mutation at Trp(2) appears to indicate that these oligomeric complexes trans-dimerize. Responsibilities and rights in the promotion of health: differing positions of the individual and the state. This study investigates the relationship between the serotonin transporter linked polymorphic region (5-HTTLPR) and the long-term outcome of antidepressant treatment. Further analyses are needed among potential users to optimize the introduction strategy. Throughout its 25 years of existence, the Protocol Review Committee has streamlined drug and protocol evaluations and has developed standard operating procedures to handle those reviews in a very efficient and fast manner. The animals were followed-up weekly by palpation of the rulide medicine peripheral lymph nodes in order to identify local recurrence.

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Immunological responses to ultraviolet light B radiation in Black individuals. Also, with the various advances in treatment of HIV, neurovascular complications could be seen more frequently as the long-term survival in these patients improves. This animal might prove to be an interesting model in which to study the biology and fibrogenic potential of lipocytes. Preliminary results of a Phase I/II study with pi-meson (pion) treatment for bladder cancer. Unilateral vagus nerve stimulation increased vagus nerve activity, slowed heart rate, recovered autonomic nerve homogeneity and function imbalance, and improved heart function in HF. To investigate the molecular basis of autosomal dominant limb-girdle muscular dystrophy (AD-LGMD) in three large new families.

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Effects of electrotherapy in treatment of neurogenic bladder in children with occult spinal dysraphism. Erratum to: Long-acting methylphenidate formulations in the treatment of attention-deficit/hyperactivity disorder: a systematic review of head-to-head studies. It is thought that the disruption in pollen development is a consequence of mitochondrial dysfunction. Transvaginal color Doppler has made possible to study ovarian and uterine perfusion in non-pregnant and pregnant patients, thus advancing the understanding of the early human development. The proliferation and apoptosis of the two cell lines were observed with MTT assay and flow cytometry. The vasopressor effect of the alpha-1 adrenoceptor agonist phenylephrine was significantly attenuated in DI rats compared with LE rats, whereas the pressor action of angiotensin II was similar in both groups. During the period of treatment and observation lasting 2 weeks, all the assessment criteria showed a more rapid regression in the symptoms and signs of the disorder on treatment with the active product. The case of a 44-year-old male with a traumatic pericuboid fracture-dislocation consisting of disruption of the midtarsal, tarsometatarsal and pericuboid articulations is presented.

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Enzymatic characterization and gene identification of aconitate isomerase, an enzyme involved in assimilation of trans-aconitic acid, from Pseudomonas sp. However, the clinical significance of a poor TMSC on the day of IUI in a patient with prior normal semen analysis (SA) is unclear. The epithelial cells of epididymes of treated lizards exhibited an accumulation of sudanophilic lipid material in their cytoplasm. Over the last few decades, advances in cultivation-independent methods have significantly contributed to our understanding of microbial diversity and community composition in the environment. Significant FAK-Y(397) phosphorylation was observed only after 3 and 5 minutes of pressure stimulus and was blocked entirely by Src inhibition. Cost noroxin 400 mg fiyat -effectiveness of educational interventions to improve patient outcomes in blood pressure control. The clinical outcome of hepatitis virus infections is though to depend on the complex interplay between the host immune response profile and virus factors. The extensive experimental data is processed by a digital computer. The novel method for estimating RGCs yields values that are closer to histological estimates than prior methods, while relying on considerably fewer assumptions. Sagopilone, a microtubule stabilizer for the potential treatment of cancer.

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In this case the postulated chiasmal glioma proved to be an exophytic glioma arising in one intracranial optic nerve and compressing the other. The generation of leukaemia/lymphoma cell microparticles in mature B cell neoplasms appears to be a common phenomenon. Age, coma and S Pneumoniae etiology are the main factors associated with a poor prognosis. Treatment of hypertrophic obstructive cardiomyopathy with verapamil. More subjects in the intramuscular group (17 of 19 subjects) showed a response to anti-HBs than in the intradermal group (14 of 19 subjects). Moreover, the capacity of monocytes from MS patients to act as accessory cells for autologous T cells in the allo-MLR was indistinguishable from that of normal donors. Here it is reported that a cell surface glycoprotein, gp 130, is a major target of increased beta does cipro help sinus infection 1-6-linked branching and that the expression of these oligosaccharide structures is directly related to the metastatic potential of the cells. Co-morbidity of mood and anxiety disorders is often ignored in pharmacotreatment outcome studies and this complicates the interpretation of treatment response.

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Fibrinogen Vicenza and Genova II: two new cases of congenital dysfibrinogenemia with isolated defect of fibrin monomer polymerization and inhibitory activity on normal coagulation. To investigate the relationship between vascular endothelial growth factor (VEGF) microvascular density (MVD), lymph node metastasis and prognosis of breast carcinoma (BC). Practical reasons and reasonable practice: the case of euthanasia in The Netherlands. The result concurs with reports that differences in Cho/Cr ratios observed in patients with bipolar disorder are likely specific to the illness, and are not the result of lithium therapy. A new antitumor and antiviral substance, KS-2, was prepared by ethanol precipitation of the hot water extract of culture mycelia of Lentinus edodes KSLE 007.

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The bait yeast was mated with a prey yeast containing human macrophage cDNA library fused to DNA activation domain. Under this condition, the beam delivery technique used to build a spread-out Bragg peak (SOBP) can influence the relative biological effectiveness (RBE). Mucolytics are generally less effective on mucociliary clearance than beta 2-agonists and theophylline, positive, negative and nonresponders are often seen zithromax 250 mg due to the different viscoelastic properties of the mucus. However, valproate alone or in combination with chronic ketotifen (4 mg/kg) worsened long-term memory. Hormonal control of 17 beta-estradiol biosynthesis in proestrous rat follicles: estradiol production by isolated theca versus granulosa. We conclude that in the absence of confounding variables, nifedipine and phenytoin alter matrix homeostasis in gingival tissue explants ex vivo, and drug administration is a significant factor influencing ECM accumulation in gingival enlargement. The immunoglobulin and complement levels in the active pulmonary sarcoidosis. Archaeological traces indicate that these populations differed in their technology and behavior from earlier hominins. An improved version of this method resulted in the deconvolution of overlapping chromatographic peaks.

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To test this hypothesis, the authors expressed human NR1A/NR2A and NR1A/NR2B NMDA receptors in Xenopus laevis oocytes by injection of messenger RNA prepared in vitro. Toward a decrease in the use of oral cholecystography and intravenous cholangiography. The activities of beta-N-acetylglucosaminidase, beta-galactosidase and beta-glucosidase in the former were distinguished from those in the latter on the basis of solubilization pattern, pH optimum, thermal stability and elution pattern of concanavalin A-Sepharose chromatography. Present data suggest that the anti-excitotoxic effect of mild heat stress is mediated outside of the traditional hsp70 mechanism. The changes in ventricular excitability were studied by a specific protocol in 16 patients. To evaluate the safety of cochlear implantation in children 2 years of age or younger using a non-human primate model. A reconstruction algorithm is derived in the form of a filtered backprojection. Some IL-10 promoter gene polymorphisms predisposed the infected hepatitis B virus cases to cirrhosis in our study population.

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Association between the MHC class I gene HFE polymorphisms and longevity: a study in Sicilian population. Although the social situation for gay, lesbian, and bisexual people has improved over the last decades, lesbian women still face unique challenges when seeking healthcare services. Clear lens extraction led to a significant reduction in IOP, a widening of the anterior chamber angle, and a reduced need for ocular hypotensive medications in eyes with primary angle closure and persistently raised IOP after LPI. Nonconjugative plasmids can be transferred from an Hfr donor to a recipient by Hfr-mediated conduction. The epithelium and superficial layer of the lamina propria were visualized as a high echo (hyperechoic) region, the intermediate layer of the lamina propria was visualized as a low echo (hypoechoic) region and the deep layer of the lamina propria was seen as a hyperechoic region. Physical factors in the treatment and rehabilitation of patients with chronic prostatitis complicated by impotence.

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Cyclosporin has been shown to be highly effective in psoriasis, atopic dermatitis and numerous other dermatoses. As part of a casefinding effort, one hospital-based DM initiative found medical records to be chock full of clues and warning signs of impending major health care problems. Torsional OKN was elicited using a sinusoidal grating rotating at velocities of 3 degrees /s to 1000 degrees /s in clockwise and anticlockwise directions. Elongating the proximal nerve segment may be an alternative to grafting in repairing segmental defects of less than 10 mm. Vitamin D levaquin antibiotic dose metabolism and action in human bone marrow stromal cells. Effect of dose on immune response in patients vaccinated with an her-2/neu intracellular domain protein--based vaccine. Spinal cord arteriography (SCA) often has been considered difficult, hazardous, and unreliable. Obsessional thought disturbance in a gainfully employed PTSD patient. It additionally allowed us to study perceptual differences between increasing and decreasing emotional expressions. These findings provide evidence for a stress-protective effect of sexual activity and mating in male rats and for dissociation between neuronal and neuroendocrine stress responses.

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