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Klarithrin (Clarithromycin)
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Klarithrin

Klarithrin is an antibiotic used to treat various types of infections. It is effective in most infections of the respiratory tract, ear, nose, throat, lungs, and skin. It is also effective against a bacteria known as H. pylori, which is associated with peptic ulcer disease.

Other names for this medication:
Aeroxina, Althromicin, Clacina, Clacine, Clamycin, Clarimax, Claritab, Clariva, Clarocin, Clathrocyn, Clatic, Claxid, Clonocid, Finasept, Gervaken, Glartin, Hecobac, Heliclar, Helozym, Kalecin, Klabax, Klarifor, Klarimax, Klarit, Klarithrin, Klerimed, Larithro, Laromin, Likmoss, Macladin, Macrol, Macromicina, Preclar, Rocin, Rolicytin, Synclar, Veclam

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Levaquin, Biaxin, Ceftin, Cleocin, Rulide, Sumycin, Avelox, Myambutol, Chloromycetin

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Also known as: Clarithromycin

Description

Klarithrin is used to treat many different types of bacterial infections affecting the skin and respiratory system. Klarithrin is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori. Klarithrin fights bacteria in the body. Klarithrin is also known as Clarithromycin, Maclar, Klaricid, Klacid, Clarimac, Claribid.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Klarithrin Filmtab and Klarithrin Granules are recommended as the primary agents. Klarithrin Filmtab and Klarithrin Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Klarithrin is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Klarithrin therapy should continue if clinical response is observed. Klarithrin can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store Klarithrin XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Klarithrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis in Japan. For estimation of APP, a novel statistical method applying tests for a constant postoperative hazard was implemented. gonorrhoeae does not require IgA1 protease production to cause experimental urethritis in males. Molecular imaging of the translocator protein (TSPO) in a pre-clinical model of breast cancer. Given the shared desire to promote the sustained adoption of appropriate technology for assistance and rehabilitation it is suggested the voice of practitioners is strengthened through research and knowledge exchange in the clinical setting. Importantly, many of these findings have implications in our understanding of the pathophysiology of psychiatric disease. Acute gastric mucosal lesions--a new experimental model and effect of parenteral nutrition. The case for parallel classification of biliary tract and pancreatic neoplasms.

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For this reason early tracheostomy, after endotracheal intubation for 24 h at most, is to be preferred in severe pseudocroup. Expression of SR-BI (Scavenger Receptor Class B Type I) in turtle (Chrysemys picta) tissues and other nonmammalian vertebrates. Issues of cost-effectiveness are likely to assume increasing importance in gastroenterology because of the ever expanding range of drug choice, the increasing number of high cost treatments and the development of new therapeutic interventions. A paratertiary-butyl phenol-formaldehyde resin is present in the routine patch test series of the International Contact Dermatitis Research Group. Like prostaglandins, the COX substrate, arachidonic acid, also induced mdr1b gene expression. Compared with the younger foals there was a marked reduction in the number of larvae reaching the small intestine. Five had a diagnosis of soft tissue impingement and underwent debridement with flexor hallucis longus release, 13 had a symptomatic os trigonum that was excised arthroscopically, and 9 had removal of a bony avulsion fragment from the posterior ankle ligament complex.

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Tubulin tail sequences and post-translational modifications regulate closure of mitochondrial voltage-dependent anion channel (VDAC). We further demonstrate that the differences in surface chemistry and topography that develop during aqueous exposure between the single- and double-layer plasma polymer deposits do not affect the adhesion of cells to the surface. Suprofen is a non-narcotic, peripheral analgesic that exhibits potent prostaglandin (PG) synthesis inhibitory activities in a variety of subcellular tissue preparations and in vivo. However, a close correlation between symptoms expression and virus titer existed in some genotypes. This study was undertaken to describe the CT features of primary gastrointestinal stromal tumors in the omentum and mesentery and to identify any pathologic correlation. Pain after barium enema: effect of CO2 and air on double-contrast study.

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The in vivo NK cell response correlated positively with plasma type I/III IFN levels at day 6, as well as with the viral load. The effects of BMI on the result of the GnRH agonist test and levels of obesity-related hormones should be taken into account in girls with precocious puberty. Clinical and laboratory chemical examination in the diagnostic demarkation of chronic lymphatic leukemia. Certain mechanical, infectious, and immunologic problems were responsible for their death. Regulation of p53 gene expression by a poxviral transcription factor. Premature deaths and long-term mortality effects of air pollution. This review article explains the relatively new therapy method of vascular embolization for leiomyomas of the uterus.

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The inherent differences in S-protein trafficking could point to interesting variations in pathogenesis of coronaviruses, since increased levels of surface S protein could promote syncytium formation and direct cell-to-cell spread of the infection. Furthermore, populations evolved under low relatedness caused less mortality to insect hosts, showing how signal evolution in bacterial pathogens can drive the evolution of virulence in the opposite direction to that often predicted by theory. On Social Norms and Behavioral Intentions, the differences were as expected: subjects perceived greater social norms supporting condom use and had stronger intentions to practice safe sex after the intervention than they had before. Protein synthesis and secretion by the rat seminiferous tubule in vivo not affected by experimental varicocele. Prefrontal cortical MHPG levels did not increase in response to vehicle injection or KA infusion into the hippocampus, nor did concentrations of this metabolite increase in the prefrontal cortex in response to intra-VTA KA in animals with neurotoxic lesions of the VTA. normalized peak pressure (NPP) and pressure contact ratio (PCR), which include effects of the weight of the subject, velocity of walking and duration of high pressures in any region of the foot. Interestingly, adult treated rats showed increased spontaneous horizontal activity and a remarkable increase in locomotor response to d-amphetamine as evidenced by increased horizontal and vertical activity. We studied the expression of the HSP-90 isoforms by real-time PCR on pre-treatment biopsy samples. Circadian rhythmicity in back pain: its relationship to short and long interval ibuprofen therapy. Various experimental protocols were used, differing in the choice of experimental material, implant and fixation system and load application.

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We did not find any significant differences in tumor-related gene methylation patterns relevant to both ER and PR status of breast tumors. Although romantic relationships are commonly a source of pleasure and comfort, for some individuals they can be a source of persistent anxiety. Its application exceeds the urological field, it brings also differentially diagnostic possibilities and it is applied also in control of therapeutic results. The prominent role of multidetector CT is primarily defined by its excellent morphologic visualization capabilities, in particular of diffuse or focal intrahepatic lesions as well as of anatomic relationships between the liver and adjacent organs. Through-bond connectivities between the metals and sequentially assigned cysteine residues were obtained with two-dimensional heteronuclear 1H-113Cd correlated spectroscopy. We assessed the utility of maximum oxygen consumption during exercise (MVO2) and diffusing capacity for carbon monoxide (DL(CO)) in the prediction of postoperative pulmonary complications, and the effect of such complications on postoperative length of hospital stay and the cost of hospitalization. Protein-calorie malnutrition and involuntary weight loss continue to be prevalent among hospitalized and long-term care patients, particularly the elderly. Isotype-directed enrichment of B cells by magnetic beads in the generation of immunoreactive human monoclonal antibodies. The initial results of using the zirconium-coated implants offer the challenge for using such devices in future.

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Chlorinated hydrocarbons and their significance for the environment. These incidents include arsenic poisoning in milk, soy sauce, and well water, pollution originating from the Toroku Mine on the island of Kyushu, the Matsuo Mine in Shimane Prefecture and Saganoseki Smelter on Kyushu. We used chromatin immunoprecipitation to study transcription and the direct repeat green fluorescent protein reporter assay to study homologous recombination-mediated DNA repair (HRR). This extends the flexibility to cope with changing environmental demands using a limited number of genes and proteins. Incidence and outcome of cytomegalovirus infections following nonmyeloablative compared with myeloablative allogeneic stem cell transplantation, a matched control study.

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ADCC was assessed with antibody-coated chick erythrocytes as targets. At 37 degrees C, clonidine concentration-dependently decreased the evoked overflow in all brain regions studied, this effect being more pronounced at 0.3 Hz than at 3 Hz. Therapeutic synergy of trimetrexate (CI-898) in combination with doxorubicin, vincristine, cytoxan, 6-thioguanine, cisplatin, or 5-fluorouracil against intraperitoneally implanted P388 leukemia. Posterior circulation CT angiography collaterals predict outcome of endovascular acute ischemic stroke therapy for basilar artery occlusion. In vivo, hypoxia increases the susceptibility of broiler chickens to pulmonary hypertension syndrome (PHS), whereas Leghorns are considered resistant to PHS. Transvenous embolization of traumatic carotid cavernous fistula with mechanical detachable coils. Both these constraints might explain why the timing of reproduction, especially egg formation, is narrow in migratory capital breeders. Pegylation (modification of proteins with polyethylene glycol, PEG) was one of those recently developed approaches to circumvent immunogenicity of legions of drugs. Only ablations including the dorsal anterior region gave rise to a retina lacking a rod free zone. Seven sutureless valve implantations were scheduled using 5 Sorin Perceval and 2 Medtronic 3f Enable valves.

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Crosslinking of cellular DNA by nitracrine and furocoumarin derivatives. Drug therapy began 9 days prior to irradiation and continued for the duration of the study. Optical buffering technique under a space radiation environment. The second mode of presentation (twenty-one patients) was a slower onset, characterized by prior symptoms for varying time-intervals before the more gradual onset of the cauda equina syndrome. We studied load-stress distribution in the pelvis using a three-dimensional finite element model. Nosocomial outbreak of extended-spectrum beta-lactamase SHV-5-producing isolates of Pseudomonas aeruginosa in Athens, Greece. Development of the metanephric kidney during embryogenesis can be altered both in vivo and in vitro by exposure to gentamicin, which may lead to oligonephronia.

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A preliminary analysis of the AEI signal we recorded suggests that cavitation effects can be measured with this technique. The second patient is a 50-year-old man who had a stricture of the left hepatic duct following a right hepatic lobectomy for hepatolithiasis. Formaldehyde-fixed specimens were evaluated for the presence of mechanoreceptors and free nerve endings by neurofilament protein and S-100 protein immunohistochemistry and microscopy. Recurrent fetal cellular rhabdomyoma:histopathological and ultrastructural observation. Their ages ranged from 46 to 86 years with a mean age of 64.7 years.

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One hundred children with normal maxillary central and lateral incisors were subjected to vitality tests each by electrical and pulse oximetry. An outstanding question is whether typical allometric scaling relationships--the power-law dependence of a biological rate on body mass--can be understood by considering the general features of branching networks serving a particular volume. Fast residual stress mapping using energy-dispersive synchrotron X-ray diffraction on station 16.3 at the SRS. Attributable costs of enterococcal bloodstream infections in a nonsurgical hospital cohort. The correlation was significant for plasma levels of AFP above 5,000 ng/ml. To conclude, exposure to high concentrations of lithium did not result in overt toxic effects to LLC-PK1 renal cells, although LiCl did alter some aspects of cell behaviour, which could potentially influence function over time. Pulmonary hypertension (PH) sometimes occurs in patients with systemic lupus erythematosus (SLE). Affirmative Action should not be looked on as lowering standards, but using all available information in the selection process for medical school and residency training to ensure that the medical profession more closely mirrors the diverse racial and ethnic background of the United States population. Characterization of subsets which regulate pokeweed mitogen-induced lymphocyte proliferation and immunoglobulin synthesis.

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Not all relevant drug combinations for evaluation of the interactive potential of a new drug can be examined. In molecular profiling studies of cancer patients, experimental and clinical data are combined in order to understand the clinical heterogeneity of the disease: clinical information for each subject needs to be linked to tumour samples, macromolecules extracted, and experimental results. Outbreaks have occurred in autumn-born lambs from Dorper ewes grazing heavily fertilised Star grass cv No 2 (Cynodon aethiopicus) pastures. The continuous replication of nuclear DNA provides further evidence of dinoflagellate affinity to the prokaryotes, and indicates that Prorocentrum micans is a very primitive eukaryote cell. These sensitivities were in the range of 4- to 80-fold higher than achieved with standard ELISAs using the same reagents. To determine the relative risk (RR) of intracerebral hemorrhage (ICH) among African Americans compared what dosage of zithromax is used to treat chlamydia with that among whites. A randomized controlled trial of hypnotherapy for smoking cessation. Here, the effect of amino acid 106 on the enzymatic properties of the cell-cycle-regulated human cytosolic thymidine kinase 1 (TK1) is investigated. Arsenate did not adsorb to suspended solids and behaved strictly conservatively, exceeding the WHO guideline value for drinking water (0.13 micromol l(-1)) in the entire river system.

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Characterization of cardiac brain natriuretic peptide release in patients with paroxysmal atrial fibrillation undergoing left atrial ablation. Pending further validation efforts, it appears to be the case that researchers may be able to distinguish among different dispositions to rash action prior to adolescence. The progamic phase of an early-divergent angiosperm, Annona cherimola (Annonaceae). An increase in the activity of serum gamma-glutamyl transpeptidase was found in gerbils receiving both light-exposed and nonlight-exposed tryptophan compared to control. It is suggested that sip mutations exaggerate the normal role of c1 in limiting lytic growth. It was also established that the cleavage efficiency strongly depended on the type of spacer connecting the PNA and the peptide. They reported their craving, mood, behaviors, environment, and cigarette-smoking status in 2 to 5 random-prompt entries/day and initiated PDA entries when they used cocaine or heroin or had a discrete episode of craving for cocaine or heroin. Inhibition of pneumococcal carriage in mice by subcutaneous immunization with peptides from the common surface protein pneumococcal surface adhesin a. Our previous study showed roxithromycin syrup dosage that maximum induction of interferon gamma (IFNgamma) and tumor necrosis factor alpha (TNFalpha) was observed at 4 and 8 h, respectively, after an acute po FB(1) treatment.

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The study included a total of 107 patients randomized to uninstrumented posterolateral lumbar spinal fusion with or without DC-stimulation. Tienilic acid in the treatment of arterial hypertension and congestive cardiac insufficiency. We have used electron tomography to obtain low-resolution (2-2.5 nm) three-dimensional maps of both the whole 500 kDa complex and the N-terminally truncated valosine-containing protein-like ATPase from T. We found that high cognitive load and high surprise level were associated with prolonged reaction time compared to low cognitive load and low surprise level, with a synergistic interaction effect, which was accompanied by a greater deactivation of bilateral temporoparietal junction (TPJ). Medical certification and statistical assignment of cause of death. To compare supine nighttime intraocular pressure measurements with Perkins applanation tonometry to 24-h sitting intraocular pressures with Goldmann applanation tonometry. Histopathological findings associated with WNV infections (meningo-encephalitis, myocarditis, and arteritis) were present in all groups, but immunohistochemical detection of the viral antigen was reduced. The aim of our study was to determine whether CDT results change over time between collection of the blood sample and centrifugation, and whether shipment of whole blood samples is a potential source of false positive CDT reports.

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Peak use is amongst the young aged 18 to 25 years, although these figures are now shifting towards earlier teens. Clinicians have long awaited an alternative to invasive endomyocardial biopsy for surveillance of cardiac transplant rejection. Similar quantities of prolactin and GH were released by goats milked when conscious or under anaesthesia. Estimated exogenous insulin concentration was higher (p less than 0.05-0.001) following human ultralente compared to bovine ultralente between 2 and 22 h after injection. The complexity of the relation between NP plasmatic levels and CV and can i take flagyl and drink alcohol renal functions has obvious consequences, as it may limit the predictive value of NP in CV assessment of CKD patients and be a demanding exercise for clinicians involved in the daily management of these patients. In some instances, there was accumulation of relatively long intermediates. We conclude that actin filament bundles are required for microtubule reorientation and growth cone turning to avoid chondroitin sulfate proteoglycan. As in mice, the increased locomotor activity induced by p-OHA microinjection into the NAc in rats was inhibited by nomifensine. A model of the spatial structure of the LBP receptor domain distally limited by four linear loops (two of which are represented by experimentally mapped regions of amino acid residues 187-210 and 263-278) as well as the central beta-folded region turning into the alpha-helical site including residues 200-216 of the LBP molecule and providing for the interaction with the laminin-1 molecule has been proposed. Fast determination of the (1)H relaxivities of MRI contrast agents.

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From July 1, 1979 to June 30, 1983, 136 consecutive patients with category M0 renal cell cancer who had undergone transperitoneal radical nephrectomy at 5 centers entered a prospective randomized trial to compare 500 mg. Secondary immune response to tetanus toxoid (TT), monocyte function, and generation of suppressor cells were studied in myambutol cost patients with previous yersinia arthritis (YA) and healthy controls. Using surface plasmon resonance and electrospray mass spectrometry we were able to show a direct interaction between the two proteins. Bridging CAM practice and research: teaching CAM practitioners about research methodology. These supplementary data serve to reduce the occurrence of legal and conservation controversies and improve reproducibility over time in population genetics studies where genetic monitoring is likely to play an increasing role. The combination of high ligation of the superficial system and compression sclerotherapy for the perforators gives excellent control. Our primary objective was to develop and integrate Computer Assisted Learning (CAL) applications into the undergraduate medical curriculum. These ECM scaffolds are typically prepared from porcine organs such as small intestine or urinary bladder, which are subjected to decellularization and terminal sterilization without significant loss of the biologic effects of the ECM.

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This taxonomic problem has practical implications regarding correct diagnosis of G. This effect adds to the immunoregulatory and antiangiogenic activities operated by IFN-gamma in syngeneic tumour-bearing hosts. Laboratory impact tests should reproduce the phenomena in real impacts, but usually they do not allow the headform to rotate, or ignore the effect of the neck on the motion of the head. In the 58 protocol cases studied there appeared to be an increase in the survival of patients with stage A disease and a significant increase in the survival of patients with stage B disease. A population-based cohort study comparing laparoscopic cholecystectomy and open cholecystectomy. We recently identified the small heat-shock protein alpha B-crystallin as the single immunodominant myelin antigen in MS-affected myelin. The present study found an unexpectedly high national publication output of smaller countries as well as a clearly disproportionate number of published norfloxacin 400 mg tablet price articles from national authors in The Lancet and the NEJM during the years 1986 to 1990 and 1991 to 1995. In contrast to this, FSH antiserum given on the morning of proestrus had no effect on the in vivo and in vitro synthesis of estrogen, when examined 6--7 h later. In the cases of ruptured omphalocele, the bowel wall specimens revealed a subacute inflammatory reaction.

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in the univariate regression analysis, the variables associated with work ability were: education, use of medicine, stress, pain in the last six months and pain in the last week. Collagen fibrillogenesis in vitro: a characterization of fibril quality as a function of assembly conditions. Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway. The experimental data showed that the compensation for ankle-foot and gastrocnemius function offered by the active device resulted in a reduced metabolic cost for the amputee participant. Telephone counseling may provide a viable method for extending psychosocial services to cancer survivors nationwide. Genital ulcer disease (GUD) is common in many developing countries.

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Differences in dye appearance time between the two ocular fundi were larger in cases of angiographically proved stenosis or occlusion of the common or the internal carotid artery. Multitasking in tumor progression: signaling functions of cell adhesion molecules. Suicide in Spain has increased in both genders and in different age groups. We examined rat liver plasma membranes for proteinase activity stimulated by insulin and MnATP. Experimental research on the preparation of dentin-pulp tissue of teeth exposed to CO2 laser beams in dogs and macaques (Macaca mulatta and Macaca fascicularis. Blood biochemistry, Fg concentration, fibrin monomer polymerized velocity (FMPV), absorbance maximum (Amax) and FMPV/Amax were measured. Derangements of anaerobic metabolism reflected by increased lactate and lactate/pyruvate ratios, and release of amino acids were seen at the same time as physiological deterioration in the majority of instances. The present findings suggested that the stretching-induced decreases in PT may be related to changes in the mechanical properties of the muscle, such as an altered length-tension relationship, or a central nervous system inhibitory mechanism. Transforming growth factor beta1 (TGF-beta1) is considered to represent a major fibrogenic mediator in the liver. Identical and fraternal twins were surveyed regarding risk factors implicated in rosacea.

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Noise trauma after inflation of air bags in low speed car crashes. Patients with bilateral polymicrogyria duricef 500 mg capsule were identified from multiple medical centers worldwide. tumefaciens terminates quorum sensing-dependent Ti-plasmid conjugation by degradation of acyl homoserine lactone (AHL) quormone via the enzyme AttM (AHL-lactonase). When combined with a novel distance modulation mechanism, a robust near field microscope can be constructed for operation in aqueous solution. This was particularly so in the self-healed burn, which does however tend to converge in time towards control values. Alamethicin synthetase was extracted from the fungus Trichoderma viride at the end of its exponential growth phase. Significant increases in heart rate and contractility suggest hypoxia-induced activation of the sympathetic nervous system. Inter- and intraindividual variability of the response to intravenous glucose tolerance testing in cats. This situation is indicated by a specific appearance on TII sagittal magnetic resonance images. Diurnal modulation of the minute-rhythmical synchronization state.

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