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Hydramox (Amoxicillin)
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Hydramox

Hydramox is acceptable for uncomplicated acute sinus infections; however, many doctors prescribe amoxicillin-clavulanate (Augmentin) as the first-line antibiotic to treat a possible bacterial infection of the sinuses. Hydramox usually is effective against most strains of bacteria.

Other names for this medication:
Acimox, Almodan, Aloxyn, Amoksicilin, Amoxicilina, Amoxicillinum, Amurol, Bristamox, Cipmox, Flemoxon, Galenamox, Gimalxina, Hydramox, Larotid, Moxicillin, Novamoxin, Ospamox, Penimox, Raylina, Reloxyl, Robamox, Servamox, Solciclina, Stacillin, Tolodina, Velamox, Wymox

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Also known as: Amoxicillin

Description

Generic Hydramox is a perfect remedy in struggle against infections caused by certain bacteria. It is also used with other medicines to treat Helicobacter pylori infection and ulcers of the small intestines. Generic Hydramox acts by killing sensitive bacteria. It is a penicillin antibiotic. Generic Hydramox only works against bacteria, it does not treat viral infections. Hydramox is also known as Amoxicillin, Trimox, Actimoxi, Alphamox, AMK, Amoksibos, Amoxiclav Sandoz, Amoxin, Amoksiklav, Amoxibiotic, Amoxicilina, Apo-Amoxi, Bactox, Betalaktam, Cilamox, Curam, Dedoxil, Dispermox, Duomox, Enhancin, Gimalxina, Geramox, Hiconcil, Isimoxin. Generic name of Generic Hydramox is Amoxicillin. Brand name of Generic Hydramox is Hydramox.

Dosage

Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants 6 months and older, Children, and Adolescents: 80 to 90 mg/kg/day PO in divided doses every 12 hours is recommended by the American Academy of Pediatrics (AAP) as first-line therapy. Do not exceed 500 mg/dose if given every 8 hours or 875 mg/dose if given every 12 hours. AAP recommends a 10-day course for any child with severe disease and for all patients less than 2 years of age, regardless of severity. For children 2 to 5 years with mild to moderate disease, a 7-day course is acceptable. For children 6 years and older with mild to moderate disease, a 5- to 7-day course is acceptable. The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Infants 4 to 5 months: 80 to 90 mg/kg/day PO given in divided doses every 12 hours for 10 days was recommended by experts as first-line therapy in previous guidelines ; however, this age group is not addressed in the most current guidelines by the American Academy of Pediatrics (AAP). The FDA-approved dosage is 20 mg/kg/day PO in divided doses every 8 hours or 25 mg/kg/day PO in divided doses every 12 hours for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours or 45 mg/kg/day PO in divided doses every 12 hours for severe infections.

Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours is the general FDA-approved dosing. Young infants are less capable of responding to infection, and the clinical manifestations of infection can be subtle. Because of the increased risk for complications of an undiagnosed systemic infection, every young infant presenting with a fever should be carefully evaluated.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Hydramox are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Hydramox.

Crystalluria, in some cases leading to renal failure, has also been reported after Hydramox overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Hydramox crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Hydramox. Hydramox may be removed from circulation by hemodialysis.

Storage

Store this medicine at room temperature, away from heat, light, and moisture.

Side effects

The most common side effects associated with Hydramox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Hydramox should be discontinued and appropriate therapy instituted.

A high percentage of patients with mononucleosis who receive ampicillin develop an erythematous skin rash. Thus, ampicillin-class antibiotics should not be administered to patients with mononucleosis.

Prescribing Hydramox in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

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