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Gynoplix (Metronidazole)

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Gynoplix is in a class of drugs called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections.

Other names for this medication:
Amodis, Anaeromet, Aristogyl, Avidal, Corsagyl, Dirozyl, Dumozol, Efloran, Emedal, Etron, Filmet, Flagemed, Flagolin, Flazole, Florazole, Giardyl, Gynomix, Gynoplix, Imizine, Kilpro, Klion, Medazol, Metazol, Metrobac, Metrol, Metronid, Metronidazol, Metronidazole, Metronour, Metrozin, Metrozine, Metrozol, Micogyl, Molazol, Nidazea, Orogyl, Padet, Pharmaflex, Protogyl, Riazole, Rodogyl, Stomorgyl, Trichopol, Trogyl, Vagimid, Vandazole

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Also known as: Metronidazole


Gynoplix (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Gynoplix is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


In the Female. One-day treatment – two grams of Gynoplix, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.


In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Gynoplix overdose, Gynoplix infusion should be discontinued. Patients should be treated symptomatically.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Gynoplix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Hypersensitivity. Gynoplix Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Gynoplix Tablets is contraindicated during the first trimester of pregnancy.

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Choroidal melanomas: correlation of NMR spectroscopy and MR imaging. Quantification of epidermal growth factor receptor T790M mutant transcripts in lung cancer cells by real-time reverse transcriptase-quantitative polymerase chain reaction. As the extreme case of self-organisation, structural genes of different enzymes might have been fused in the course of evolution, giving rise to multifunctional enzymes. A cross-sectional prevalence survey was conducted in urban and rural South African children to measure levels of EIB. Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor. Histology 5 weeks after spinal cord injury revealed that MSC were tightly associated with longitudinally arranged immature astrocytes and formed bundles bridging the epicenter of the injury. Similar reductions in self-stimulation rates could be observed in animals exposed to carbon monoxide or the organic solvent, trichloroethylene.

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