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Evabit (Levofloxacin)
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Evabit

Evabit is similar to ampicillin in its bactericidal action against susceptible organisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell wall mucopeptide. Evabit has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections.

Other names for this medication:
Acquire, Anlev, Cinacol, Corbic, Evonex, Floximax, Floxlevo, Letab, Levocine, Levodak, Levoflox, Levovid, Levoxal, Lovequin, Loxin, Nevotek, Nufalev, Olcin, Orlev, Potant, Recamicina, Tavaloxx, Voflaxin, Volequin, Voxin

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Also known as: Levofloxacin

Description

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Evabit and other antibacterial drugs, Evabit should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Evabit Tablets/Injection and Oral Solution are indicated for the treatment of adults (≥18 years of age) with mild, moderate, and severe infections caused by susceptible strains of the designated microorganisms in the conditions listed in this section. Evabit Injection is indicated when intravenous administration offers a route of administration advantageous to the patient (e.g., patient cannot tolerate an oral dosage form).

Dosage

You should take it by mouth. The treatment can be resulting after 7-14 days or 6 weeks. Take Generic Evabit once a day with water. Do not crush or chew it. Do not stop taking Generic Evabit suddenly.

Overdose

If you overdose Generic Evabit and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Evabit overdosage: poor coordination, tremors, seizures, collapse, breathlessness, lack of movement.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep in a tightly closed container. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Evabit are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Risk of tendinitis and tendon rupture is increased. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroids, and in patients with kidney, heart and lung transplants. Discontinue if pain or inflammation in a tendon occurs.

Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, may occur after first dose.

Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities may occur after multiple doses.

Hepatotoxicity: Severe, and sometimes fatal, hepatoxicity has been reported. Discontinue immediately if signs and symptoms of hepatitis occur.

Central nervous system effects, including convulsions, anxiety, confusion, depression, and insomnia may occur after the first dose. Use with caution in patients with known or suspected disorders that may predispose them to seizures or lower the seizure threshold.

Clostridium difficile-associated colitis: evaluate if diarrhea occurs.

Peripheral neuropathy: discontinue if symptoms occur in order to prevent irreversibility.

Prolongation of the QT interval and isolated cases of torsade de pointes have been reported. Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval.

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Therapeutic implications of intratumor heterogeneity for TP53 mutational status in Burkitt lymphoma. To determine the cell density and expression of proliferating cell nuclear antigen (PCNA) in the lens epithelium of children and aging patients with cataract. After a year of follow-up, evolution was stable and renal function significantly improved. We tested an alternative explanation: that dominant diatom species impair the reproductive success of their grazers. Ethylene glycol is a serious toxin that children frequently ingest. Our purpose was to investigate whether DNA flow cytometric quantification and DNA polymorphism analysis are useful for cytogenetic diagnosis in the case of a complete hydatidiform mole that coexists with a living fetus. In addition, a subgroup analysis excluding infants with perinatal complications was conducted.

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