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Claromycin (Clarithromycin)
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Claromycin

Claromycin belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection.

Other names for this medication:
Aeroxina, Bacterfin, Biotclarcin, Clacee, Clamycin, Clarimycin, Claripen, Claritrox, Claritt, Clarogen, Claromycin, Clarosip, Clarytas, Clatic, Claxid, Cleanomisin, Clormicin, Eliben, Euromicina, Ezumycin, Fromilid, Gervaken, Hecobac, Helimox, Italclar, Kalixocin, Karid, Klabion, Klarifor, Klariger, Klarimax, Klarith, Laricid, Larithro, Lekoklar, Likmoss, Lyoclar, Macrobid, Monozeclar, Odycin, Preclar, Rocin, Synclar, Uniklar

Similar Products:
Terramycin, Flagyl, Keflex, Amoxil, Vantin, Suprax, Cleocin, Ceftin, Cipro

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Also known as: Clarithromycin

Description

Claromycin (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Claromycin works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Claromycin Filmtab and Claromycin Granules are recommended as the primary agents. Claromycin Filmtab and Claromycin Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Claromycin is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Claromycin therapy should continue if clinical response is observed. Claromycin can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store Claromycin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Claromycin out of the reach of children and away from pets.

Side effects

The most common side effects associated with Claromycin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Implication in stone formation during the course of chronic calcifying pancreatitis. The same pattern is seen in placentas associated with preeclampsia. Women appear to be underrepresented among patients who receive implantable cardioverter defibrillators and cardiac resynchronization therapy devices. To analyze and compare the immediate change in chest volume of patients treated with the derotation method of Cotrel-Dubousset versus the sublaminar wire translational technique of ISOLA. Lack of elevation of beta-thromboglobulin and platelet factor 4 in plasma during exercise in patients with chronic peripheral arterial occlusive disease. Attaining proper occlusal adjustments to reduce the lateral occlusal force is recommended in implant-bone-prosthesis system. To explore the relationship between enteral nutrition and the change in intestinal mucosal blood flow during intestinal ischemia/reperfusion injury. A comparison of 2 survey methods: the telephone versus the mails in the diabetic population of a health center.

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Patient demographics, observed (O) and expected (E) morbidity and mortality, and indices (O/E) were evaluated. Knowledge of imaging features of adrenal lesions on radiologic and nuclear medicine imaging will facilitate differential diagnosis and assessment of malignant potential. The relevant phase diagram has been constructed and the stability and mobility of phases is discussed. Quality of life in stoma patients: appropriate and inappropriate stoma sites. It has been found that modulation of autoimmunity to HSP is one way to prevent autoimmune disease. We have studied the stability and structure of emulsions formed in the presence of colloidal mixtures of partially hydrophobic titania particles and hydrophilic silica particles. Clinical observation on 100 patients with hyperlipoidemia treated with the traditional drug jiangzhilin.

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All the heavy chain variable region (VH) sequences from Ab1 are nearly identical to the VH sequences of Ab1 anti-GAT monoclonal antibodies. Often, the excluded volume of the ions has first-order effects on measured properties. Total continence is reestablished for half the patients treated with the tape and a third of those with the balloons. Consistent with this idea, long-lasting potentiation by the mGluR agonist tACPD was blocked by inhibitors of heme oxygenase but not NO synthase. This artcile is a critical appraisal of the value of consumer surveys as a service improvement tool in health services--a lesson which needs to be learnt. The purpose of this study was to evaluate the impact of a peer support program on the health outcomes of patients already receiving well-organized, comprehensive diabetes care. In patients treated with enalaprilat before CPB, both new, more sensitive markers of ischaemic myocardial tissue damage increased significantly less than in an untreated control group.

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