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Claromycin (Clarithromycin)

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Claromycin belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection.

Other names for this medication:
Aeroxina, Bacterfin, Biotclarcin, Clacee, Clamycin, Clarimycin, Claripen, Claritrox, Claritt, Clarogen, Claromycin, Clarosip, Clarytas, Clatic, Claxid, Cleanomisin, Clormicin, Eliben, Euromicina, Ezumycin, Fromilid, Gervaken, Hecobac, Helimox, Italclar, Kalixocin, Karid, Klabion, Klarifor, Klariger, Klarimax, Klarith, Laricid, Larithro, Lekoklar, Likmoss, Lyoclar, Macrobid, Monozeclar, Odycin, Preclar, Rocin, Synclar, Uniklar

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Terramycin, Flagyl, Keflex, Amoxil, Vantin, Suprax, Cleocin, Ceftin, Cipro

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Also known as: Clarithromycin


Claromycin (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Claromycin works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.


The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Claromycin Filmtab and Claromycin Granules are recommended as the primary agents. Claromycin Filmtab and Claromycin Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Claromycin is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Claromycin therapy should continue if clinical response is observed. Claromycin can be discontinued when the patient is considered at low risk of disseminated infection.


Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.


Store Claromycin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Claromycin out of the reach of children and away from pets.

Side effects

The most common side effects associated with Claromycin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


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Differential diagnosis of hemorrhagic syndromes caused by pathologic hemostasis in obstetrico-gynecologic practice (clinical lecture). Reductively methylated trypsin is easily prepared and may be useful in place of trypsin where autolysis is otherwise difficult to control. Two of these frequent subtypes were also suspected to be related to small clusters of listeriosis cases during the postepidemic period. The enzyme activity was inhibited by hydroxylamine, iodoacetic acid, or KCN. Socioeconomic and personal background data, including genocide exposure, were provided via interview of a family member or through village administrators. 31P nuclear magnetic resonance spectroscopy: noninvasive biochemical analysis of the ischemic extremity. Increased oxidative DNA damage is observed in sperm devoid of contact with accessory sex gland (ASG) secretion. Cells from a tumor, generated by injection of Ad12-transformed mouse cells into a syngeneic mouse, also expressed low levels of H-2 antigens, indicating that this phenotype is maintained in vivo. Identification of functional domains by use of targeted deletions.

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Implication in stone formation during the course of chronic calcifying pancreatitis. The same pattern is seen in placentas associated with preeclampsia. Women appear to be underrepresented among patients who receive implantable cardioverter defibrillators and cardiac resynchronization therapy devices. To analyze and compare the immediate change in chest volume of patients treated with the derotation method of Cotrel-Dubousset versus the sublaminar wire translational technique of ISOLA. Lack of elevation of beta-thromboglobulin and platelet factor 4 in plasma during exercise in patients with chronic peripheral arterial occlusive disease. Attaining proper occlusal adjustments to reduce the lateral occlusal force is recommended in implant-bone-prosthesis system. To explore the relationship between enteral nutrition and the change in intestinal mucosal blood flow during intestinal ischemia/reperfusion injury. A comparison of 2 survey methods: the telephone versus the mails in the diabetic population of a health center.

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Evaluating mortality and disease severity in congenital diaphragmatic hernia using the McGoon and pulmonary artery indices. nuvA, an Aspergillus nidulans gene involved in DNA repair and recombination, is a homologue of Saccharomyces cerevisiae RAD18 and Neurospora crassa uvs-2. When therapeutic serum levels of cyclosporine were achieved (150-350 ng/ml) the inhibitor rapidly decreased and disappeared with a concomitant normalization of the factor VIII levels. The clinical course and laboratory data were consistent with tubular necrosis. Haemodynamics and pulmonary gas exchange variables were measured at baseline and at stepwise increased inspiratory NO concentrations of 0.1, 0.3, 1, 3, 10, 30 and 100 ppm, each dose being maintained for 15 min. Treatment with acetylcysteine was begun eight hours after the ingestion. However, incidence data using detailed individual assessments from a population-based cohort have not been undertaken. Fabrication and microstructure control of nanoscale mechanical testing specimens via electron beam lithography and electroplating. Fine mapping of the loss of heterozygosity for chromosome 1pter-p36.11 in nasopharyngeal carcinoma.

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The CPMG multiecho spectroscopic image data sets are used to estimate brain metabolite T2 decay parameters in a group of healthy volunteers and in one tumor patient. A custom-made CE instrument with laser-induced fluorescence (LIF) detection, used for the analyses, is described. Dominant negative alpha-subunit of FTase inhibits effects of insulin and IGF-I in MCF-7 cells. Not only do all four identified genes interact one way or another with the cytoskeleton, but abnormality of the latter leads to alterations of the Golgi apparatus with effects on protein processing, and on axoplasmic flow such that one can expect loss of synapses and subsequent loss of neurons with consequent disconnection and loss of neurotransmitters. New incompatible and compatible host-virus relations have been determined. The response to infection by 3 calves (NIA recovered) closely resembled infections seen in splenectomized calves, being markedly more severe than similar infections in intact calves. These data suggest that electrically-stimulated airway preparations are suitable for evaluating the relaxant activity of beta-adrenoceptor agonists, but the relaxant potency should be assessed in preparations lacking inherent tone, such as cat trachea, guinea-pig trachea in the presence of cyclo-oxygenase inhibition, or human bronchus in the presence of 5-lipoxygenase inhibition. To describe the AIDS epidemic in New Zealand, and to discuss the reasons for an apparent decline in incidence. These results may be interpreted as favouring the existence of a non-cycling G2 population in human epidermis. Bracon celer, another braconid but in the Braconinae subfamily, is also reared from the fruit fly in its native range.

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Dislocation is one of the major complications after a total hip replacement and several treatment alternatives have been described for it. Tropisetron was found to act as a noncompetitive antagonist in all locations of the equine intestine. Expression and localization of insulin-regulatable glucose transporter (GLUT4) in rat brain. After treatment, known quantities of 22NaCl and Na2(35)SO4 were injected intravenously into each animal and permitted to equilibrate with body fluids in order to measure sodium and sulphate spaces in various tissues. Ethyl ester fractions of cod liver oil and dihydroxystearic acid. The O-pentafluorobenzyloxime (OPFB)-heptafluorobutyrylester (HFB) derivatives of hemolymph steroid extracts from both male and female Astacus leptodactylus were subjected to negative ion chemical ionization and capillary gas chromatography-mass spectrometry (NCI/GC-MS). However, more knowledge is needed about current attitudes of nursing students and factors influencing these attitudes. Policy statement--Pediatrician-family-patient relationships: managing the boundaries.

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Patient demographics, observed (O) and expected (E) morbidity and mortality, and indices (O/E) were evaluated. Knowledge of imaging features of adrenal lesions on radiologic and nuclear medicine imaging will facilitate differential diagnosis and assessment of malignant potential. The relevant phase diagram has been constructed and the stability and mobility of phases is discussed. Quality of life in stoma patients: appropriate and inappropriate stoma sites. It has been found that modulation of autoimmunity to HSP is one way to prevent autoimmune disease. We have studied the stability and structure of emulsions formed in the presence of colloidal mixtures of partially hydrophobic titania particles and hydrophilic silica particles. Clinical observation on 100 patients with hyperlipoidemia treated with the traditional drug jiangzhilin.

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All the heavy chain variable region (VH) sequences from Ab1 are nearly identical to the VH sequences of Ab1 anti-GAT monoclonal antibodies. Often, the excluded volume of the ions has first-order effects on measured properties. Total continence is reestablished for half the patients treated with the tape and a third of those with the balloons. Consistent with this idea, long-lasting potentiation by the mGluR agonist tACPD was blocked by inhibitors of heme oxygenase but not NO synthase. This artcile is a critical appraisal of the value of consumer surveys as a service improvement tool in health services--a lesson which needs to be learnt. The purpose of this study was to evaluate the impact of a peer support program on the health outcomes of patients already receiving well-organized, comprehensive diabetes care. In patients treated with enalaprilat before CPB, both new, more sensitive markers of ischaemic myocardial tissue damage increased significantly less than in an untreated control group.

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They led to increases in parent and youth knowledge about tobacco use and more negative attitudes toward tobacco. Chlamydia is an obligate intracellular bacterial pathogen that replicates solely within a membrane-bound vacuole termed an inclusion. Several rewarming techniques are available and the decision to use any of them depends on the degree of hypothermia, the condition of the patient, and the rewarming rate possible with the technique chosen. According to our preliminary results, the MHC II/peptide-based approach may provide rational grounds for further development of antigen-specific immunotherapeutic agents such as human-like MHC lI/peptide chimeras endowed with efficient down-regulatory effects in CD4 T-cell-mediated autoimmune diseases such as Type 1 diabetes, multiple sclerosis, primary biliary cirrhosis, and rheumatoid arthritis levaquin antibiotic yeast infection treatment . Accuracy of the registration parameters was assessed by registration of simulated MR data of the known truth.

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