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Claripen

Claripen is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections,lyme disease,strep throat,skin infections, H. pyloriinfection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma,chlamydiaand mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Other names for this medication:
Abbotic, Bacterfin, Biclar, Binoclar, Biotclarcin, Clacee, Clacina, Clacine, Clariston, Clarogen, Claromac, Claron, Clarosip, Clathrocyn, Cleanomisin, Ezumycin, Fromilid, Glartin, Helimox, Helozym, Karin, Klabet, Klabion, Klarimac, Klarimax, Klarit, Lyoclar, Maclar, Nutabact, Taclar, Zeclar

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Also known as: Clarithromycin

Description

Claripen (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Claripen works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

Claripen Filmtab and Claripen Granules may be given with or without food.

Claripen XL Filmtab should be taken with food. Swallow Claripen XL Filmtab whole; do not chew, break or crush Claripen XL Filmtab.

Triple therapy: Claripen Filmtab/lansoprazole/amoxicillin. The recommended adult dosage is 500 mg Claripen Filmtab, 30 mg lansoprazole, and 1 gram amoxicillin, all given every 12 hours for 10 or 14 days.

Triple therapy: Claripen Filmtab/omeprazole/amoxicillin. The recommended adult dosage is 500 mg Claripen Filmtab, 20 mg omeprazole, and 1 gram amoxicillin; all given every 12 hours for 10 days. In patients with an ulcer present at the time of initiation of therapy, an additional 18 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Dual therapy: Claripen Filmtab/omeprazole. The recommended adult dosage is 500 mg Claripen Filmtab given every 8 hours and 40 mg omeprazole given once every morning for 14 days. An additional 14 days of omeprazole 20 mg once daily is recommended for ulcer healing and symptom relief.

Overdose

If you overdose Claripen and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Claripen overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Store Claripen XL Filmtab at 20 to 25 degrees C (68 to 77 degrees F). Excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Claripen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Claripen if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao). Do not take Claripen if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Claripen if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane). Do not take Claripen if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome". Try to be careful with Claripen usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Avoid consuming alcohol. It can be dangerous to stop Claripen taking suddenly.

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Expression of constitutively active RhoA in all tracheal cells mimics the shot phenotype and affects Shot localization in fusion cells. The results were compared to the condition of animals without anticholinergic drug (oxime alone) and control rats that received physiological solution instead of tabun and treatment. Retinal detachment associated with atopic dermatitis had many similarities to the detachment with blunt trauma in types of retinal breaks. On the other hand, genistein, another tyrosine kinase inhibitor, blocked neurite retraction and cell rounding induced by both activation of the EP3 receptor and microinjection of RhoAV14. Western blot and immunohistochemistry were used to determine protein level and cellular localization, respectively, of cyclic adenosine monophosphate-responsive element modulator (CREM) in the testes. The optimization of culture condition for enhanced hydrogen production by Thermoanaerobacterium thermosaccharolyticum W16 was conducted using statistical experimental design and analysis.

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It was found that the presence of poly(HPMA) in the copolymers has not significantly affected the ability of poly(TMAEM) parts of the copolymers to form complexes with DNA, but has an effect on molecular parameters and aggregation (precipitation) of the complexes. Study of the hydrodynamic factors affecting deposition of cholesterol in arteries. Both chi-like sequences are located within 4 bp of the two 4-bp regions of cross over containing the insertion/deletion breakpoints. The gastric half-emptying time T(1/2) of both liquid and semisolid meals was markedly prolonged in patients with marasmus and marasmic KWO. The interaction of different frequency channels, however, has not fully been understood in terms of anatomical substrates. We then tested 11 blood samples from patients with suspected PWS. Is the spontaneously hypertensive rat a model for human hypertension?. Faith is helpful for acceptance of the diagnosis, and families play a key role in the support of the patients. The strategies to regulate and to modulate the propulsive forces during gait initiation in lower limb amputees.

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The purpose of this study was to quantify the effects of exercise treatment programs on changes in body mass, fat-free mass, and body fat in obese children and adolescents. The results suggest that NF-kappaB represents an ancient, generalized signaling system that has been co-opted for immune system roles independently in vertebrate and insect lineages. Pregnancy and the status of the fetus and newborn infant of women with a positive complement fixation test with Listeria monocytogenes antigen. However, the major regulator of Sln-1 activity, tissue inhibitor of MMPs form 1 (TIMP-1), was not induced at the gene level. The result is the creation of new dilemmas for the worker, the medical staff, and society. The results of our study are discussed within the scope of the current state of the art as regards chemopreventing HCC. Antonovsky (1987) defined the sense of coherence (SOC) as the ability to perceive a stressor as comprehensible, manageable, and meaningful. Mild cognitive impairment (MCI) may be a risk for disability, and co-occurrence of slow gait (SG) and MCI may increase this risk. Haemorrhagic Pneumonia was experimentally reproduced after infecting intranasally narcotized minks. Interestingly, these studies demonstrate that these long-lived mutant mice have physiological characteristics that are similar to the effects of calorie restriction, which has been the most effective experimental manipulation capable of extending lifespan in various species.

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With increasing medical and public awareness of both the clinical manifestations and social implications of HIV infection, it is important that all doctors receive guidance on how to deal with these issues. The cytoplasmic proteome included enzymes of the central carbon metabolism, chaperones, enzymes of protein and DNA repair, and oxidative stress. On the other hand, a subset of telomeres is shown to be constitutively present at nuclear speckles irrespective of cell cycle phase, suggesting that nuclear speckles could be the nuclear sites for telomerase recruitment to telomeres. Advances in high-throughput screening, together with rapid progress in genomic and proteomic sciences, have considerably stimulated the development of a variety of biomarker discovery tools and have contributed to the improvement of clinical diagnosis. Cells expressing PKC-betaII showed a twofold increase in nifedipine-sensitive I(Ca).

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