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Clarimed (Clarithromycin)
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Clarimed

Clarimed is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections,lyme disease,strep throat,skin infections, H. pyloriinfection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma,chlamydiaand mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Other names for this medication:
Binoclar, Ciclinil, Clabel, Clacina, Clacine, Clarimac, Clariston, Claritron, Claritt, Clarix, Claryl, Cleanomisin, Clormicin, Derizic, Egelif, Emimycin, Euromicina, Geromycin, Helimox, Helozym, Kailasa, Karin, Klarigen, Klariger, Klarimac, Klarithran, Klaritpharma, Klazidem, Klerimed, Klonacid, Kofron, Laricid, Macrol, Macromicina, Odycin, Preclar, Rodizim, Synclar, Uniklar, Xylar, Zeclar

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Ceftin, Cleocin, Omnicef, Vantin, Noroxin, Floxin, Chloromycetin, Rulide, Suprax, Biaxin

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Also known as: Clarithromycin

Description

Clarimed (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac / Claribid) is used to treat many different types of bacterial infections affecting the skin and respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis (inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.

It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.

It also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Clarimed works by stopping the growth of or killing sensitive bacteria by interfering with their protein synthesis.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Clarimed Filmtab and Clarimed Granules are recommended as the primary agents. Clarimed Filmtab and Clarimed Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Clarimed is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Clarimed therapy should continue if clinical response is observed. Clarimed can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Store Clarimed at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Clarimed out of the reach of children and away from pets.

Side effects

The most common side effects associated with Clarimed are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Concomitant cisapride, pimozide, ergots, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). History of QT prolongation or ventricular cardiac arrhythmia (including torsades de pointes). Concomitant colchicine (in renal or hepatic impairment). Cholestatic jaundice/hepatic dysfunction with prior clarithromycin use.

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Anatomic Ligament Repair Restores Ankle and Syndesmotic Rotational Stability as Much as Syndesmotic Screw Fixation. Heritable patterns of gene activity and gene silencing arise by the formation and the propagation of specific chromatin states that restrict or permit gene expression. For further resources related to this article, please visit the WIREs website. Two groups of patients with acute respiratory disease (ARD) were examined: 57 (the 1st group) had chronic bronchitis, 265 patients (the 2nd group) had no previous history of chronic bronchitis. Transfer reaction of glucosyl residues to maltose and purified oligosaccharides using highly active Leuconostoc mesenteroides NRRL B-512F dextransucrase.

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An extensive sensitivity analysis was conducted on the results regarding the effectiveness. Rhesus monkey TRIM5alpha (TRIM5alpharh) includes RING, B-box, coiled-coil, and B30.2(PRYSPRY) domains and blocks HIV-1 infection by targeting HIV-1 core through a B30.2(PRYSPRY) domain. Each procedure was followed by disappearance of signs and symptoms of myocardial ischemia. Spores, short hyphae and budding cells of all the fungi were observed in the granulomas stained by periodic-acid Schiff (PAS) and methenamine-silver nitrate (Grocott) techniques. The obtained results confirmed the successful deposition of the proposed immunosensor and demonstrated its high potential for the measurement of analytes of clinical interest. Experiments with cholera toxin B subunit (CTb) indicate that the PRC shares a number of common afferent sources with the dorsolateral periaqueductal gray (PAG).

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This study was conducted to test innovative interventions, using experimental designs, to improve the care and outcomes of patients with cancer in rural settings. The age of patients was the only variable shown to have an independent value in predicting survival after TIPS. Gene expression during zombie ant biting behavior reflects the complexity underlying fungal parasitic behavioral manipulation. Identifying patients infected with hepatitis B virus in sub-Saharan Africa: potential for misclassification. To achieve the purpose, we have employed augmented Dickey-Fuller (ADF) and Phillips-Perron (PP) unit root tests in order to examine the stationary properties of the variables. Byssinosis: environmental and respiratory symptoms among textile workers in Sudan.

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Safety of rifampin and pyrazinamide for the treatment of latent tuberculosis infection. Intravascular bone marrow accumulation in persistent polyclonal lymphocytosis: a misleading feature for B-cell neoplasm. A review such as this could help to inform the real-world implementation of the next wave of new HIV prevention technologies such as ARV-based oral pre-exposure prophylaxis (PrEP). Topics covered include the coordination and function of the large multiprotein signaling complexes that are assembled when Fc epsilon RI and other Ag receptors are engaged, new information on human receptor structures and tissue distribution, and the role of the FcR beta chain in signaling and its potential contribution to atopic phenotypes. Muscarinic acetylcholine receptors in the heart of rats before and after birth. In Method B, only two cases of minimal penetration of pedicle cortex were found. Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3). Although primary prevention of cervical and other cancers is available for preadolescent and adolescent girls, rates of HPV vaccine uptake are low. We were able to demonstrate a significant difference in habituation behavior to neutral and negative associated faces respectively.

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Bronchus occlusion by aid of balloon catheter or double lumen tube are intermediate methods to bridge over till defenitive surgery or embolisation of bronchial or pulmonal arteries as complementary methods in patients with pulmonary hemorrhage. The ratio of peak systolic to peak diastolic frequency shift, an angle-independent index of pulsatility derived from the Doppler curve, proved to be an excellent indicator of aortic arch obstruction in the absence of a patent ductus arteriosus. Glycogen synthase activity was increased in the red gastrocnemius but was decreased in the white gastrocnemius. This clinical trial will be developed for patients with advanced refractory cancers of the anatomic true pelvis, such as those originating in the urinary bladder, prostate, rectum, and uterine cervix. Findings suggest strong measurement characteristics for the GSIS with community-residing older adults, including impressive consistency over time.

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