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Azimex (Azithromycin)
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Azimex

Azimex is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Other names for this medication:
Azimed, Azimex, Azinix, Azinom, Azirox, Azithromycin, Azitro, Azitrom, Azitrotek, Aziwok, Azomax, Azomex, Azyter, Bactexina, Imbys, Nifostin, Oranex, Pretir, Rozith, Tanezox, Zedd, Zemycin, Zertalin, Zicho, Zithrox

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Cleocin, Cipro, Duricef, Keflex, Floxin, Zithromax, Chloromycetin, Levaquin, Sumycin, Ceftin

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Also known as: Azithromycin

Description

Azimex (Azimex tablets and Azimex for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azimex has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azimex is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azimex, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azimex is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azimex for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

You should take Azimex orally with a full glass of water 1 hour before or 2 hours after food. Take Azimex at the same time every day. Azimex treats different types of bacterial infections and can be used both by adults and by children. For children: The dosage is dependent upon the child's weight. In treatment of otitis media, take Azimex for 1-5 days. For adults: To treat pneumonia or throat/tonsil infection, the recommended dose is two 250 mg tablets on the first day and then one 250 mg tablet once a day for 4 more days. For the prevention of MAC (mycobacterium avium complex), the recommended dosage of Azimex is 1,200 mg per week. For the treatment of skin or infections, the recommended dosage is two 250 mg tablets on the first day and one 250 mg tablet for another 4 days.

Overdose

If you overdose Azimex and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Azimex overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.

Storage

Keep the medicine in a cupboard, away from heat and direct sunlight.

You may need to keep liquid medicine in the fridge – check the instructions on the bottle. Make sure that the medicine doesn’t freeze.

Make sure that children cannot see or reach the medicine.

Keep the medicine in the container it came in.

Side effects

The most common side effects associated with Azimex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Many drugs can interact with Azimex. There is a partial list. Tell your doctor if you are using: arsenic trioxide (Trisenox); cyclosporine (Neoral, Sandimmune); pimozide (Orap); tacrolimus (Prograf); theophylline (Theo-Dur, Theolair, Theochron); warfarin (Coumadin, Jantoven); another antibiotic, especially clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam); an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), or desipramine (Norpramin); anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam); cholesterol-lowering medicines such as lovastatin (Mevacor), atorvastatin (Lipitor), or simvastatin (Zocor); ergot medicine such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray); heart or blood pressure medication such as digoxin (Lanoxin, Lanoxicaps), diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others; heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace); HIV medicines such as nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Invirase); medicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran); medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon); migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig); narcotic medication such as methadone (Methadose, Diskets, Dolophine); a sedative or tranquilizer, such as alprazolam (Xanax), diazepam (Valium), midazolam (Versed), or triazolam (Halcion); or seizure medicine such as carbamazepine (Carbatrol, Tegretol) or phenytoin (Dilantin).

This list is not complete and there are many other drugs that can interact with azithromycin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

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Piperacillin and tazobactam exhibit linear pharmacokinetics after multiple standard clinical doses. Differential effect of immune cells on non-pathogenic Gram-negative bacteria-induced nuclear factor-kappaB activation and pro-inflammatory gene expression in intestinal epithelial cells. A brief review of diagnostic and treatment issues for young children is followed by a discussion of developmental issues that contextualize the preschool years and have an impact on cognitive and emotional development underlying self-regulation. To determine if the three grades of the Nottingham system correlate with those of the other systems. In support of this, the cellular activities identified here that can efficiently rejoin double-strand breaks, do not show detectable adenylation products. Blood pressure and blood flow through the fistulas were registered during the operation and the flow capacity (flow/BP) was calculated. Rapid detection of venous air embolism by mass spectrometry during bone marrow harvesting. The anergic state can be abrogated by exogenous IL2, suggesting that the mechanism of anergy is a deficiency of IL2 production. Resonance Raman spectra of phycocyanin, allophycocyanin and phycobilisomes from blue-green alga Anacystis nidulans. Assembly of VDAC was dependent on its beta-signal, which is required for assembly in the mitochondrial OM, and on the bacterial Omp85 assembly machinery.

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Two-component signal transduction (TCST) is the most prevalent mechanism employed by microbes to sense and respond to environmental changes. This study demonstrates that the incidence of non-SLN involvement is low in SLN that contains only micrometastatic foci and is within the accepted range of the false-negative rate of SLN. In this case, the scapulothoracic subluxation was not obvious at the time of injury, but progressively worsened over the following 2 weeks. It is recommended that manufacturers change the design of the diathermy console (a minor modification) in order to ensure this operating position. In August 2002, the Department of Health (DH) wrote to all general practitioners (GPs) in England about hepatitis C, enclosing an educational booklet. Non-requiring, non-requiring and phenylalanine inhibited, proline requiring, amino acid group requiring, and arginine requiring auxotypes predominated in all groups of patients. Patients with cystic fibrosis already have to undergo a large number of routine investigations. The rat liver asialoglycoprotein receptor consists of two types of subunits, a predominant polypeptide designated rat hepatic lectin 1 (RHL-1) and a minor polypeptide, RHL-2/3, that comes in two differentially glycosylated forms. Student assistantship programme in practice: First hand experience at Cardiff University.

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Double potentials analysis as a guide to radiofrequency ablation of atrial flutter. Direct estimation of the partition function from computer simulation. Given some hospital use, PACT did not influence the number of days of use. The patient with hemorrhage and prolonged bleeding time: classification and differential diagnosis. This results in the cleavage and activation of the proinflammatory cytokines IL-1beta and IL-18. In this work, we demonstrate that treatment of VSMCs with simvastatin and atorvastatin inhibited Bcl-2 expression in a time and dose-dependent manner, while Bax expression was not modified. Effects of different kinds of processed radix Glycyrrhizae on the activities of the isolated rabbit gut.

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A decrease in expression of p53, bcl-2, and bcl-X(L) was observed after 12 h exposure of 40 microM curcumin. Fatty acid metabolism in hearts containing elevated levels of CoA. Both nanoparticle concentration and size affected hydrogel properties, with similar trends in enhancements observed for elastic modulus and thermal diffusivity. Regional changes in capillary supply in skeletal muscle of high-intensity endurance-trained rats. The authors have found that the maximal rate of synthesis, as indicated by the incorporation of leucine and glucosamine, occurs 16 hr after wounding, 6 hr before wound closure. Such repair synthesis was suppressed by the specific DNA polymerase inhibitor aphidicolin. We designed a simplified heparin binding technique and assessed the safety and efficiency of HBH-HD. A comprehensive review of death and disability should include audit filters of prehospital care, triage, definitive care, and rehabilitation. Baseline visual field characteristics in the ocular hypertension treatment study. Regional haemodynamics and antihypertensive effects during long-term ketanserin treatment.

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After treatment with Neuraminidase, Con A-activated spleen cells had not lost their ability to bind IL 2. These L particles are generated during lytic replication in parallel with full virions, called H particles. A high-dimensional model is used, whereby a finite element approach is employed to estimate translations at the location of each voxel in the template image. ERalpha increases expression and interacts with TERT in cataractous canine lens epithelial cells. Patients with degenerative joint disease associated with radioscapholunate rupture are not candidates for ligament reconstruction. Cell cycle control of activated, synchronized murine B lymphocytes--roles of macrophages and complement C3. The purpose of the present study was to develop a physiologically based pharmacokinetic (PBPK) model in the mouse and to utilize it to evaluate the relative contribution, if any, of gastric alcohol dehydrogenase (ADH) to the bioavailability of ethanol. To identify the most common ADRs, drugs implicated in ADRs, and to assess their causality, severity, preventability and risk factors predisposing to reported ADRs in Jordan. Antisense human telomerase reverse transcriptase inhibits leukemia cell proliferation in vitro.

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The EUELC project engendered a tremendous collaborative effort, and it enabled the EUELC Partners to establish protocols for assessing molecular biomarkers in early lung cancer with the view to using such biomarkers for early diagnosis and as intermediate end-points in future chemopreventive programmes. Results provide a physiological basis to support several performance studies that consistently indicate 3-d x wk(-1) concurrent training does not impair strength development over the short term. Nevertheless, a very small fraction of crossbridges were active at 10mM ATP resulting in very slow myofibrillar shortening. Locomotion coincides with c-Fos expression in related areas of inferior olive and cerebellar nuclei in the rat. We hypothesized that chronic intermittent EtOH (CIE) induces persistent changes in histone modifications across the cerebral cortex (CCx), nucleus accumbens (NAc), and prefrontal cortex (PFC), and that these histone modifications are altered in a knock-in mouse strain with altered sensitivity to EtOH. Satellite DNAs in eukaryotes: does flagyl cure yeast infection a non-adaptive mechanism of speciation which originated with sexual reproduction?. Cardiac magnetic resonance imaging confirmed regional wall-motion abnormalities and was helpful in excluding myocardial infarction diagnosis. Construction of quail-chick chimaeras has provided significant information on the migration and fate of the neural crest and placodal cells. There was no correlation between ANP levels and right atrial pressures or serum sodium concentrations. Design and baseline characteristics of a hypertension intervention program in a South African village: patient awareness and understanding of their disease process are important.

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A fine polyethylene cannula was inserted through an incision in the dura rostral to the injury and run along the dorsal subdural space to the lesion level. The SCID mice, inoculated perorally and examined after 23 weeks, were uninfected. Here we report a repository of 1.9 million variations (SNPs and InDels) anchored on eight pseudomolecules in a custom database, referred as CicArVarDB that can be accessed at http://cicarvardb.icrisat.org/. The relationship between the interferon alpha response and viral burden in primary SIV infection. Generally, steaming and microwave steaming were preferred for certain vegetables, even by those who normally boil them. The diagnostic approach has been greatly facilitated by the establishment of a panel of marker autoantibodies, which do not define distinct therapeutic groups of AIH, but do allow a subgrouping based on differences in patient populations, some clinical features and cleocin 1% gel prognosis.

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Echocardiographic characteristics of hypertrophy and the diastolic function of the left ventricle in hypertension and symptomatic pulmogenic arterial hypertension. Neuronal pattern separation is thought to enable the brain to disambiguate sensory stimuli with overlapping features, thereby extracting valuable information. The output is a simulated number of silverleaf whitefly individuals for each leaf and leaflet on one or more plants. Chemical pathology of diamino acid deficiency: considerations in relation to lysinuric protein intolerance. To assess spinal GABAergic inhibition in the three groups of animals, spontaneous and evoked cell firing rates were recorded before, during and after microiontophoretic application of the GABA(A) receptor antagonist bicuculline.

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Further, physical activity interventions have been less successful in promoting longer-term maintenance. Diagnostic accuracy of DCBE was inferior to colonoscopy, for all size polyps and larg adenomas. The progressive decline in ERbeta expression paralleled the increase in tumor grade. The effect of plasma exchange (PE) for the treatment of acute immune thrombocytopenic purpura (ITP) was assessed both through an analysis of the use of PE for ITP in Canada from 1980 to 1997, and in a study of 23 patients with acute ITP. The technique of subtotal colectomy with immediate ileo-sigmoid anastomosis in the treatment of the carcinoma of the left colon revealed by obstruction is described. To identify cutpoints reflecting Patient Acceptable Symptom State (PASS) and Minimal Clinically Important Improvement (MCII) in patient-reported multi-attribute health flagyl medscape dosage status classification systems and health status measurements among patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA). Changes in migratory behaviour have been observed experimentally and associated with phenotypic switching in various situations, such as the migration-proliferation dichotomy of glioma cells, the epithelial-mesenchymal transition or the mesenchymal-amoeboid transition of fibrosarcoma cells in the extracellular matrix (ECM). Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. A total of 120 prevalent HD patients were included in the study from December 2012 to May 2014. A clinicopathologic study on 9 cases of epithelioid hemangioendothelioma.

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Overall, these results suggest that tyrosine phosphorylated MT1-MMP plays an important role in neuroblastoma progression and that its expression is preferentially observed in tumor specimens from neuroblastoma patients showing poor clinical outcome. Phenytoin acutely augments the neuromuscular block produced by rocuronium without altering its plasma concentration or its binding to plasma proteins. Proinflammatory cytokines and LPS triggered iNOS and HO-1 expression and NO production in PDL cells. The subunits contain approximately 195 base paris (bp) of DNA and histones H2A, H2B, H3, and H4. Laboratory data showed an elevation of alkaline phosphatase and a decreased excretion of Indocyanine green (ICG).

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A randomised, parallel trial comparing a new nutritional programme with a conventional programme. Septic complications have been major problems in the management of patients with obstructive jaundice and neonatal jaundice. The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual HIV-positive men. After inhaling Iloprost, pulmonary shunt how often should i take levaquin 500 mg increased without improvement in oxygen kinetics. Recently, fimbriae have been identified as a possible arising site for the pelvic serous carcinoma (PSC) both in BRCA-positive and BRCA-negative women. The aim of this study was to evaluate the influence of peritoneal fluid on the expression of angiogenic and proteolytic factors in cultures of endometrial cells from women with and without endometriosis. Their pregnancy outcomes were compared with those of control patients followed up with the same testing scheme for a history of stillbirth. Comprehensive coagulation studies were performed on members of a family with combined factor V/VIII deficiency. Upon monochromatic irradiation, quantum yields of OP photolysis have been evaluated and in polychromatic irradiation experiments, apparent first-order kinetic constants have been determined.

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Inhibition of chloride secretion by BaCl2 in the rectal gland of the spiny dogfish, Squalus acanthias. Less intensive outpatient psycho-physical treatments did not improve pain, function or vocational outcomes when compared with non-multidisciplinary outpatient therapy or usual care. This decrease in PG production was not due to lack of precursor, increased metabolism, re-direction of synthesis towards PGE-2, or a direct inhibition by actinomycin D of the conversion of arachidonic acid to PGs. Pulmonary arterial pressure and plasma concentration of atrial natriuretic factor (ANF) in patients with heart disease. Any remaining cells and the cell-free supernatants were used for additional research purposes. A hereditary colorectal cancer registry was reviewed for patients who fit hereditary nonpolyposis colorectal cancer or familial colorectal cancer and hyperplastic polyposis syndrome criteria. It is possible to assess the morphologic changes of levator ani by using 3D MRI models objectively, our 3D data demonstrate larger in LVOL, LPA, LH-W, LH-L, LSG, and the changes in shape. The Co(II)(2) protein reacts with H(2)O(2) to form a complex that is spectroscopically similar to a synthetic model that structurally mimics the oxy-hemocyanin core, whereas the Cu(II)( what does rulide antibiotic treat 2) protein reacted with O(2) or H(2)O(2) does not. The ultrastructural study confirms that the tumor originates from endothelial cells which have lost their capacity to cover the capillary walls.

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