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Azilide (Azithromycin)
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Azilide

Azilide is used for treating mild to moderate infections caused by certain bacteria. It may also be used alone or with other medicines to treat or prevent certain infections in persons with advanced HIV infection. Azilide is a macrolide antibiotic. It slows the growth of, or sometimes kills, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.

Other names for this medication:
Azatril, Azigram, Azilide, Azimed, Azinom, Azithrex, Azithromax, Azithromycin, Azithrox, Azithrus, Azitrocin, Azitropharma, Azitrotek, Azitrox, Azomax, Azomex, Azomycin, Azycyna, Azyter, Azyth, Binozyt, Iramicina, Neblic, Respazit, Rozith, Talcilina, Tridosil, Ultrabac, Zemycin, Zibramax, Zinfect, Zitroken, Zival, Zocin

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Also known as: Azithromycin

Description

Azilide (Azilide tablets and Azilide for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azilide has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azilide is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azilide, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azilide is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azilide for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

You should take Azilide orally with a full glass of water 1 hour before or 2 hours after food. Take Azilide at the same time every day. Azilide treats different types of bacterial infections and can be used both by adults and by children. For children: The dosage is dependent upon the child's weight. In treatment of otitis media, take Azilide for 1-5 days. For adults: To treat pneumonia or throat/tonsil infection, the recommended dose is two 250 mg tablets on the first day and then one 250 mg tablet once a day for 4 more days. For the prevention of MAC (mycobacterium avium complex), the recommended dosage of Azilide is 1,200 mg per week. For the treatment of skin or infections, the recommended dosage is two 250 mg tablets on the first day and one 250 mg tablet for another 4 days.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Azilide overdose may include nausea, vomiting, diarrhea, and stomach discomfort.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Azilide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Generic Azilide if you are allergic to Generic Azilide components.

Do not take Generic Azilide at the same time with antacid contained magnesium or aluminum.

Try to be careful with Generic Azilide while you are pregnant or have nurseling.

Try to be careful with Generic Azilide usage in case of having liver or kidney disease, Long QT syndrome, heart rhythm problems.

Try to be careful with Generic Azilide usage in case of taking cyclosporine (Neoral, Sandimmune), anticoagulants ('blood thinners') such as warfarin (Coumadin), terfenadine (Seldane), digoxin (Lanoxin), dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar), phenytoin (Dilantin), medications that suppress your immune system, nelfinavir (Viracept).

Try to be careful with Generic Azilide usage in case you are allergic to erythromycin (E.E.S., E-Mycin, Erythrocin), dirithromycin (Dynabac), clarithromycin (Biaxin), azithromycin.

Try to be careful with sunbeams. Generic Azilide makes skin sensitive to sunlight. Protect skin from the sun.

Generic Azilide can be taken by children.

It can be dangerous to stop Generic Azilide taking suddenly.

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Application of technique of labeling BMSCs with PKH26 to tissue engineered bone construction. Radiation protection by sulfhydryl compounds and their paramagnetic properties after x-irradiation in relation to their chemical structure. Histopathologic evaluation of cutaneous lesions in scleredema adultorum. Clinico-morphological characteristics of injuries inflicted by shots from weapons of non-lethal action. The transient absorption studies show that the J will flagyl cause a yeast infection -aggregate improves the photoinduced charge separation at the porphyrin/TiO2 interface. The aim of the current study was to assess possible postconditioning with sevoflurane in an in vivo model of endotoxin-induced lung injury.

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