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Azifast (Azithromycin)
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Azifast

Azifast is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Other names for this medication:
Azicin, Azicine, Azidraw, Azihexal, Azilide, Azimit, Azimycin, Azinix, Azithrex, Azithro, Azithrocin, Azitrim, Azitromicina, Azyth, Fabramicina, Faxin, Goxil, Inedol, Macromax, Neofarmiz, Nifostin, Novozithron, Penalox, Phagocin, Pretir, Ricilina, Toraseptol, Triamid, Ultreon, Zaret, Zetamax, Zibac, Zirocin, Zistic, Zithrogen, Zithromac, Zitrofar, Zival

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Also known as: Azithromycin

Description

Azifast is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. In children, it is used to treat middle ear infection, pneumonia, tonsillitis, and strep throat.

Azifast, a semisynthetic antibiotic belonging to the macrolide subgroup of azalides, is used to treat STDs due to chlamydia and gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis, and Mycobacterium avium complex (MAC) in patients with advanced HIV disease. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action.

Bioavailability is 37% following oral administration. Absorption is not affected by food. Azithromycin is extensively distributed in tissues with tissue concentrations reaching up to 50 times greater than plasma concentrations. Drug becomes concentrated within macrophages and polymorphonucleocytes giving it good activity against Chlamydia trachomatis.

Dosage

Dosage of Azifast is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Azifast overdose may include nausea, vomiting, diarrhea, and stomach discomfort.

Storage

Keep the medicine in a cupboard, away from heat and direct sunlight.

You may need to keep liquid medicine in the fridge – check the instructions on the bottle. Make sure that the medicine doesn’t freeze.

Make sure that children cannot see or reach the medicine.

Keep the medicine in the container it came in.

Side effects

The most common side effects associated with Azifast are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome: diarrhea; headache; loose stools; nausea; stomach pain; upset stomach; vomiting.

Seek medical attention right away if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; changes in hearing or hearing loss; chest pain; eye or vision problems; irregular heartbeat; muscle weakness; pounding in the chest; red, swollen, blistered, or peeling skin; ringing in the ears; seizure; severe diarrhea; stomach cramps/pain; trouble speaking or swallowing; yellowing of the skin or eyes.

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