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Amoxicilina (Amoxicillin)
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Amoxicilina

Amoxicilina is used to treat infections caused by bacteria in different parts of the body. The active ingredient is amoxicillin. This belongs to a group of medicines called penicillin. Antibiotics help treat bacterial infections that may be too strong for the body's immune system to clear. The two drugs are very similar.

Other names for this medication:
Alfamox, Almodan, Amoclen, Amopen, Amoram, Amoxi, Amoxicilina, Amoxiline, Amoxypen, Amurol, Bimoxan, Bristamox, Flemoxin, Gimalxina, Hydramox, Larotid, Moxicillin, Novamoxin, Penimox, Raylina, Reloxyl, Robamox, Solciclina, Stacillin, Wymox, Zimox

Similar Products:
Sumycin, Zithromax, Rulide, Cleocin, Amoxil

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Also known as: Amoxicillin

Description

Amoxicilina is one of the best forms of antibiotic available today. It is used to treat infections caused by certain bacteria, including: infections of the ear, nose, and throat (pneumonia, bronchitis); infections of the genitourinary tract; infections of the skin and skin structure; infections of the lower respiratory tract; gonorrhea, acute uncomplicated (ano-genital and urethral infections) in male and females.

Amoxicilina is also used before some surgery or dental work to prevent infection. It is also used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. Amoxicilina may also be used for other purposes not listed here.

Amoxicilina acts by inhibiting the synthesis of bacterial cell wall and stopping the growth of bacteria.

Amoxicilina is available in capsules.

Amoxicilina is usually taken every 8 hours (three times a day). It can be taken with or without food.

The chewable tablets should be crushed or chewed thoroughly before they are swallowed. The tablets and capsules should be swallowed whole and taken with a full glass of water.

Take Amoxicilina exactly as directed. Do not take more or less Amoxicilina or take it more often than prescribed by your doctor. Do not stop taking Amoxicilina without talking to your doctor. To clear up your infection completely, continue taking Amoxicilina for the full course of treatment even if you feel better in a few days. Stopping Amoxicilina too soon may cause bacteria to become resistant to antibiotics.

Dosage

Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants older than 3 months, Children, and Adolescents: 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Neonates and Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Amoxicilina are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Amoxicilina.

Crystalluria, in some cases leading to renal failure, has also been reported after Amoxicilina overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Amoxicilina crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Amoxicilina. Amoxicilina may be removed from circulation by hemodialysis.

Storage

Store this medicine at room temperature, away from heat, light, and moisture.

Side effects

The most common side effects associated with Amoxicilina are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Amoxicilina should be discontinued and appropriate therapy instituted.

A high percentage of patients with mononucleosis who receive ampicillin develop an erythematous skin rash. Thus, ampicillin-class antibiotics should not be administered to patients with mononucleosis.

Prescribing Amoxicilina in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

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