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Acquire (Levofloxacin)

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Acquire is an antibiotic that is used to treat bacterial infections resulting in pneumonia (Fluid build up in the lungs), urinary tract infection, bladder infection, prostate gland infection as well as skin infections.

Other names for this medication:
Acquire, Benfloxin, Cravit, Cravox, Difloxin, Evonex, Floxlevo, Ledric, Lefex, Leflokin, Levocine, Levoday, Levof, Levoflox, Levofloxacin, Levofloxacina, Levofloxacinum, Levomac, Levonix, Levoproxol, Levoquinol, Levores, Levovid, Levox, Levoxa, Levoxal, Levoxetina, Levoxin, Lovicin, Loxof, Nivoloc, Oftaquix, Orlev, Prixar, Septibiotic, Tamiram, Ultraquin, Voflaxin, Volequin, Xenoxin

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Also known as: Levofloxacin


To reduce the development of drug-resistant bacteria and maintain the effectiveness of Acquire and other antibacterial drugs, Acquire should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Acquire Tablets/Injection and Oral Solution are indicated for the treatment of adults (≥18 years of age) with mild, moderate, and severe infections caused by susceptible strains of the designated microorganisms in the conditions listed in this section. Acquire Injection is indicated when intravenous administration offers a route of administration advantageous to the patient (e.g., patient cannot tolerate an oral dosage form).


Rapid or bolus intravenous infusion of Acquire has been associated with hypotension and must be avoided. Acquire Injection should be infused intravenously slowly over a period of not less than 60 or 90 minutes, depending on the dosage. Acquire Injection should be administered only by intravenous infusion. It is not for intramuscular, intrathecal, intraperitoneal, or subcutaneous administration.


Overdose of the drug should be strictly avoided and if anyone has accidentally taken the overdose of the drug, then the victim should be provided with emergency medical help. Overdose victim can also consult to their local poison helpline. Some of the overdose symptoms include loss of coordination, drooping eyelids, weakness, decreased activity, trouble breathing, sweating, tremors, or seizure.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep in a tightly closed container. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acquire are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Risk of tendinitis and tendon rupture is increased. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroids, and in patients with kidney, heart and lung transplants. Discontinue if pain or inflammation in a tendon occurs.

Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, may occur after first dose.

Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities may occur after multiple doses.

Hepatotoxicity: Severe, and sometimes fatal, hepatoxicity has been reported. Discontinue immediately if signs and symptoms of hepatitis occur.

Central nervous system effects, including convulsions, anxiety, confusion, depression, and insomnia may occur after the first dose. Use with caution in patients with known or suspected disorders that may predispose them to seizures or lower the seizure threshold.

Clostridium difficile-associated colitis: evaluate if diarrhea occurs.

Peripheral neuropathy: discontinue if symptoms occur in order to prevent irreversibility.

Prolongation of the QT interval and isolated cases of torsade de pointes have been reported. Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval.

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In 2012, the first Nigerian Hepatitis B Virus (HBV) immune escape mutant (IEM) case was detected in a pregnant woman in southwestern Nigeria. Application of pharmacoeconomics to formulary decision making in managed care organizations. During the first 3 months of life, bone mineral density was reduced, whereas percent body fat was increased in transgenic animals compared with wild-type littermates, with associated decreased bone formation rate and osteoblast number, but normal osteoclast number. An attempt has been made to apply the analytical process to the context of health visiting. Identification, mapping, and genomic structural analysis of an immunoreceptor tyrosine-based inhibition motif-bearing C-type lectin from homozygous clones of rainbow trout (Oncorhynchus mykiss). Here, we show that K1-5 bound to endothelial cell surface ATP synthase and triggered caspase-mediated endothelial cell apoptosis. The path analysis revealed that the genes pobA and pytH had the greatest direct effects on the degradation of beta-cypermethrin (pobA), alpha-cypermethrin (pobA), theta-cypermethrin (pytH) and 3-phenoxybenzoic acid (pytH). We systemically reviewed published studies (January 2007 to September 2013) from full-text databases such as VIP, Chinese National Knowledge Infrastructure, and PubMed and assessed HBsAg-positive rates using a random effects regression model with comprehensive meta-analysis software.

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Surgery for patients with central protruded lumbar discs who have failed conservative therapy. Alpha-tocopherol, ascorbate, catalase, and NAC can inhibit MEP-induced genotoxicity, indicating that ROS might be involved in this effect. Achieving positive changes in behavior related to pain management requires a well-developed plan that incorporates model-based instruction in both cognitive and affective domains. An indirect solid phase radioimmunoassay using rabbit antibodies to the synthetic double-stranded RNA poly rI-rC and 125I-labelled sheep anti-rabbit IgG could detect 1 ng of poly rI-rC. We report the pre-operative preparation and anaesthetic management for resection of an intracerebral tumour during awake craniotomy in a 9-year-old boy.

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PCR amplification and sequence analysis of chromosome fusion junctions revealed exonucleolytic digestion of dysfunctional ends prior to fusion. However, various non-radiotherapeutic modalities such as analgesics, hormone therapy, orchidectomy, cytostatic and cytotoxic drugs, bisphosphonates and surgery are not universally effective. A sample survey covering 201 randomly selected houses in the town was conducted during the epidemic, and records of patients admitted to the only large hospital in this town were reviewed. Gluconeogenic and lipogenic properties of isolated kidney tubules from the domestic fowl (Gallus domesticus). The results indicate that Malaysia is an energy-dependent country and hence energy is stimulus to carbon emissions. Diagnostic significance of IgM anti-HBc detection by ELISA in HBV infection. Effective control of Anopheles minimus s.l., an important malaria vector in Southeast Asia, is based on the accurate identification of species within An.

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Human chorionic gonadotropin levels are significantly lower in multiparous women. The results of this study suggest that hypertonic glucose water is a clinically effective, easily available, and safe sclerosing agent. FOR forms heterodimeric complexes with retinoid X receptor (RXR) as demonstrated by biochemical and mammalian two-hybrid approaches. CT images were used to construct femur and stem model to verify the rotating angle of femur in each X-ray film. The aim of our study was to verify if a single shock could restore sinus rhythm (SR) with a lower discomfort for the pt. Similarly, VEGF mRNA localization, demonstrated by in situ hybridization, was initially highest near the epicardium and then became more evenly distributed transmurally by late gestation. By screening for non-self MHC-bound peptides, the immune system identifies and then can eliminate cells that are producing viral or mutant proteins. We used the data of the above-mentioned workshops to analyze the gain in knowledge and attitudes of the participants, with an idea to develop recommendations for the use of such workshops for increasing the awareness regarding HIV/AIDS. Management of the failing root canal filling begins with the identification of the source of persistent infection. Through a genome, darkly: what is cleocin antibiotic used to treat comparative analysis of plant chromosomal DNA.

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Each SNP was tested for basic obesity-related phenotypes (BMI, waist and hip circumference, waist:hip ratio, fasting glucose, fasting insulin and fasting lipid levels) in 1644 individuals within these 261 families. The inability of the largest ovarian follicle to convert progesterone to androstenedione contributes at least in zithromax 250 mg bonus p part to the preovulatory increase in the plasma concentration of progesterone that generates the preovulatory LH surge by positive feedback. Maternal obesity before and during pregnancy predicts maternal and infant risks of obesity and its associated metabolic conditions. The specific induction of myc protooncogene expression in normal human B cells is not a sufficient event for acquisition of competence to proliferate. Transrectal ultrasound-guided biopsy of the prostate gland: value of 12 versus 6 cores. The nine metals can be divided into two categories in terms of spatial distribution and pollution level.

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Urinary Bladder Paraganglioma: AIRP Best Cases in Radiologic-Pathologic Correlation. These recent developments provide new insights into the functions of this enigmatic receptor. These results are flagyl yeast infection medicine particularly relevant in the light of the recent report that the urokinase-type plasminogen activator receptor, a protein that also binds VN, has been shown to associate with the cation-independent mannose-6-phosphate/IGF-II receptor and suggest a possible role for IGF-II in cell adhesion and invasion. Identification of miRNAs in Bovine Endometrium through RNAseq and Prediction of Regulated Pathways. Twenty-one derived components of the CO2 expirogram were evaluated as predictors of cardiac output. In this report, the structures of the detyrosinated carboxy-terminal peptides of alpha-tubulin from newborn and adult mouse brain were compared. in the absence of dystonia, the expression of Fos-ir did not reveal any differences between dtsz hamsters and controls. Human skin is the first defense barrier against the external environment, especially microbial pathogens and physical stimulation. This is the first report of the CRY-DASH members from vertebrates and fungi. Clinical significance of hemostatic molecular markers in acute leukemia.

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